|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | S | K | K | I | A | V | I | G | E | C | M | I | E | L | S | E | . |
. |
. |
. |
. |
. |
. |
K | G | A | D | V | K | R | G | F | G | G | D | T | L | N | T | S | V | Y | I | A | R | Q | V | D | P | A | A | L | T | V | H | Y | V | T | A | L | G | T | D | S | F | S | Q | Q | M | L | D | A | W | H | G | E | N | V | D |
Query Conservation |   |
|   |   |   |
|
|   |
|
|   |   |   |
|
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   | . | . |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |
| . | . | . | . |
|   |   |   |   |   |
|   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
Template Sequence |   |
V | D | . |
. |
V | I | A | L | G | E | P | L | I | Q | F | N | S | F | N | P | G | P | L | R | F | V | N | Y | F | E | K | H | V | A | G | S | E | L | N | F | C | I | A | V | V | R | N | . |
. |
. |
. |
H | L | S | C | S | L | I | A | R | V | G | N | D | E | F | G | K | N | I | I | E | Y | S | R | A | Q | G | I | D |
Template Known Secondary structure |   |
|
| . | . |  |  |  |  |
|
|
|  |  |  |  |  |  | S | S | S | S |
| G | G | G |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | T |
|
|  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| B |
Template Predicted Secondary structure |   |
|  | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | |
|
. | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
|
|
. | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
  |
  |   |
74 | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | S | L | T | Q | R | M | E | N | R | L | P | G | L | Y | Y | I | E | T | D | . |
. |
S | T | G | E | R | T | F | Y | Y | W | R | N | E | A | A | A | K | F | W | L | E | S | E | Q | S | A | A | I | C | E | E | L | A | N | F | D | Y | L | Y | L | S | G | I | S | L | A | I | L | S | P | T | S | R | E | K | L | L | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
Template Sequence |   |
T | S | H | I | K | V | D | N | E | S | F | T | G | I | Y | F | I | Q | R | G | Y | P | I | P | M | K | S | E | L | V | Y | Y | R | K | . |
. |
. |
G | S | A | G | S | R | L | S | P | E | D | I | N | E | N | Y | V | R | N | S | R | L | V | H | S | T | G | I | T | L | A | I | S | . |
. |
. |
. |
. |
D | N | A | K | E |
Template Known Secondary structure |   |
| T | T |  |  |  |  | T | T | S |
|
|
|  |  |  |  |  |  | S | S | S | S | T | T |
|  |  |  |  |  |  |
| T | . | . | . | T |
| S | G | G | G |
|
| G | G | G |
|
|  |  |  |  |  | T | S | S |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | |
|
|
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
. | . | . | . | . |
  |
  |   |
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | R | E | C | R | A | N | G | G | K | V | I | F | D | N | N | Y | R | P | R | L | W | A | S | K | E | E | T | Q | Q | V | Y | Q | Q | M | L | E | C | T | D | . |
. |
I | A | F | L | T | L | D | D | E | D | A | L | W | G | Q | Q | P | V | E | D | V | I | A | R | T | H | N | A | G | V | K | E | V | V | V | K | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |
Template Sequence |   |
A | V | I | K | A | F | E | L | A | K | S | R | S | L | D | T | N | I | R | P | K | L | W | S | S | L | E | K | A | K | E | T | I | L | S | I | L | K | K | Y | D | I | E | V | L | I | T | D | P | D | D | T | K | I | L | L | D | V | T | D | P | D | E | A | Y | R | K | Y | K | E | L | G | V | K | V | L | L | Y | K | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| S | S |  |  |  |  |
|
|
|
| G | G | G | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | D | S | C | L | V | S | I | A | G | E | G | L | V | D | V | P | A | V | K | L | P | K | E | K | V | I | D | T | T | A | A | G | D | S | F | S | A | G | Y | L | A | V | R | L | T | G | G | S | A | E | D | A | A | K | R | G | H | L | T | A | S | T | V | I | Q | Y | R | G | A | I | I | P | R | E | A | M | P |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |
| . | . | . |   |   |   |   |   |
|
Template Sequence |   |
G | S | K | G | A | I | A | Y | K | D | N | V | . |
. |
. |
. |
K | A | F | K | D | A | Y | K | V | P | V | E | D | P | T | G | A | G | D | A | M | A | G | T | F | V | S | L | Y | L | Q | G | K | D | I | E | Y | S | L | A | H | G | I | A | A | S | T | L | V | I | T | V | R | G | . |
. |
. |
D | N | E | L | T | P |
Template Known Secondary structure |   |
G | G | G |
|  |  |  |  |  | T | T |  | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S | . | . | . | S | S | T | T |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|  | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
|
. | . | . | . | . | . |
  |