|   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
|
|
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
W | R | M | Q | V | H | H | I | T | Q | E | T | P | D | V | W | T | I | S | L | I | C | H | D | Y | . |
. |
. |
Y | P | Y | R | A | G | Q | Y | A | L | V | S | V | R | N | S | A | E | . |
T | L | R | A | Y | T | I | S | S | T | P | G | V | S | E | Y | I | T | L | T | V | R | . |
. |
. |
. |
. |
. |
. |
. |
R | I | D |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |
|   |
|
|   |   |
|   |
|   |   |   |   |   | . | . | . |   |   |
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   | . |   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|   |
|
| . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | H | C | R | L | V | A | K | K | E | L | S | R | D | V | R | L | F | R | F | S | L | P | S | P | D | Q | V | L | G | L | P | I | G | K | H | I | F | V | C | A | T | I | E | G | K | L | C | M | R | A | Y | T | P | T | S | M | V | D | E | I | G | H | F | D | L | L | V | K | V | Y | F | K | N | E | H | P | K | F | P |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
| B | T | T |  |  |  |  |  |  |  |
| S | S | T | T | S |
|
|
|
|
| T | T |
|
| B |
|
| B |
|
| B | T | T | B |
|
|
|
|
| B |
|
|
| S |
| T | T |
|
| S |  |  |  |  |  |  |  |
|
|
| S | S | S |
| T | T | S | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
D | G | V | G | S | Q | W | L | T | R | D | V | K | R | G | D | Y | L | W | L | S | D | A | M | G | E | F | T | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | K | A | E | D | K | F | L | L | L | A | A | G | C | G | V | T | P | I | M | S | M | R | R | W | L | A | K | N | R | P | Q | A | . |
. |
D | V | R | V | I |
Query Conservation |   |
  |
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |
|   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
N | G | G | L | M | T | Q | Y | L | D | S | L | P | V | G | S | Y | I | D | V | K | G | P | L | G | H | V | E | Y | T | G | R | G | S | F | V | I | N | G | K | Q | R | N | A | R | R | L | A | M | I | C | G | G | S | G | I | T | P | M | Y | Q | I | I | Q | A | V | L | R | D | Q | P | E | D | H | T | E | M | H | L | V |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  | S |
| T | T |
|
|
| B |
|
|
|
|
|
| S |
|  |  |
| S | S | S |  |  |  |
| S | S | S |  |  |  |
| S |  |  |  |  |
|
|
| S | S |
| S |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T |
|
|
|  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
. | 210 |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
Y | N | V | R | T | P | Q | D | V | I | F | A | D | E | W | R | N | Y | P | V | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | E | N | N | V | T | E | G | F | I | A | G | R | L | T | R | E | L | L | A | G | V | . |
. |
P | D | L | A | S | R | T | V | M | T | C | G | P | A | P | Y | M | D | . |
W | V |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|   |   | . |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |
Template Sequence |   |
Y | A | N | R | T | E | D | D | I | L | L | R | D | E | L | D | R | W | A | A | E | Y | P | D | R | L | K | V | W | Y | V | I | D | Q | V | K | R | P | E | E | G | W | K | Y | S | V | G | F | V | T | E | A | V | L | R | E | H | V | P | E | G | G | D | D | T | L | A | L | A | S | G | P | P | P | M | I | Q | F | A | I |
Template Known Secondary structure |   |
 |  |
| S | B | T | T |
|
| T | T | S |  |  |  |  | T |  |  |  |  | S | T | T | T |  |  |
|
|  |  |
| S | B |
| S |
| T | T | T |
|
|
| S | B |
| S | S |
|
|  |  |  |  |  | T | T | S |
|
|
| T | T | T |
|  |  |
|
|
| S |
| T |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
211 | . | . | . | . | . | . | . | . | 220 | |
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
E | Q | E | V | K | A | L | G | V | T | . |
. |
R | F | F | K | E |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   | . | . |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |
Template Sequence |   |
S | P | N | L | E | K | M | K | Y | D | M | A | N | S | F | V | V |
Template Known Secondary structure |   |
S | S |  |  |  |  | T | T |
|
| S | T | T | T | B |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
  |