Job Description P76044 Confidence 95.15% Date Thu Jan 5 12:17:47 GMT 2012 Rank 68 Aligned Residues 192 % Identity 16% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.							40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Predicted Secondary structure																																		.	.	.	.	.	.
Query SS confidence																																		.	.	.	.	.	.
Query Sequence		Q	A	F	F	P	E	N	I	L	E	K	F	R	Y	I	K	E	M	G	F	D	G	F	E	I	D	G	K	L	L	V	N	.	.	.	.	.	.	N	I	E	E	V	K	A	A	I	K	E	T	G	L	P	V	T	T	A	C	G	G	Y	D	G	W	I	G	D	F	I	E	E	R	R	L	N	G	L	K	Q	I
Query Conservation																																		.	.	.	.	.	.
Alig confidence																																		.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		S																	T	T		S										T	T	T		G	G	G	T	T								S				T	T		B							S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		49	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.								.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.
Predicted Secondary structure																																														.	.	.	.	.	.	.																											.	.	.
Query SS confidence																																														.	.	.	.	.	.	.																											.	.	.
Query Sequence		E	R	I	L	E	A	L	A	E	V	G	G	K	G	I	V	V	P	A	A	W	G	M	F	T	F	R	L	P	P	M	T	S	P	R	S	L	D	G	D	R	K	M	V	.	.	.	.	.	.	.	S	D	S	L	R	V	L	E	Q	V	A	A	R	T	G	T	V	V	Y	L	E	P	L	N	R	Y	.	.	.
Query Conservation																																														.	.	.	.	.	.	.																											.	.	.
Alig confidence																			.	.	.	.	.	.	.	.	.	.	.	.	.	.														.	.	.	.	.	.	.																											.	.	.
Template Conservation																			.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	.	.	.	.	.	.	.	.	.	.	.	.	.	.	F	G	A	A	S	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P
Template Known Secondary structure											T	T		S					.	.	.	.	.	.	.	.	.	.	.	.	.	.				S									T	S	S		T	T	T															T	T									S	T	T		B	T
Template Predicted Secondary structure																			.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.															.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.
				152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.					.	.	.	.	.	.	.	.	210
Predicted Secondary structure		.	.																																																			.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence		.	.																																																			.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		.	.	Q	D	H	M	I	N	T	L	A	D	A	R	R	Y	I	V	E	N	D	L	K	H	V	Q	I	I	G	D	F	Y	H	M	N	I	E	E	D	N	L	A	Q	A	L	H	D	N	R	D	L	L	.	.	.	.	G	H	V	H	I	A	D	N	H	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation		.	.																																																			.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.																															.	.																			.	.	.	.										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																		.	.
Template Sequence		Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	I	S	L	G	D	T	I	G	.	.	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V
Template Known Secondary structure		T	T	B	S																T	T		S							T	T		.	.																		S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure																																		.	.
Template SS confidence
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.			.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
								211	.	.	.	.									.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.						.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.						.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	R	Y	Q	P	G	.	.	.	.	.	.	.	.	S	G	T	L	D	F	H	A	L	F	E	Q	L	R	A	D	N	Y	Q
Query Conservation		.	.	.	.	.	.						.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.						.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	A	S	G	N	L	A	T	E	D	L	V	Y	M	L	E	G	L	G	I	H
Template Known Secondary structure							B	T	T	S					T	T	S	S	S				B		B											T	T		B
Template Predicted Secondary structure
Template SS confidence
		254	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions