Job Description P67729 Confidence 100.00% Date Thu Jan 5 12:10:50 GMT 2012 Rank 1 Aligned Residues 411 % Identity 17% Template c2ht2B_ PDB info PDB header:membrane protein Chain: B: PDB Molecule:h(+)/cl(-) exchange transporter clca; PDBTitle: structure of the escherichia coli clc chloride channel2 y445h mutant and fab complex Resolution 3.32 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.			80	.
Predicted Secondary structure																																																																														.	.
Query SS confidence																																																																														.	.
Query Sequence		P	R	A	R	T	M	L	L	L	S	L	P	A	V	A	I	G	I	A	S	S	L	I	L	I	V	V	M	K	I	A	S	V	L	Q	N	L	L	W	Q	R	L	P	G	T	L	G	I	A	Q	D	S	P	L	W	I	I	G	V	L	T	L	T	G	I	A	V	G	L	V	I	R	F	S	Q	G	.	.	H	A
Query Conservation																																																																														.	.
Alig confidence																																																																														.	.
Template Conservation
Template Sequence		E	R	D	K	T	P	L	A	I	L	F	M	A	A	V	V	G	T	L	V	G	L	A	A	V	A	F	D	K	G	V	A	W	L	Q	N	Q	R	M	G	A	L	V	H	T	A	D	N	Y	P	L	L	L	T	V	A	F	L	C	S	A	V	L	A	M	F	G	Y	F	L	V	R	K	Y	A	P	E	A	G	G
Template Known Secondary structure		T	T	T																																										T		S																										T	T		G	G	G	S	S
Template Predicted Secondary structure
Template SS confidence
		27	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.
		82	.	.	.	.	.	.	.	90	.	.	.	.				.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.			.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Predicted Secondary structure															.	.	.																																													.	.
Query SS confidence															.	.	.																																													.	.
Query Sequence		G	P	D	P	A	C	E	P	L	I	G	A	P	.	.	.	V	P	P	S	A	L	P	G	L	I	V	A	L	I	L	G	L	A	G	G	V	S	L	G	P	E	H	P	I	M	T	V	N	I	A	L	A	V	A	I	G	A	R	L	.	.	L	P	R	V	N	R	M	E	W	T	I	L	A	S	A	G	T	I
Query Conservation															.	.	.																																													.	.
Alig confidence															.	.	.																																													.	.
Template Conservation
Template Sequence		S	G	I	P	E	I	E	G	A	L	E	D	Q	R	P	V	R	W	W	R	V	L	P	V	K	F	F	G	G	L	G	T	L	G	G	G	M	V	L	G	R	E	G	P	T	V	Q	I	G	G	N	I	G	R	M	V	L	D	I	F	R	L	K	G	D	E	A	R	H	T	L	L	A	T	G	A	A	A	G	L
Template Known Secondary structure			S									T	T		S																					T	T		S		B	S																			T	T			S
Template Predicted Secondary structure
Template SS confidence
		107	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	A	L	F	G	T	P	V	A	A	A	L	I	F	S	Q	T	L	N	G	S	S	E	V	P	L	W	D	R	L	F	A	P	L	M	A	A	A	A	G	A	L	T	T	G	L	F	F	H	P	H	F	S	L	P	I	A	H	Y	G	Q	M	E	M	T	D	I	L	S	G	A	I	V	A	A	I	A	I	A	A
Query Conservation
Alig confidence																												.
Template Conservation																												.
Template Sequence		A	A	A	F	N	A	P	L	A	G	I	L	F	I	I	E	E	M	R	P	Q	F	R	Y	T	L	.	I	S	I	K	A	V	F	I	G	V	I	M	S	T	I	M	Y	R	I	F	N	H	E	V	A	L	I	D	V	G	K	L	S	D	A	P	L	N	T	L	W	L	Y	L	I	L	G	I	I	F	G	I	F
Template Known Secondary structure						T										T	T	T	T	S		S	S	S				.																						T	T			S											G	G	G
Template Predicted Secondary structure																												.
Template SS confidence
		187	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.		.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.					.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																												.	.	.	.
Query SS confidence																												.	.	.	.
Query Sequence		G	M	V	A	V	W	C	L	P	R	L	H	A	M	M	H	Q	M	K	N	P	V	L	V	L	G	.	.	.	.	I	G	G	F	I	L	G	I	L	G	V	I	G	G	P	V	S	L	F	K	G	L	D	E	M	Q	Q	M	V	A	N	Q	A	F	S	T	S	D	Y	F	L	L	A	V	I	K	L	A	A	L
Query Conservation																												.	.	.	.
Alig confidence																												.	.	.	.																														.
Template Conservation																																																													.
Template Sequence		G	P	I	F	N	K	W	V	L	G	M	Q	D	L	L	H	R	V	H	G	G	N	I	T	K	W	V	L	M	G	G	A	I	G	G	L	C	G	L	L	G	F	V	A	P	A	T	S	G	G	G	F	N	L	I	P	I	A	T	.	A	G	N	F	S	M	G	M	L	V	F	I	F	V	A	R	V	I	T	T
Template Known Secondary structure																			T	T	T	T																								G	G	G	S	S		S	T	T							.	T	T		S
Template Predicted Secondary structure																																																													.
Template SS confidence
		266	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.		.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.							.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
Predicted Secondary structure																																	.	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.	.
Query Sequence		V	V	A	A	A	S	G	F	R	G	G	R	I	F	P	A	V	F	V	G	V	A	L	G	L	M	L	H	E	H	V	.	.	.	.	.	.	P	A	V	P	A	A	I	T	V	S	C	A	I	L	G	I	V	L	V	V	T	R	D	G	W	L	S	L	F	M	A	A	V	V	V	P	N	T	T	L	L	P	L
Query Conservation																																	.	.	.	.	.	.
Alig confidence																																	.	.	.	.	.	.
Template Conservation
Template Sequence		L	L	C	F	S	S	G	A	P	G	G	I	F	A	P	M	L	A	L	G	T	V	L	G	T	A	F	G	M	V	A	V	E	L	F	P	Q	Y	H	L	E	A	G	T	F	A	I	A	G	M	G	A	L	L	A	A	S	I	R	A	P	L	T	G	I	I	L	V	L	E	M	T	D	N	Y	Q	L	I	L	P
Template Known Secondary structure							T	T		S	S	B	S																					T	T		G	G	G	T											T	T	T					T	S																	G	G	G
Template Predicted Secondary structure
Template SS confidence
		345	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.
		387	.	.	390	.	.	.	.	.	.	.	.	.				400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.
Predicted Secondary structure															.	.	.
Query SS confidence															.	.	.
Query Sequence		L	C	I	V	M	L	P	A	W	L	L	L	A	.	.	.	G	K	P	M	M	M	V	N	R	P	K	Q	Q	P	P	H	D
Query Conservation															.	.	.
Alig confidence															.	.	.
Template Conservation
Template Sequence		M	I	I	T	G	L	G	A	T	L	L	A	Q	F	T	G	G	K	P	L	H	S	A	I	L	A	R	T	L	A	K	Q	E
Template Known Secondary structure																T	T															S	S
Template Predicted Secondary structure
Template SS confidence
		425	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.