|   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | |
|
|
. | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | F | G | Q | D | K | A | I | E | A | L | T | E | A | I | K | M | A | R | A | G | L | G | H | E | H | K | P | V | G | S | F | L | F | A | G | P | T | G | V | G | K | T | E | V | T | V | Q | L | S | K | A | L | G | I | E | . |
. |
. |
L | L | R | F | D | M | S | E | Y | M | E | R | H | T | V | S | R | L | I | G | A |
Query Conservation |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   | . | . | . |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | L | G | E | A | N | S | F | L | E | V | L | E | Q | V | S | H | L | . |
. |
. |
. |
. |
. |
. |
A | P | L | D | K | P | V | L | I | I | G | E | R | G | T | G | K | E | L | I | A | S | R | L | H | Y | L | S | S | R | W | Q | G | P | F | I | S | L | N | C | A | A | L | N | E | N | L | L | D | S | E | L | F | G | H |
Template Known Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | T | T | S |
| S |
|  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  | T | S | T | T | T | T | S |
|  |  |  |  |  | G | G | G | S |
|  |  |  |  |  |  |  |  |  |
| B |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
537 | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | P | G | Y | V | G | F | D | Q | G | G | L | L | T | D | A | V | I | K | H | P | H | A | V | L | L | L | D | E | I | E | K | A | H | P | D | V | F | N | I | L | L | Q | V | M | D | N | G | T | L | T | D | N | N | G | R | K | A | D | F | R | N | V | V | L | V | M | T | T | N | A | G | V | R | E | T | E | R | K | S |
Query Conservation |   |
  |   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | K | R | H | P | G | R | F | E | R | A | D | G | G | T | L | F | L | D | E | L | A | T | A | P | M | M | V | Q | E | K | L | L | R | V | I | E | Y | G | E | L | E | R | V | G | G | S | Q | P | L | Q | V | N | V | R | L | V | C | A | T | N | A | D | L | P | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
| B |
|
|  |  |  |  | T | T | T | S |  |  |  |  |  | S | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |
|
|
| S | S | S |
|
|  |  |
|
|
|  |  |  |  |  |  | S | S |
|  |  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
|
|
|
|
|
  |
  |   |
617 | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | |
|
. | . | . | . | . | . | . | . | 690 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . | . |  |
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | L | I | H | Q | D | N | S | T | D | A | M | E | E | I | K | K | I | F | T | P | E | F | R | N | R | L | D | N | I | I | W | F | D | H | L | S | T | D | V | I | H | Q | V | V | D | K | F | I | V | E | L | Q | V | Q | L | D | Q | K | G | V | S | L | E | . |
. |
V | S | Q | E | A | R | N | W | L | A | E | K | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|
|   |
|
|   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|   | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | M | V | N | E | G | T | F | R | A | D | L | L | D | R | L | A | F | D | V | V | Q | L | P | P | L | R | E | R | E | S | D | I | M | L | M | A | E | Y | F | A | I | Q | M | C | R | E | I | K | L | P | L | F | P | G | F | T | E | R | A | R | E | T | L | L | N | . |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T | S | S |
|  |  |  |  |  |  |  |
| S |  |  |  |  |
|
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
|
| B |
|  |  |  |  |  |  |  |  |  | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
  |
  |   |
695 | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | D | R | A | M | G | A | R | P | M | A | R | V | I | Q | D | N | L | K | K | P |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|
|
|   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
Y | R | W | P | G | N | I | R | E | L | K | N | V | V | E | R | S | V | Y | R | H |
Template Known Secondary structure |   |
S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
  |