|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | |
. | 70 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
M | T | M | P | T | N | Q | C | P | W | R | M | Q | V | H | H | I | T | Q | E | T | P | . |
. |
. |
. |
. |
D | V | W | T | I | S | L | I | C | H | D | Y | Y | P | Y | R | A | G | Q | Y | A | L | V | S | V | R | N | S | A | E | T | L | R | A | Y | T | I | S | S | T | P | G | V | S | E | Y | . |
I | T | L | T | V | R |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . | . | . | . |
|
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   | . |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
I | N | L | Y | T | V | K | N | P | L | K | C | K | I | V | D | K | I | N | L | V | R | P | N | S | P | N | E | V | Y | H | L | E | I | N | H | N | G | L | F | K | Y | L | E | G | H | T | C | G | I | I | P | Y | Y | N | E | R | C | A | R | L | Y | S | I | S | S | S | N | N | M | E | N | L | S | V | A | I | K | I | H |
Template Known Secondary structure |   |
T | T | S | B |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |
| S |
| T | T |
| S | S |
|  |  |  |  |  |  |  |
| T | T |
|
|
|
|
| T | T |
|  |  |  |  |
| T | T |
|
|
|
|
| S |  |  |  |  | B |
| S |
| T | T | S | S | S |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
  |
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | |
|
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
R | I | D | D | G | V | G | S | Q | W | L | T | R | D | V | K | R | G | D | Y | L | W | L | S | D | A | M | G | E | F | T | C | D | D | . |
. |
. |
K | A | E | D | K | F | L | L | L | A | A | G | C | G | V | T | P | I | M | S | M | R | R | W | L | A | K | N | R | P | Q | A | D | . |
. |
. |
. |
. |
. |
. |
V | R | V |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |
|   |
|   |   |   |   | . | . | . |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|   |   | . |
|   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
K | Y | N | Y | G | Y | C | S | G | F | I | K | N | . |
L | K | I | N | D | D | I | Y | L | T | G | A | H | G | Y | F | N | L | P | N | D | A | I | Q | K | N | T | N | F | I | F | I | A | T | G | T | G | I | S | P | Y | I | S | F | L | K | K | L | F | A | Y | D | L | Y | N | R | N | S | N | Y | T | G | Y | I | T | I |
Template Known Secondary structure |   |
B |
|
| B |
|  |  |  |  |  |  |  |  | . |
|
| T | T |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| S | S |  |  |  |  | T |
|
|  |  |  |  |  |  | G | G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | |
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
  |
  |   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Y | N | V | R | T | P | Q | D | V | I | F | A | D | E | W | R | N | Y | P | V | T | . |
. |
. |
. |
. |
. |
. |
. |
L | V | A | E | N | N | V | T | E | G | F | I | A | G | R | L | . |
. |
. |
. |
. |
. |
T | R | E | L | L | A | G | V | P | D | L | A | S | R | T | V | M | T | C | G | P | A | P | Y | M | D | W | V |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
| . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   |   |
|
Template Sequence |   |
Y | Y | G | V | Y | N | E | D | S | I | L | Y | L | N | E | L | E | Y | F | Q | K | M | Y | P | N | N | I | N | I | H | Y | V | F | S | Y | K | Q | N | S | D | A | T | S | F | Y | V | Q | D | E | I | Y | K | R | K | T | E | F | L | N | L | F | N | N | Y | K | C | E | L | Y | I | C | G | H | K | S | I | R | Y | K | V |
Template Known Secondary structure |   |
 |  |  |  | S | S | G | G | G |
| T | T |  |  |  |  |  |  |  |  |  |  | S | T | T | T |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |
  |   |
211 | . | . | . | . | . | . | . | . | 220 | |
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | E | V | K | A | L | G | V | T | . |
. |
. |
R | F | F | K | E | K | F |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   | . | . | . |   |
|   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
Template Sequence |   |
M | D | I | L | K | Q | F | D | E | K | K | K | K | R | V | H | V | E | V | Y |
Template Known Secondary structure |   |
 |  |  |  |
|
|
|
| S | S | S | G | G | G |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
294 | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . |
  |