|   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
|
|
. | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
. | . | . | . | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | Q | E | F | I | D | C | L | G | G | F | G | I | F | N | V | G | H | R | N | P | V | V | V | S | A | V | Q | N | Q | L | A | K | . |
. |
. |
Q | P | L | H | S | Q | E | L | L | D | P | L | R | A | M | L | A | K | T | L | A | A | L | T | P | G | K | L | . |
. |
. |
K | Y | S | F | F | C | N | S | G | T | E | S |
Query Conservation |   |
|
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |
|   |   |   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |
|   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|   |
|   |   |   |   | . | . | . |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
Template Sequence |   |
G | P | L | P | L | I | N | X | A | V | G | I | P | D | G | P | T | . |
. |
. |
P | Q | G | I | I | D | H | F | Q | K | A | L | T | I | P | E | N | Q | K | Y | G | A | F | H | G | K | E | A | F | K | Q | A | I | V | D | F | Y | Q | R | Q | Y | N | V | T | L | D | K | E | D | E | V | C | I | L | Y | G | T | K | N | G |
Template Known Secondary structure |   |
| S | S |
|
|  |  |
|
|
|
| S |
| S | S |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  | S |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| T | T | T | S |  |  |  |  | S | S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
. | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | A | A | L | K | L | A | K | A | Y | Q | S | P | R | G | K | F | T | F | I | A | T | S | G | A | F | H | G | K | S | L | G | A | L | S | A | T | A | K | S | T | F | R | K | P | F | M | P | L | L | P | G | F | R | H | V | P | F | G | N | I | E | A | M | R | T | A | L | N | E | C | K | K | T | G | D | D | V | A |
Query Conservation |   |
  |
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |   | . | . | . | . | . |   |
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
L | V | A | V | P | T | C | V | I | N | . |
. |
. |
. |
. |
P | G | D | Y | V | L | L | P | D | P | G | Y | T | D | Y | L | A | G | V | L | L | A | D | G | K | P | V | P | L | N | L | E | P | P | . |
. |
. |
. |
. |
. |
. |
H | Y | L | P | D | W | S | K | V | D | S | Q | I | I | . |
. |
. |
. |
. |
. |
D | K | T | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| . | . | . | . | . | T | T |
|  |  |  |  |  |  | S |
|
| S | S |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|
| T | T | . | . | . | . | . | . | . | T |
|
|
|
| G | G | G | S |
|  |  |  |  | . | . | . | . | . | . |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
102 | . | . | . | . | . | . | . | 110 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
160 | . | . | . |
  |
  |   |
234 | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | |
|
|
|
. | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | I | L | E | P | I | Q | G | E | G | G | V | I | L | P | P | P | G | Y | L | T | A | V | R | K | L | C | D | E | F | G | A | L | M | I | L | D | E | V | Q | T | G | M | G | R | T | G | K | . |
. |
. |
. |
M | F | A | C | E | H | E | N | V | Q | P | D | I | L | C | L | A | K | A | L | G | G | G | V | M | P | I |
Query Conservation |   |
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|   |
|
|   |
|   | . | . | . | . |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|   |   |
|   |
|   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
| . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
Template Sequence |   |
L | I | Y | L | T | Y | P | N | N | P | T | G | . |
S | T | A | T | K | E | V | F | D | E | A | I | A | K | F | K | G | T | D | T | K | I | V | H | D | F | A | Y | G | A | F | G | F | D | A | K | N | P | S | I | L | A | S | E | N | G | K | D | V | A | I | E | I | Y | S | L | S | K | G | Y | N | X | S | G | F | R | V |
Template Known Secondary structure |   |
 |  |  |  |
| S | S |
| T | T | T |
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |
| T | T | T | T |
| B | S | S | S |
|
|
|
| G | G | G | S | T | T |  |  |  |  |  |  |  |  |  |  | S | T | T | T | T | T |
| G | G | G |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | |
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | T | I | A | T | E | E | V | F | S | V | L | F | D | N | P | F | L | H | T | T | T | F | G | G | N | P | L | A | C | A | A | A | L | A | T | I | N | V | L | L | E | Q | N | L | P | A | Q | A | E | Q | K | G | D | M | L | L | D | G | F | R | Q | L | A | R | E | Y | P | D | L | V | Q | E | A | R | G | K | G | M |
Query Conservation |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
G | F | A | V | G | N | K | D | X | I | Q | A | L | K | K | Y | Q | T | H | T | N | A | G | X | F | G | A | L | Q | D | A | A | I | Y | A | L | N | H | Y | D | D | F | L | E | E | Q | S | N | V | F | K | T | R | R | D | R | F | E | A | X | L | A | K | . |
. |
. |
. |
. |
A | D | L | P | F | V | H | A | K | G | G | I |
Template Known Secondary structure |   |
 |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
|
|  |  |
|
|
| B | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 310 | . | . | . | . | . | . | . |
  |
  |   |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | |
. | . | . | . | . | . | . | . | 420 | . | . | . | |
|
|
|
. | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | M | A | I | E | F | V | D | N | E | I | G | Y | N | F | A | S | E | M | F | R | Q | . |
R | V | L | V | A | G | T | L | N | N | A | K | . |
. |
. |
. |
T | I | R | I | E | P | P | L | T | L | T | I | E | Q | C | E | L | V | I | K | A | A | R | K | A | L | A | A |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |
|
|   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |
|
|
|   |
|   |
|   |   |
|   |
|
|
|
|   |   |
|   |   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   | . | . |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
Y | V | W | L | E | T | P | P | G | Y | D | S | E | Q | F | E | Q | F | L | V | Q | E | K | S | I | L | V | A | P | G | K | P | F | G | E | N | G | N | R | Y | V | R | I | S | L | A | . |
. |
L | D | D | Q | K | L | D | E | A | A | I | R | L | T | E | L | A | Y | L |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | S | G | G | G |
| G | G | G | T | T |  |  |  |  |  |
|
| . | . | S |
| T | T |  |  |  |  |  |  |  |  |  |  | G | G | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
318 | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . |
  |