|   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | |
. | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | V | A | G | V | D | M | G | A | T | H | I | R | F | C | L | R | T | A | E | G | . |
E | T | L | H | C | E | K | K | R | T | A | E | V | I | A | P | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | S | G | I | G | E | M | I | D | E | Q | L | R |
Query Conservation |   |
  |   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |
|   |
|   |   |
| . |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
N | V | P | I | I | M | D | N | G | T | G | Y | S | K | L | G | Y | A | G | N | D | A | P | S | Y | V | F | P | T | V | I | A | T | R | T | E | D | L | D | F | F | I | G | N | D | A | L | K | K | A | S | A | G | Y | S | L | D | Y | P | I | R | H | G | Q | I | E | N | W | D | H | M | E | R | F | W | Q | Q | S | L | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  |  | T | T | S | S | S |
| S |  |  |  |  |
|
|  |  |
|
|
|
| S | S |
|
|  |  | T |  |  |  |  |  | T |  |  |  |  |
|
|
|
|
| S |  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
. | . | . | . | . | . | . | . | 120 | . | . | . | |
|
. | . | . | . | . | . | 130 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |  |  |
|
|  |  |  |  |  |  |  |  | . | . |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | N | A | R | C | H | G | L | V | M | G | F | P | A | L | V | S | K | D | K | R | T | I | I | S | T | P | N | L | P | L | T | A | A | D | L | Y | D | L | A | D | K | L | E | N | T | L | N | C | P | V | E | . |
F | S | R | D | V | N | L | Q | L | S | W | D | . |
. |
V | V | E | N | R | L | T | Q | Q | L | V | L |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   | . |
|   |
|
|   |   |   |
|
|   |
|
| . | . |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
K | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | R | C | E | P | E | D | H | Y | F | L | L | T | E | P | P | L | N | P | P | E | N | R | E | N | T | A | E | I | M | F | E | S | F | N | C | A | G | L | Y | I | A | V | Q | A | V | L | A | L | A | A | S | W | T | S | S | K | V | T | D | R | S | L | T | G | T |
Template Known Secondary structure |   |
T | T | . | . | . | . | . | . | . | . | . | . | . | . | S |
|
|
| G | G | G |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G | G | S | T | T | T |
| S |
|
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . |
  |
  |   |
136 | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
A | A | Y | L | G | T | G | M | G | F | A | V | W | M | N | G | A | P | W | T | G | A | H | G | V | A | G | E | L | G | H | I | P | L | G | D | M | T | Q | H | C | A | C | G | N | P | G | C | L | E | T | N | C | S | G | M | A | L | R | R | W | Y | E | Q | Q | P | R | N | Y | P | L | R | D | L | F | V | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
|
|
|   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | V | D | S | G | D | G | V | T | H | I | I | P | V | A | E | G | Y | V | I | G | S | S | I | K | T | M | P | L | A | G | R | D | V | T | Y | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | Q | S | L | L | R | L | K | T | A | E | R | I | K | E | E | C | C | Y | V | C | P | D | I | V | K | E | F | S | R | F | D |
Template Known Secondary structure |   |
 |  |  |  | S | S | S |
|  |  |  |  |  |  |  | T | T |  |  |
| G | G | G |
|
|  |  | S |
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| S |
|  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | |
|
|
. | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | A | E | N | A | P | F | V | Q | S | L | L | E | N | A | A | R | A | I | A | T | S | . |
. |
. |
I | N | L | F | D | P | D | A | V | I | L | G | G | G | V | M | D | M | P | A | F | P | R | E | T | L | V | A | M | T | Q | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
| . | . | . |   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|   |
|   |
| . |
|
|
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
R | L | K | Y | A | S | I | D | V | G | F | E | R | F | L | A | P | E | I | F | F | N | P | E | I | A | S | S | D | F | L | T | P | L | P | E | L | V | D | N | V | V | Q | S | S | P | I | D | V | R | K | G | L | Y | K | N | I | V | L | S | G | G | S | T | L | F | . |
K | N | F | G | N | R | L | Q | R | D | L | K | R |
Template Known Secondary structure |   |
|
|
| B |
|
|
| B |
|
| T |  |  |  |  | S | G | G | G | G | T |
| G | G | G | T |
| S | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |
|  |  |  |  | S | G | G | G |
| S | . | T | T | T | T |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
. | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |
  |   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | L | R | R | P | L | P | H | Q | V | V | R | F | I | A | A | S | S | S | D | F | N | G | A | Q | G | A | A | I | L | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |
|
Template Sequence |   |
I | V | . |
. |
D | E | R | G | V | D | V | N | V | I | S | H | K | R | Q | R | N | A | V | W | F | G | G | S | L | L | A |
Template Known Secondary structure |   |
 |  | . | . | T | T |
|
|
|
|
|
|  |  |
|
| T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
353 | . | |
|
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
  |