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Job DescriptionP42588
Confidence99.95%DateThu Jan 5 12:01:35 GMT 2012
Rank64Aligned Residues348
% Identity15%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   80.........90.........100.........110... ......120.........130.........140.........150..
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Query Sequence  QGQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAK. . . . . . . QPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTE
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Template Sequence  ENAIYFLGNS. . . . . . LGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTV
Template Known Secondary structure 
B

BTTT......S

B
TTGGGGGTSSSS
GGGTTGGGT

GGG
S
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   66...70..... ....80.........90.........100.........110.........120.........130.........
 
   153......160.........170.........180.........190....... ..200.........210.........220.........230.
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Query Sequence  SVEAALKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFR. KPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDD
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Template Sequence  NLHLLMLSFFKPTP. . KRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEG. . . DS
Template Known Secondary structure 



S..SS
TT

TT




TT
SS

G...GG
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   140.........150... ......160.........170.........180.........190.........200.........210.. ..
 
   232.......240.........250.........260.........270.........280.........290.........300.........310.
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Query Sequence  VAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGA
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Template Sequence  IAVILFSGVHFYTGQHFN. . . . IPAITKAGQAKGCYVGFDLAHAVG. . . NVELYLHDWGVDFACWCSYKYLNAGAGGIAG
Template Known Secondary structure  SB
TTT
BB

....TT

TTTTT...TS


T


SSSTT


TT


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   215....220.........230.. .......240.........250...... ...260.........270.........280.......
 
   312.......320........ .330.........340.........350.........360.....
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Query Sequence  TIATEEVFSVLFDNPFL. . . . . . . . . . . . . . . . . . . . . . . . . . HTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDM
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Template Sequence  AFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGY
Template Known Secondary structure 
GGGTTTS

SS

GGGB
TT

S


B
SSGGGG

S



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   288.290.........300.........310.........320.........330.........340.........350.........360.......
 
   366...370.........380.. .......390.........400.........410.........420......... 430.........440..
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Query Sequence  LLDGFRQLAREYPDLVQ. . EARGKGMLMAIEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEP. PLTLTIEQCELVI
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Template Sequence  LEYLIKHNYGVV. NIITPSHVEERGCQLTITFSVP. . NKDVFQELEKRGVVCDKRN. . PNGIRVAPVPLYNSFHDVYKFT
Template Known Secondary structure 


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S
SSGGGB
S


T..T

TTT
T..TTB

TTT

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   368.370......... 380.........390.........400. ........410.........420 .........430.........440..
 
   443......450
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Query Sequence  KAARKALA
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Template Sequence  NLLTSILD
Template Known Secondary structure  T
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   452.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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