|   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
210 | . | . | . | . | . | . | . | . | . | 220 | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
E | E | V | A | E | L | V | E | Y | L | R | E | P | S | R | F | Q | K | L | G | G | K | I | P | K | G | V | L | M | V | G | P | P | G | T | G | K | T | L | L | A | K | A | I | A | G | E | A | . |
. |
. |
. |
. |
. |
. |
. |
K | V | P | F | F | T | I | S | G | S | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |   |
|   | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
E | D | F | T | R | I | F | L | P | I | Y | D | S | L | X | . |
. |
. |
. |
. |
S | S | Q | N | K | L | F | Y | I | T | N | A | D | D | S | T | K | F | Q | L | V | N | D | V | X | D | E | L | I | T | S | S | A | R | K | E | L | P | I | F | D | Y | I | H | I | D | A | L | E | L | X | D | A | L | Y | E | K | I | W | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | T |
|
|
|  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T | T | S | S |
|
|  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
554 | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . |
  |
  |   |
|
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |  |  |
|
|  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
F | V | E | M | F | V | G | V | G | A | S | R | V | R | D | M | F | E | Q | . |
. |
A | K | K | A | A | P | C | I | I | F | I | D | E | I | D | A | V | G | R | Q | R | G | A | G | L | G | G | G | H | D | E | R | E | Q | T | L | N | Q | M | L | V | E | M | D | G | F | E | G | N | E | G | I | I | V | I | A | A | T |
Query Conservation |   |
. |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   | . | . |
|   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |
|
|
|
|   |
|
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|   |
|   |   |   |   |   | . | . |   |   |   |   |   |
|   |
|
|   |
|
|
Template Sequence |   |
A | I | S | K | E | N | G | D | I | S | L | E | A | L | N | F | Y | I | T | N | V | P | K | A | K | K | R | K | T | L | I | L | I | Q | N | P | E | N | L | L | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | I | L | Q | Y | F | E | K | W | I | S | . |
. |
S | K | N | S | K | L | S | I | I | C | V | G |
Template Known Secondary structure |   |
 |  | S |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | S |
| G | G | G | S |
|  |  |  |  |  |  |  |
|
| S | S | S |
|
| T | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . | . |
| S | S |
|
|  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
631 | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 680 | . | . | . | |
|
. | . | . | . | . | . | 690 | . | . | . | . | . |
  |
  |   |
298 | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
|
|
. | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|  | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | R | P | D | V | L | D | P | A | L | L | R | P | G | R | F | D | R | . |
. |
. |
Q | V | V | V | G | L | P | D | V | R | G | R | E | Q | I | L | K | V | H | M | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | V | P | L | A | P | D | I | D |
Query Conservation |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   | . | . | . |   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . |
Template Sequence |   |
G | H | N | V | T | I | R | E | Q | I | N | I | X | P | S | L | K | A | H | F | T | E | I | K | L | N | K | V | D | K | N | E | L | Q | Q | X | I | I | T | R | L | K | S | L | L | K | P | F | H | V | K | V | N | D | K | K | E | X | T | I | Y | N | N | I | P | D | N | V | I | V | I | N | H | K | I | N | N | K | I | . |
Template Known Secondary structure |   |
| S | S |
|
|
|  |  |  |  |  | T |
|  |  |  |  | T | T |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
| T | T |
|
|  |  |  |
|
|
|
|
| T | T |  |  |  |  |
|  |  |
|
|  |  |  | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
698 | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | |
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | |
|
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | I | I | A | R | G | T | P | G | F | S | G | A | . |
. |
D | L | A | N | L | V | N | E | A | A | L | F | A | A | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | N | K | R | V | V | S | M | V | E | F | E | K | A | K | D | K | I | M |
Query Conservation |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
| . | . |
|
|   |   |
|   |   |   |
|
|   |   |
|   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |
|   |   |
|
|   |   |   |
|
|
|
|   |
|
|   |
|
|
|   |
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
T | Q | L | I | A | K | N | V | A | N | V | S | G | S | T | E | K | A | F | K | I | C | E | A | A | V | E | I | S | K | K | D | F | V | R | K | G | G | L | Q | K | G | K | L | V | V | S | Q | E | X | V | P | R | Y | F | S | E | A | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  | T | T |  |  |
|
| S |  |  |
|
| T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
785 | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . |
  |