|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | V | G | I | V | F | G | G | K | S | A | E | H | E | V | S | L | Q | S | A | K | N | I | V | D | A | I | D | K | S | R | F | D | V | V | L | L | G | I | D | K | Q | G | Q | W | H | V | S | D | A | S | N | Y | L | L | N | A | D | D | P | A | H | I | A | L | R | P | S | A | T | S | L | A | Q | V | P | G | K | H |
Query Conservation |   |
  |   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
M | N | V | L | V | I | G | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | E | H | S | M | L | H | H | I | R | K | S | T | L | . |
L | N | K | L | F | I | A | P | G | R | E | G | M | S | G | L | A | D | I | I | D | I | D | I | N | S | T | I | E | V | I | Q | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | . |  |  |  |  |  |  |  |  |
|
| G | G | G | T | T | T | S |  |  |
|
|
|
| T | T |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | |
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | H | Q | L | I | D | A | Q | N | G | Q | P | L | P | T | V | D | V | I | F | P | I | V | H | G | T | L | G | E | D | G | S | L | Q | G | M | L | R | V | A | N | L | P | F | V | G | S | D | V | L | A | S | A | A | C | M | D | K | D | V | T | K | R | L | L | R | D | A | G | L | N | I | A | P | F | I | T | L | T | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | K | K | E | K | I | E | L | V | V | I | . |
. |
G | P | E | T | P | L | M | N | G | L | S | D | A | L | T | E | E | G | I | L | V | F | G | P | S | K | A | A | A | R | L | E | S | S | K | G | F | T | K | E | L | C | M | R | Y | G | I | P | T | A | K | Y | G | Y | F | V | D |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  | T | T |
|
|  |  |  |  | . | . |
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T |
|  |  |  | S |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
| B |
|
|  |  |  |  | S | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
58 | . | 60 | . | . | . | . | . | . | . | . | |
|
. | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . |
  |
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | R | H | N | I | S | F | A | E | V | E | S | K | L | G | L | P | L | F | V | K | P | A | N | Q | G | S | S | V | G | V | S | K | V | T | S | E | E | Q | Y | A | I | A | V | D | L | A | F | E | F | D | . |
. |
. |
. |
. |
. |
H | K | V | I | V | E | Q | G | I | K | G | R | E | I | E | C | A | V | L | G | N | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |   |
|   |
Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
| . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |
|
Template Sequence |   |
T | N | S | . |
. |
. |
. |
A | Y | K | F | I | D | K | H | K | L | P | L | V | V | K | A | D | G | L | A | Q | G | K | G | T | V | I | C | H | T | H | E | E | A | Y | N | A | V | D | A | M | L | V | H | H | K | F | G | E | A | G | C | A | I | I | I | E | E | F | L | E | G | K | E | I | S | F | F | T | L | V | D | G |
Template Known Secondary structure |   |
 |  |  | . | . | . | . |  |  |  |  |  |  |  | S |
| S | S |  |  |  |  |  | S | S |
|
| T | T | T | S |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| T | T | G | G | G | G | S | S |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
126 | . | . | |
|
|
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
  |
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
|
|
|
. | . | . | . | . | 290 | . | . | . | . | . | |
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | P | Q | A | S | T | C | G | E | I | V | L | T | S | D | F | Y | A | Y | D | T | K | Y | I | D | E | D | G | A | K | V | V | V | P | A | A | I | A | P | E | I | N | D | K | I | R | A | . |
. |
. |
. |
I | A | V | Q | A | Y | Q | T | L | G | C | . |
. |
A | G | M | A | R | V | D | V | F | L | T | P | E | N | E | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   | . | . | . | . |   |
|   |   |
|   |   |   |
|
|   | . | . |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   | . |   |
Template Sequence |   |
S | N | P | V | I | L | G | V | A | Q | D | Y | K | T | I | . |
G | D | N | N | K | G | P | N | T | G | G | M | G | S | Y | S | K | P | N | I | I | T | Q | E | M | E | H | I | I | I | Q | K | I | I | Y | P | T | I | K | A | M | F | N | M | N | I | Q | F | R | G | L | L | F | A | G | I | I | I | K | K | N | E | . |
P |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |
|
|  |  | . |  | G | G | G |  |  |  |  |
| S |
| S |  |  |  |  |
| T | T | S | S |
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T |  | . |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | |
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. |
  |
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | N | E | I | N | T | L | P | G | F | T | N | I | S | M | Y | P | K | L | W | Q | A | S | G | L | G | Y | T | D | L | I | T | R | L | I |
Query Conservation |   |
  |   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|   |
|   |
| . | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | L | L | E | Y | N | V | R | F | G | . |
. |
. |
D | P | E | T | Q | S | I | L | P | R | L | N | S | D | F | L | K | L | L | S | L | T | A |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |
|
| . | . | . | T | T |  |  |  |  |  | G | G | G | B |
| S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
280 | . | . | . | . | . | . | . | . | . | |
|
|
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
  |