|   |
1 | . | . | . | . | . | . | . | . | 10 | . | |
|
|
|
. | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | S | I | L | I | E | K | P | N | Q | . |
. |
. |
. |
L | A | I | V | E | R | E | I | P | T | P | S | A | G | E | V | R | V | K | V | K | L | A | G | I | C | G | S | D | S | H | I | Y | R | G | H | N | P | . |
F | A | K | Y | P | R | V | I | G | H | E | F | F | G | V | I | D | A | V | G | E | G | V | E | S | A |
Query Conservation |   |
|
|
|
|
|   |   |   |   |   |   | . | . | . | . |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   | . |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
V | R | A | L | V | Y | G | H | H | G | D | P | A | K | V | V | E | L | K | N | L | E | L | A | A | V | R | G | S | D | V | R | V | K | M | L | A | A | P | I | N | P | S | D | I | N | M | I | Q | G | N | Y | G | L | L | P | E | L | P | A | V | G | G | N | E | G | V | A | Q | V | V | A | V | G | S | N | V | T | G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |
| S |
|  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | T |
| S | S |
|
|
|
| S | S |  |  |
|
| S |
|
|  |  |  |  |  |  |  |
| T | T |
|
| S |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
43 | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | V | G | E | R | V | A | V | D | P | V | V | S | C | G | H | C | Y | P | C | S | I | G | K | P | N | V | C | T | T | L | A | V | L | G | V | H | A | D | G | G | F | S | E | Y | A | V | V | P | A | K | N | A | W | K | I | P | E | A | V | A | D | Q | Y | A | V | M | I | E | P | F | T | I | A | A | N | V | T | G | H |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | P | G | D | W | V | I | P | A | N | A | G | L | G | T | W | R | T | E | A | V | F | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | L | I | Q | V | P | S | D | I | P | L | Q | S | A | A | T | L | G | V | N | P | C | T | A | Y | R | M | L | M | D | F |
Template Known Secondary structure |   |
| T | T |
|  |  |  |  | S | S | T | T | S |
|
|
| B | S |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | S |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | S | S |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
123 | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
  |
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | |
|
|
|
. | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | P | T | E | N | D | T | V | L | V | Y | G | A | G | P | I | G | L | T | I | V | Q | V | L | K | G | V | Y | N | V | K | N | V | I | V | A | D | R | I | . |
. |
. |
. |
D | E | R | L | E | K | A | K | E | S | G | A | D | W | A | I | N | N | S | Q | T | P | L | G | E | I | F | T | E | K | G | I | K | P | T | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | Q | L | Q | P | G | D | S | V | I | Q | N | A | S | N | S | G | V | G | Q | A | V | I | Q | I | A | A | A | L | G | L | R | T | I | N | V | V | R | D | R | P | D | I | Q | K | L | S | D | R | L | K | S | L | G | A | E | H | V | I | T | E | E | E | L | R | R | P | E | M | K | N | F | F | K | D | M | P | Q | P | R |
Template Known Secondary structure |   |
S |
|
|
| T | T |
|  |  |  |  | S | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  |  |  |  |  | S | S | S | T | T | T | T | T | T | T | S | S |
|
|
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
  |
  |   |
232 | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | D | A | A | C | H | P | S | I | L | K | E | A | V | T | L | A | S | P | A | A | R | I | V | L | M | . |
G | F | S | S | E | P | S | E | V | I | Q | Q | G | I | T | G | K | E | L | S | I | F | S | S | R | L | N | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | K | F | P | I | V | I | D | W | L | S | K | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
L | A | L | N | C | V | G | G | K | S | S | T | E | L | L | R | Q | L | A | R | G | G | T | M | V | T | Y | G | G | M | A | K | Q | P | V | V | A | S | V | S | L | L | I | F | K | D | L | K | L | R | G | F | W | L | S | Q | W | K | K | D | H | S | P | D | Q | F | K | E | L | I | L | T | L | C | D | L | I | R | R | G |
Template Known Secondary structure |   |
 |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |
|
|
|
| T | T | S |
| B |
|
|
|  |  |  |  |  |  | S |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | K | P | E | K | L | I | T | H | T | F | D | F | Q | H | V | A | D | A | I | S | L | F | E | Q | D | Q | K | H | C | C | K | V | L | L | T | F |
Query Conservation |   |
  |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   | . | . |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   | . |
|
|
|
|
|   |
|
Template Sequence |   |
Q | L | T | A | P | . |
. |
A | C | S | Q | V | P | L | Q | D | Y | Q | S | A | L | E | A | S | M | K | P | F | I | S | . |
S | K | Q | I | L | T | M |
Template Known Secondary structure |   |
S | S |
|
|
| . | . |
|  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |
| T | T |
|
| . | S |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
339 | 340 | . | . | . | |
|
. | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | |
. | . | . | 370 | . | . | . |
  |