|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | |
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | V | L | V | T | G | A | T | S | G | L | G | R | N | A | V | E | F | L | C | Q | K | G | . |
I | S | V | R | A | T | G | R | N | E | A | M | G | K | L | L | E | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | G | A | E | F | V | P | A | D | L | T | E | L | V | S | S | Q | A | K | V | M | L | A | G | I | D | T |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |   |
| . |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
S | R | F | L | V | L | G | G | A | G | S | I | G | Q | A | V | T | K | E | I | F | K | R | N | P | Q | K | L | H | V | V | D | I | S | E | N | N | X | V | E | L | V | R | D | I | R | S | S | F | G | Y | I | N | G | D | F | Q | T | F | A | L | D | I | G | S | I | E | Y | D | A | F | I | K | A | D | G | Q | Y | D | Y |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |
|
|
| T | T | S |  |  |  |  |  |  |  |  |  |
|
|
|
| S |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
  |
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | W | H | C | S | S | F | T | S | P | W | G | T | Q | Q | . |
. |
. |
. |
. |
A | F | D | L | A | N | V | R | A | T | R | R | L | G | E | W | A | V | A | W | G | V | R | N | F | I | H | I | S | S | P | S | L | Y | F | D | Y | H | H | H | R | D | I | K | E | D | F | R | P | H | R | F | A | N | E | F | A | R | S | K |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |
|
|   |   |   |   |
|   |
|   |
|   |
|
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |
|
|   |
|
|
Template Sequence |   |
V | L | N | L | S | A | L | K | H | V | R | S | E | K | D | P | F | T | L | X | R | X | I | D | V | N | V | F | N | T | D | K | T | I | Q | Q | S | I | D | A | G | A | K | K | Y | F | C | V | S | T | D | K | A | A | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | N | X | X | G | A | S | K |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|
|
| G | G | G | G | S | S |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| S |
| S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 170 | . | . | . | . | . | . |
  |
  |   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | S | E | E | V | I | N | M | L | S | Q | A | N | P | Q | T | R | F | T | I | L | R | P | Q | S | L | F | G | P | H | D | K | V | F | I | P | R | L | A | H | M | M | H | H | Y | G | S | I | L | L | P | H | G | G | S | A | L | V | D | M | T | Y | Y | E | N | A | V | H | A | M | W | L | A | S | Q | E | A | C | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | I | X | E | X | F | L | X | R | K | . |
. |
. |
S | E | E | I | A | I | S | T | A | R | F | A | N | V | A | F | S | D | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | Q | K | N | Q | P | I | K | R | Y | F | V | T | P | Q | E | S | G | E | L | C | L | X | S | C | I | F | G | E | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | T | T | T | S |  |  |  |  |  |
|
|
|
| B | T | T |
| T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | T | T |
|
|
|
|
|
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
177 | . | . | 180 | . | . | . | . | . | . | |
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
  |
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | L | P | S | G | R | V | Y | N | I | T | N | G | E | H | R | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | D | . |
. |
. |
. |
I | F | F | P | K | D | X | A | R | F | D |
Template Known Secondary structure |   |
T |
| . | . | . | . |  |  |  |  |
|
|
| S | S |
| S |
Template Predicted Secondary structure |   |
|
| . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
251 | . | |
|
|
|
. | . | . | . | . | . | . | 260 | . | . | . |
  |