|   |
424 | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | |
|
|
. | . | . | |
480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
| . |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | N | S | A | L | V | S | I | N | P | Q | N | G | A | V | M | A | L | V | G | G | F | D | F | N | Q | S | K | F | N | R | A | T | Q | A | L | R | Q | V | G | S | N | I | K | P | F | L | Y | T | A | A | M | . |
. |
. |
D | K | G | . |
L | T | L | A | S | M | L | N | D | V | P | I | S | R | W | D | A | S | A | G |
Query Conservation |   |
  |   |
|   |
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|
| . | . | . |
|   |
| . |   |
|   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
Template Sequence |   |
G | L | T | G | S | F | L | V | R | D | L | Y | T | G | E | E | L | G | I | D | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | E | L | P | T | A | S | L | V | K | L | P | L | A | L | A | T | L | E | R | I | R | L | G | E | V | D | G | A | Q | Q | I | E | V | A | P | G | R | I | T | T | P | G | P | . |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | S | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |
| G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
| T | T |
|  |  |  |  |
|
|
|
|
|
| S | S | S |
| . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | |
  |
  |   |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 560 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
S | D | W | Q | P | K | N | S | P | P | Q | Y | A | G | P | I | R | L | R | Q | G | L | G | Q | S | K | N | V | V | M | V | R | A | M | R | A | M | G | V | D | Y | A | A | E | Y | L | Q | R | F | G | F | P | A | Q | N | I | V | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | E | S | L | A | L | G | S |
Query Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |   |
|
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | G | L | S | R | F | R | H | P | A | R | V | A | V | D | D | L | L | Y | L | S | T | S | V | S | D | G | T | A | S | D | A | L | F | E | I | T | P | P | A | Q | V | E | Q | M | V | R | E | W | G | F | R | D | L | T | V | R | H | S | M | R | E | L | G | T | S | G | R | G | H | R | V | P | Q | L | D | V | A | R | A |
Template Known Secondary structure |   |
| G | G | G | G |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|
|
|
| S |
| T | T |
|
|
|
| S | B | T | T |
| S | S | G | G | G | B | T | T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
566 | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | S | F | T | P | M | Q | V | A | R | G | Y | A | V | M | A | N | G | G | F | L | V | D | P | W | F | I | S | K | I | E | N | D | Q | G | G | V | I | F | E | A | K | P | K | V | A | C | P | E | C | D | I | P | V | I | Y | G | D | T | Q | K | S | N | V | L | E | N | N | D | V | E | D | V | A | I | S | R | E | Q | Q |
Query Conservation |   |
  |   |
|
|
|
|   |
|
|   |
|
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
N | T | G | T | A | R | A | F | V | D | L | L | E | A | L | W | A | P | V | L | T | G | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
646 | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | S | V | P | M | P | Q | L | E | Q | A | N | Q | A | L | V | A | K | T | G | A | Q | E | Y | A | P | H | V | I | N | T | P | L | A | F | L | I | K | S | A | L | N | T | N | I | F | G | E | P | G | W | Q | G | T | G | W | R | A | G | R | D | L | Q | R | R | D | I | G | G | K | T | G | T | T | N | S | S | K | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | P | E | P | A | A | R | L | R | E | L | M | A | A | N | L | L | R | H | . |
. |
. |
. |
R | L | A | P | D | F | . |
. |
A | S | D | A | A | T | W | S | S | K | T | G | T | L | L | N | L | R | H |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | . | . | . | . | S | S |  |  |  |  | . | . |
| B | T | T |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
|
|
. | 240 | . | . | . | . | |
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
  |
  |   |
726 | . | . | . | 730 | . | . | |
|
|
. | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | W | F | S | G | Y | G | . |
. |
. |
P | G | V | V | T | S | V | W | I | G | F | D | D | H | R | R | N | L | G | H | T | T | A | S | G | A | I | K | D | Q | I | S | G | Y | E | G | G | A | K | S | A | Q | P | A | W | D | A | Y | M | K | A | V | L | E |
Query Conservation |   |
|
|
|
|
|
|
| . | . | . |
|   |   |   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |
Template Sequence |   |
E | V | G | V | V | E | H | A | D | G | Q | V | F | A | V | A | V | L | T | E | S | Q | V | P | A | D | S | Q | P | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | E | A | L | M | A | Q | V | A | R | R | L | R | D | R | L | R | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  | S | S |
|
| S |
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
  |