|   |
1 | . | |
|
|
. | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
. | . | . | . |
Predicted Secondary structure |   |
|
| . | . | . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
Query SS confidence |   |
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
M | S | . |
. |
. |
K | K | I | A | V | I | G | E | C | M | I | E | L | S | E | K | G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | V | K | R | G | F | G | G | D | T | L | N | T | S | V | Y | I | A | R | Q | . |
V | D | P | A |
Query Conservation |   |
|   | . | . | . |   |   |
|
|   |
|
|   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
| . |   |   |   |   |
Alig confidence |   |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |
|   |
|
Template Sequence |   |
M | A | S | A | P | L | R | V | Y | V | Q | C | N | P | L | L | D | V | S | A | H | V | S | D | E | F | L | V | K | Y | G | L | E | R | G | T | A | I | L | L | S | E | R | Q | K | G | I | F | D | D | I | E | K | M | P | N | V | R | Y | V | P | G | G | S | G | L | N | V | A | R | V | A | Q | W | M | Q | Q | A | Y | K |
Template Known Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |
|
| G | G | G | T | T |  |  |  |  |  | T | T | S | T | T |
|  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | T | V | H | Y | V | T | A | L | G | T | D | S | F | S | Q | Q | M | L | D | A | W | H | G | E | N | V | D | T | S | L | T | Q | R | M | E | N | R | L | P | G | L | Y | Y | I | E | T | D | S | T | G | E | R | T | F | Y | Y | W | R | N | E | A | A | A | K | F | W | L | E | S | E | Q | S | A | A | I | C | E | E |
Query Conservation |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | K | F | V | T | Y | V | G | C | I | A | D | D | R | Y | G | K | V | L | K | E | A | A | E | H | E | G | I | V | M | A | V | E | H | T | T | K | A | G | S | G | A | C | A | V | C | I | T | . |
. |
G | K | E | R | T | L | V | A | D | L | G | A | A | . |
N | H | L | S | S | E | H | M | R | S | P | A | V | V | R | A |
Template Known Secondary structure |   |
T | S | S |  |  |  |  |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |
|
|  |  |  | S | S | S |
|
|
|  |  |  |  |  |  |  | . | . | T | T |  |  |  |  |  |  |  |
| G | G | G | . | G | G |
|
|  |  |  |  |  | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | |
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . |
  |
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | N | F | D | Y | L | Y | L | S | G | I | S | L | A | I | L | S | P | T | S | R | E | K | L | L | S | L | L | R | E | C | R | A | N | G | G | K | V | I | F | D | N | N | Y | R | P | R | L | W | A | S | K | E | E | T | Q | Q | V | Y | Q | Q | M | L | E | C | T | D | I | A | F | L | T | L | D | D | E | D | A | L |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
M | D | E | S | R | I | F | Y | F | S | G | F | T | L | T | V | D | V | N | . |
. |
. |
. |
H | V | L | Q | A | C | R | K | A | R | E | V | D | G | L | F | M | I | N | L | S | A | P | . |
. |
. |
. |
F | I | M | Q | F | F | S | A | Q | L | G | E | V | L | P | Y | T | D | I | I | V | A | N | R | H | E | A | K | E | F |
Template Known Secondary structure |   |
 |  | T |
| S |  |  |  |  |  | T | T |  |  |  |  |
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
|  | . | . | . | . |  |  |  |  |  | S |  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
158 | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
|
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
  |
  |   |
205 | . | |
|
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
 |
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | G | . |
. |
. |
. |
. |
Q | Q | P | V | E | D | V | I | A | R | T | H | N | A | . |
. |
. |
. |
. |
. |
G | V | K | E | V | V | V | K | R | G | A | D | S | C | L | V | S | I | A | G | E | G | L | V | D | V | P | A | V | K | L | P | K | E | K | V | I | D | T | T | A | A | G | D | S | F | S | A | G | Y | L | A | V |
Query Conservation |   |
  |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
Template Sequence |   |
A | N | M | M | K | W | D | T | D | C | V | E | E | I | A | R | R | A | V | S | E | V | P | Y | T | G | T | K | G | R | V | V | V | F | T | R | D | I | E | S | T | V | L | A | T | K | D | G | V | . |
E | T | V | P | V | P | Q | L | D | Q | D | K | V | I | D | M | N | G | A | G | D | A | F | M | G | G | F | L | S | A |
Template Known Secondary structure |   |
 |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
| S | S |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T |  |  | . |  |  |  |
|
|
|
|
|
| T | T | S |
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | T | G | G | S | A | E | D | A | A | K | R | G | H | L | T | A | S | T | V | I | Q | Y | R | G | A | I |
Query Conservation |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |
Template Sequence |   |
Y | A | V | G | K | D | L | R | R | C | C | E | T | G | H | Y | T | A | Q | E | V | I | Q | R | K | P | S | F |
Template Known Secondary structure |   |
 |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |