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Job DescriptionP02918
Confidence100.00%DateThu Jan 5 10:57:34 GMT 2012
Rank5Aligned Residues421
% Identity26%Templatec2jciA_
PDB info PDB header:drug-binding proteinChain: A: PDB Molecule:penicillin-binding protein 1b; PDBTitle: structural insights into the catalytic mechanism and the2 role of streptococcus pneumoniae pbp1b
Resolution2.5 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   188.190.........200.........210.........220.........230.........240.........250.........260.......
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Query Sequence  VDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEM
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Template Sequence  ISEITYSDGTVIASIDYLY. . . . . . . . FTTLAEAQERMYDYLAQRDNVSAKELKNE. . . . . . . . . . . . . . . . . . . . . . . A
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TTS


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T
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   105....110.........120... ......130.........140.........150.. .
 
   268.270.........280.........290.........300.........310.........320.........330.........340.......
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Query Sequence  VRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNNKITDTLKALPTYG
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Template Sequence  TQKFYRDLAAKEIENGGYKITTTIDQKIHSAMQSAVADYGYLLDDGTG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  S

S

GGGG

SSS................................
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   371........380.........390.........400.........410........
 
   348.350.........360.........370.........380.........390.........400.........410.........420.......
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Query Sequence  PLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNS
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RVEV
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   419420..
 
   428.430.........440.........450.........460.........470. ........ 480.........490.........500.....
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Query Sequence  ALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFL. YTAAMDKG. LTLASMLNDVPISRWDASAGSDWQPK
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Template Sequence  GNVLMDNQTGAILGFVGGRNYQENQNNHAFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANG. . . . . NPIM
Template Known Secondary structure  TTT
B

S
TTT



TTTT

B

GGGGTTTS

TT

S

B
TTS.....
B

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   423......430.........440.........450.........460.........470.........480.........490... ....
 
   506...510.........520.........530......... 540.........550.........560... ......570.........580..
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Query Sequence  NSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVD. . YAAEYLQRFGFPAQNIVHTESLAL. GSASFTPMQVARGYAVMAN
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Template Sequence  YANSKGTGMMTLGEALNYSWNIPAYWTYRMLRENGVDVKGYMEKMGYEI. PEYGIESLPMGGGIEVTVAQHTNGYQTLAN
Template Known Secondary structure  BTTB


ST
STT

TT


.S



TTGGGTTT

B
T
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   498.500.........510.........520.........530.........540...... ...550.........560.........570......
 
   583......590.........600.........610.........620.........630.........640.........650.........660..
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Query Sequence  GGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALV
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Template Sequence  NGVYHQKHVISKIEAADGRVVYEYQDK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT


BS
TTS




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   577..580.........590.........600...
 
   663......670.........680.........690.........700......... 710.........720.........730.....
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Query Sequence  AKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQ. . . . . . . RRDIGGKTGTTNSSKDAWFSGYGPGV
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Template Sequence  . . . . . . . . PVQVYSKATATIMQGLLREVL. . . . . SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRL
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S
.....TTSS


TS


GGG

SS
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   604.....610.........620.... .....630.........640.........650.........660.........670
 
   736...740.........750.........760.........770.........780......... 790.........800.........810.
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Query Sequence  VTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVP. . . . EQPLTPPPGIVTVNIDRSTGQL
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Template Sequence  TLGGWIGHDDN. . . . . . . . . . . . . . . HSLSQQAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQK
Template Known Secondary structure 
TT
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TTTTTTSTTSS







TT
TTTSSB
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   671........680. ........690.........700.........710.........720.........730.....
 
   812.... ...820.........830....
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Query Sequence  ANGGN. . . . . . . . . . . SREEYFIEGTQPTQQAVH
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Template Conservation 
                 
               
Template Sequence  PGKVSVEGKEVEVTGSTVTSYWANKSGAPATSYR
Template Known Secondary structure 

SSS
S
SSSS


B

TT
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   736...740.........750.........760.........
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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