Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	I	R	N	V	L	L	A	F	M	I	C	S	G	M	T	L	L	G	G	C	S	S	V	M	S	H	T	G	G	K	E	G	T	Y	P	G	T	R	A	S	A	T	M	I	G	D	D	E	T	N	W	G	T	K	S	L	A	I	L
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110
Sequence		D	M	P	F	T	A	V	M	D	T	L	L	L	P	W	D	V	F	R	K	D	S	S	V	R	S	R	V	E	K	S	E	A	N	A	Q	A	T	N	A	V	I	P	P	A	R	M	P	D	N
Secondary structure
SS confidence
Disorder																					?		?	?	?				?						?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2pxg chain A Region: 18 - 35 Aligned: 17 Modelled: 18 Confidence: 14.2% Identity: 12% PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein; PDBTitle: nmr solution structure of omla Phyre2 PDB 3sqg chain G Region: 30 - 66 Aligned: 35 Modelled: 37 Confidence: 11.2% Identity: 31% PDB header:transferase Chain: G: PDB Molecule:methyl coenzyme m reductase, alpha subunit; PDBTitle: crystal structure of a methyl-coenzyme m reductase purified from black2 sea mats Phyre2 PDB 1zkd chain A domain 1 Region: 21 - 37 Aligned: 17 Modelled: 17 Confidence: 9.9% Identity: 12% Fold: S-adenosyl-L-methionine-dependent methyltransferases Superfamily: S-adenosyl-L-methionine-dependent methyltransferases Family: RPA4359-like Phyre2 1 c2pxgA_ 2 c3sqgG_ 3 d1zkda1

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2pxgA_ 14.2 12 PDB header:membrane protein Chain: A: PDB Molecule:outer membrane protein; PDBTitle: nmr solution structure of omla 2 c3sqgG_ 11.2 31 PDB header:transferase Chain: G: PDB Molecule:methyl coenzyme m reductase, alpha subunit; PDBTitle: crystal structure of a methyl-coenzyme m reductase purified from black2 sea mats 3 d1zkda1 9.9 12 Fold:S-adenosyl-L-methionine-dependent methyltransferases Superfamily:S-adenosyl-L-methionine-dependent methyltransferases Family:RPA4359-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0