|   |
482 | . | . | . | . | . | . | . | 490 | . | |
|
|
|
. | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | L | K | V | M | M | N | V | G | . |
. |
. |
. |
N | P | D | R | A | F | D | F | A | C | L | P | N | E | G | V | G | L | A | R | L | E | F | I | I | N | R | M | I | G | V | H | P | R | A | L | L | E | F | D | D | Q | E | P | Q | L | Q | N | E | I | R | E | M | M | K | G | F | D | S | P | R | E | F | Y | V | G |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|
|
|   |   |
|   |   |   |
Template Sequence |   |
R | R | T | S | I | I | G | T | I | G | P | K | T | N | N | P | E | T | L | V | A | L | R | K | A | G | L | N | I | V | R | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | F | S | H | G | S | Y | E | Y | H | K |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |
|
| T | T | T |
| S |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | T | T | S |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 60 | . |
  |
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | T | E | G | I | A | T | L | G | A | A | F | Y | P | K | R | V | I | V | R | L | S | D | F | K | S | N | E | Y | A | N | L | V | G | G | E | R | Y | E | P | D | E | E | N | P | M | L | G | F | R | G | A | G | R | Y | V | S | D | S | F | R | D | C | F | A | L | E | C | E | A | V | K | R | V | R | N | D | M | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|   |
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |
|   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|   |
|
|
|
|
|   |   |
|
|   |   |
|   |   |   | . | . |
Template Sequence |   |
S | V | I | D | N | A | R | K | S | E | E | L | Y | P | G | R | P | L | A | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | T | K | G | P | A | L | S | E | K | D | K | E | D | L | R | F | G | V | K | N | . |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
| S |
|
| B |
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
|
  |
  |   |
638 | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | N | V | E | I | M | I | P | F | V | R | T | V | D | Q | A | K | A | V | V | E | E | L | A | R | Q | G | L | K | R | G | E | N | G | L | K | I | I | M | M | C | E | I | P | S | N | A | L | L | A | E | Q | F | L | E | Y | F | D | G | F | S | I | G | S | N | D | M | T | Q | L | A | L | G | L | D | R | D | S | G |
Query Conservation |   |
  |   |   |
|   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
. |
|
|
|   |
|   |
|
|
|
|   |
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   | . | . | . | . | . |   |   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   | . | . | . | . | . | . |
Template Sequence |   |
. |
G | V | H | M | V | F | A | S | F | I | R | T | A | N | D | V | L | T | I | R | E | V | L | G | E | Q | G | K | D | . |
. |
. |
. |
. |
V | K | I | I | V | K | I | E | N | Q | Q | G | V | N | N | F | D | E | I | L | K | V | T | D | G | V | M | V | A | R | G | D | L | G | I | E | I | P | A | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | T |
|
|  |  |
|
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T | T | . | . | . | . | . | S |
|
|  |  |  |  |
| S |  |  |  |  | T | T |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
|  | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
|
|
  |
  |   |
718 | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 760 | . | . | . | . | |
|
. | . | . | . | . | 770 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  | . | . |  |  |  |
|
|
|
|  |  |  |  |
|  | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
V | V | S | E | L | F | D | E | R | N | D | A | V | K | A | L | L | S | M | A | I | R | A | A | K | K | Q | G | K | Y | V | G | I | C | G | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | P | S | D | H | E | D | F | A | A | W | . |
. |
L | M | E | E | G | I | D | S | L | S | L | N | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|
|
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   | . | . |
|   |   |
|
|
|   |   |   |
|   |   |
| . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
| . |
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |
|
|
| . |
|
|
|   |
|
|   |
|
|
|   |
|
|   |
|   |
|
|
|
|   |
|
|
|   |
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | V | L | A | V | Q | K | K | L | I | A | K | S | N | L | A | G | K | P | V | I | C | A | T | Q | M | L | E | S | M | T | Y | N | P | R | P | T | R | . |
A | E | V | S | D | V | G | N | A | I | L | D | G | A | D | C | V | M | L | S | G | E | T | A | K | G | N | Y | P | I |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S | S | S | G | G | G | G | T |
| S | S |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |
|
| S |  |  |  |  | S |
| S |
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | |
. | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |
  |   |
778 | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | T | V | V | Q | T | W | L | S | L | A | E | L | K | K |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
Template Sequence |   |
N | A | V | T | T | M | A | E | T | A | V | I | A | E | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
343 | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
  |