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Job DescriptionP75821
Confidence98.73%DateThu Jan 5 12:14:34 GMT 2012
Rank206Aligned Residues226
% Identity14%Templatec1fdvA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:17-beta-hydroxysteroid dehydrogenase; PDBTitle: human 17-beta-hydroxysteroid-dehydrogenase type 1 mutant2 h221l complexed with nad+
Resolution3.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.. .......30.........40.. .......50.........60.........70
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Query Sequence  VLVTGATSGLGRNAVEFLCQ. . . KGISVRATGRNEAMGKLLEK. . . . . . . . . MGAEFVPADLTELVSSQAKVMLAGIDTL
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Template Sequence  VLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEGRV
Template Known Secondary structure  S

SS
TT

SSGGG
TT

TTS

TT
T
TTS

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   5....10.........20.........30.........40.........50.........60.........70.........80....
 
   71........80.........90.........100.........110.........120.........130......... 140.........
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Query Sequence  WHCSSFTSPWGTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANE. FARSKAASEE
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Template Sequence  DVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEG
Template Known Secondary structure  S





BS
GGGS
TT


GGGTS

TT
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   85....90.........100.........110.........120.........130.........140.........150.........160....
 
   150.........160 .........170.........180.........190.........200.. .......210.........
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Query Sequence  VINMLSQANPQ. . TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSAL. . . . . . . . VDMTYYENAVHAMWLAS
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Template Sequence  LCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLALSKQVFREAAQNPEEVAEVFLTAL
Template Known Secondary structure  GGGT
S
BSSSTTGGGB

S

B
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   165....170.........180.........190.........200.........210.........220.........230.........240....
 
   220........
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Query Sequence  QEACDKLPS
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Template Sequence  RAPKPTLRY
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S
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   245....250...
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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