|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 30 | . | . | |
. | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | 50 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
M | T | M | P | T | N | Q | C | P | W | R | M | Q | V | H | H | I | T | Q | E | T | P | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | W | T | I | S | L | I | C | H | . |
D | Y | Y | P | Y | R | A | G | Q | Y | A | L | V | S | V | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | S | A | E | T |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |   |   | . |   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | N | L | F | K | K | S | N | P | Y | K | A | K | V | I | S | N | V | L | L | T | P | E | T | G | T | G | K | R | P | K | K | E | G | E | A | L | V | H | R | I | V | L | A | I | D | H | S | A | Y | P | Y | V | I | G | Q | S | G | G | V | I | P | P | G | E | D | P | E | K | K | A | K | G | L | A | D | V | G | Y | T |
Template Known Secondary structure |   |
|
| S | B | B | T | T | B |
|  |  |  |  |  |  |  |  |  |  |
| S |
|
| T | T | S | S | S | S |
| T | T | S |
|
|
|
|  |  |  |  |  |  |  |
|
| T | T | T |
|
|
|
| T | T |
|  |  |  |  |  |
| S | S | B |
|  |  |  |  |  |  | T |
| S |
|
| B |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
54 | . | . | . | . | . | 60 | . | . | . | |
|
|
. | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
. | . | . | 110 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | A | Y | T | I | S | S | T | P | . |
. |
. |
G | V | S | E | Y | I | T | L | T | V | R | R | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | G | V | G | S | Q | W | L | T | R | D | V | K | R | G | D | Y | L | W | L | S | D | A | M | G | E | F | T | C | . |
. |
D | D | K | A | E | D | K | F | L | L | L | A |
Query Conservation |   |
  |
|   |
|
|
|
|
|   |
| . | . | . |   |   |   |   |   |   |   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   | . |
|   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
Template Sequence |   |
V | R | L | Y | S | I | A | S | P | S | Y | F | G | M | K | E | D | N | I | E | F | I | I | K | R | D | N | I | Y | D | E | N | G | N | I | Q | F | K | G | V | C | S | N | Y | M | C | D | . |
L | K | P | G | D | E | V | T | M | T | G | P | S | G | K | K | F | L | L | P | N | T | D | F | S | G | D | I | M | F | L | A |
Template Known Secondary structure |   |
|  |  |  |  | B |
| S |
|
|
|
|
|
| S | S |
|  |  |  |  |  |  |  |
|
| B |
|
| B | T | T | T | B |
| S |
| B |
|  |  |  |  |  |  |  | T | . |
|
| T | T |
|  |  |  |  |  |  |  |  |
| S | S | S |
|
|
| S | S |
| B |
| S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | C | G | V | T | P | I | M | S | M | R | R | W | L | A | K | N | R | P | Q | . |
. |
. |
A | D | V | R | V | I | Y | N | V | R | T | P | Q | D | V | I | F | A | D | E | W | R | N | Y | P | V | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | A | E | N | N | V | T | E | G | F | I | A | G | R | L | T | R | E | L |
Query Conservation |   |
|
|   |
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
Template Sequence |   |
T | G | T | G | I | A | P | F | I | G | M | S | E | E | L | L | E | H | K | L | I | K | F | T | G | N | I | T | L | V | Y | G | A | P | Y | S | D | E | L | V | M | M | D | Y | L | K | G | L | E | S | K | H | K | N | F | K | L | I | T | A | I | S | R | E | E | K | N | S | F | D | G | G | R | M | Y | I | S | H | R | V |
Template Known Secondary structure |   |
 | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
| B |
| S |
|  |  |  |  |  |  |  | S | S | G | G | G |
|
| S |  |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  | T | T | T |
| B |
| T | T | T | S | S | B |
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
187 | . | . | 190 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | |
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | G | V | P | D | L | . |
. |
. |
. |
. |
A | S | R | T | V | M | T | C | G | P | A | P | . |
Y | M | D | W | V | E | Q | E | V | K | A | L | G | V | T | R | F | F | K | E | K | F | F | T | P | V | A | E | A | A | T | S | G | L | K | F |
Query Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |
|
|
|
|
|
|   |   | . |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
Template Sequence |   |
R | E | Q | A | E | A | V | K | K | I | L | N | G | G | G | R | F | Y | I | C | G | G | P | K | G | M | E | K | G | V | I | E | E | I | Q | K | I | S | G | N | T | G | T | Y | E | E | F | K | H | H | L | E | G | A | H | Q | L | F | V | E | T |
Template Known Secondary structure |   |
 |  | T |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | S | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| S |
|  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |