|   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | N | H | S | V | Q | V | A | I | A | G | A | G | P | V | G | L | M | M | A | N | Y | L | G | Q | M | G | I | D | V | L | V | V | E | K | L | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | L | I | D | Y | P | R | A | I | G | I | D | D | E | A | L | R | T | M | Q | S | V | G | L | V | D | D | V | L | P | H | T |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|
|   |
|
|   |
|   |
|
|
|
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |
|
|   |
|   |   |
|
|
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | K | R | H | Y | E | A | V | V | I | G | G | G | I | I | G | S | A | I | A | Y | Y | L | A | K | E | N | K | N | T | A | L | F | E | S | G | T | M | G | G | R | T | T | S | A | A | A | G | M | L | G | A | H | A | E | C | E | E | R | D | A | F | F | D | F | A | M | H | S | Q | R | L | Y | K | G | L | G | E | E | L |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | T | T | T | T |  |  |  |  |
|
|
| B |
|
| G | G | G |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | W | H | A | M | R | F | L | T | P | K | G | R | C | F | A | D | I | Q | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | T | D | E | F | G | W | P | R | R | N | A | F | I | Q | P | Q | V | D | A | V | M | L | E | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | A | L | S | G | V | D | I | R | Q | H | N | G | G | M | F | K | L | A | F | S | E | E | D | V | L | Q | L | R | Q | M | D | D | L | D | S | V | S | W | Y | S | K | E | E | V | L | E | K | E | P | Y | A | S | G | D | I | F | G | A | S | F | I | Q | D | D | V | H | V | E | P | Y | F | V | C | K | A | Y | V | K | A |
Template Known Secondary structure |   |
 |  |  |  |
|
|
|
|
|
| B |
|
|
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  | T | T | T | T | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
| T | T |
|
|  |  |  |  |  | T | T |
|
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
127 | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | S | R | F | P | N | V | R | C | L | F | S | R | E | L | E | A | F | S | Q | Q | D | D | E | V | T | L | H | L | K | T | A | E | G | Q | R | E | I | V | K | A | Q | W | L | V | A | C | D | G | G | A | S | F | V | R | R | T | L | N | V | P | F | E | G | K | T | A | P | N | Q | W | I | V | V | D | I | A | N | D | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | K | M | L | G | . |
A | E | I | F | E | H | T | P | V | L | H | V | E | R | D | G | E | A | L | F | I | K | T | P | S | G | . |
. |
. |
. |
D | V | W | A | N | H | V | V | V | A | S | G | V | W | S | G | M | F | F | K | Q | L | G | L | N | N | A | F | L | P | V | K | G | E | C | L | S | V | W | N | D | D | I | P |
Template Known Secondary structure |   |
 |  |  | T | T | . |
|  |  |  | T | T |
|
|
|
|  |  |  |
| S | S | S | S |  |  |  |  |  | T | T |  | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
| G | G | G | T |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | |
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
|
|
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
207 | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | T | P | H | I | Y | L | C | C | D | P | V | R | P | Y | V | S | A | A | L | P | H | A | V | R | R | F | E | F | M | V | M | P | G | E | T | E | E | Q | L | R | E | P | Q | N | M | R | K | L | L | S | K | V | L | P | N | P | D | N | V | E | L | I | R | Q | R | V | Y | T | H | N | A | R | L | A | Q | R | F | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |
|   |   |
|
Template Sequence |   |
L | T | K | T | L | Y | . |
. |
. |
. |
. |
. |
H | D | H | C | Y | I | V | P | R | K | S | G | R | L | V | V | G | A | T | M | K | P | G | D | W | S | E | T | P | D | L | G | G | L | E | S | V | M | K | K | A | K | T | M | L | P | A | I | Q | N | M | K | V | D | R | F | W | A | . |
. |
. |
. |
G | L | R | P | G | T |
Template Known Secondary structure |   |
|
| S |  |  |  | . | . | . | . | . | . |  | T | T |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
|
|
|  |  | T |
|
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | G | G | S |
|  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
300 | . | . | . | . | . |
  |
  |   |
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . | . | . | |
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | D | R | V | L | L | A | G | D | A | A | H | I | M | P | V | W | Q | G | Q | G | Y | N | S | . |
G | M | R | D | A | F | N | L | A | W | K | L | A | . |
L | V | I | Q | G | K | A | R | D | A | L | L | D | T | Y | Q | Q | E | R | R |
Query Conservation |   |
  |
|
|
|   |
|
|
|
|
|
|
|   |   |   |
|   |   |
|
|
|   |
|   | . |
|
|   |
|
|   |   |
|
|
|
|
|
| . |   |
|   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
Template Sequence |   |
K | D | G | K | P | Y | I | G | R | H | P | E | D | S | R | I | L | F | A | A | G | H | F | R | N | G | I | L | L | A | P | A | T | G | A | L | I | S | D | L | I | M | N | K | E | V | N | Q | D | W | L | H | A | F | R | I | D | R | K |
Template Known Secondary structure |   |
T | T | S |
|
|  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
| S | S |
| T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  | T |
| S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
  |