|   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | V | G | I | V | F | G | G | K | S | A | E | H | E | V | S | L | Q | S | A | K | N | I | V | D | A | I | D | K | . |
. |
S | R | F | D | V | V | L | L | G | I | D | K | Q | G | Q | W | H | V | S | D | A | S | N | Y | L | L | N | A | D | D | P | A | H | I | A | L | R | P | S | A | T | S | L | A | Q | V | P | G | K |
Query Conservation |   |
  |
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   | . | . |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |
|   |   |   |   |
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | V | L | V | V | G | S | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | E | H | A | L | L | W | K | A | A | Q | S | P | R | V | K | R | L | Y | A | A | P | G | N | A | G | X | E | A | L | A | E | . |
. |
. |
. |
L | V | P | W | N | G | D | V | E | A | L | A | D | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|
|  |  |  |  |  |  |
|
| T | T | G | G | G | T | S |  | . | . | . | . |  |
|
|
|
| S |
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
| . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
83 | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | E | H | Q | L | I | D | A | Q | N | G | Q | P | L | P | T | V | D | V | I | F | P | I | V | H | G | T | L | G | E | D | G | S | L | Q | G | M | L | R | V | A | N | L | P | F | V | G | S | D | V | L | A | S | A | A | C | M | D | K | D | V | T | K | R | L | L | R | D | A | G | L | N | I | A | P | F | I | T | L | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |
|
|   | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | L | A | E | G | I | D | L | T | L | V | . |
. |
G | P | E | A | P | L | V | E | G | I | A | D | A | F | Q | A | R | G | L | L | L | F | G | P | T | Q | K | A | A | X | I | E | G | S | K | A | F | A | K | G | L | X | E | R | Y | G | I | P | T | A | R | Y | R | V | F | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |  | T |
|
|  |  |  |  | . | . |
| S | S |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T |
|
|  |  | S |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T |
|
|
| B |
|
|  |  |  |  | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
57 | . | . | 60 | . | . | . | . | . | . | . | |
|
. | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . |
  |
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | N | R | H | N | I | S | F | A | E | V | E | S | K | L | G | L | P | L | F | V | K | P | A | N | Q | G | S | S | V | G | V | S | K | V | T | S | E | E | Q | Y | A | I | A | V | D | L | A | F | E | F | . |
. |
D | H | K | V | I | V | E | Q | G | I | K | G | R | E | I | E | C | A | V | L | G | N | D | N | P | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
| . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | P | L | E | . |
. |
. |
. |
A | L | A | Y | L | E | E | V | G | V | P | V | V | V | K | D | S | G | L | A | A | G | K | G | V | T | V | A | F | D | L | H | Q | A | K | Q | A | V | A | N | I | L | N | R | A | E | G | G | E | V | V | V | E | E | Y | L | E | G | E | E | A | T | V | L | A | L | T | D | G | E | T | I |
Template Known Secondary structure |   |
S |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |
| T | T | S |
| S | S | T | T |
|  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |
|
|
|  |  |  |  |  |
|
|
| S |
|  |  |  |  |  |  |  |  | S | S | S |
|  |
Template Predicted Secondary structure |   |
|  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
124 | . | . | . | |
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | S | T | C | G | E | I | V | L | T | S | D | F | Y | A | Y | D | T | K | Y | I | D | E | D | G | A | K | V | V | V | P | A | A | . |
I | A | P | E | I | N | D | K | I | R | A | I | A | V | Q | A | Y | Q | T | . |
. |
. |
. |
. |
L | G | C | A | G | M | A | R | V | D | V | F | L | T | P | E | N | E | V | V | I | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   | . | . | . | . | . |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |
|
|
Template Sequence |   |
L | P | L | L | P | S | Q | D | H | K | R | L | L | . |
. |
D | G | D | Q | G | P | X | T | G | G | X | G | A | V | A | P | Y | P | X | D | E | A | T | L | R | R | V | E | E | E | I | L | G | P | L | V | R | G | L | R | A | E | G | V | V | Y | R | G | V | V | Y | A | G | L | X | L | T | R | E | G | . |
P | K | V | L |
Template Known Secondary structure |   |
 |  |
|
|
| B |  |  |
|
|  |  |  | . | . | T | T | T |  |  |  |  |
| S |
| S |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |
| S | S |
| . |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . |
  |
  |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | N | T | L | P | G | F | T | N | I | S | M | Y | P | K | L | W | Q | A | S | G | L | G | Y | T | D | L | I | T | R | L | I | E |
Query Conservation |   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |
| . | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | F | N | A | R | F | G | . |
. |
. |
D | P | E | A | Q | A | L | L | P | L | L | E | N | D | L | V | E | L | A | L | R | V | A | E |
Template Known Secondary structure |   |
 |  |  | S | S |
|
| . | . | . | T | T |  |  |  |  |  | T | T | T | B |
| S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
277 | . | . | 280 | . | . | . | |
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
  |