Job Description P69910 Confidence 99.97% Date Thu Jan 5 12:12:18 GMT 2012 Rank 26 Aligned Residues 311 % Identity 12% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		95	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.					.	.	.	.	.	.	170
Predicted Secondary structure																																																																							.	.	.	.
Query SS confidence																																																																							.	.	.	.
Query Sequence		A	I	D	L	R	C	V	N	M	V	A	D	L	W	H	A	P	A	P	K	N	G	Q	A	V	G	T	N	T	I	G	S	S	E	A	C	M	L	G	G	M	A	M	K	W	R	W	R	K	R	M	E	A	A	G	K	P	T	D	K	P	N	L	V	C	G	P	V	Q	.	.	.	.	I	C	W	H	K	F	A
Query Conservation																																																																							.	.	.	.
Alig confidence																						.	.	.	.	.																						.	.	.	.	.	.	.	.	.															.	.	.	.
Template Conservation																						.	.	.	.	.																						.	.	.	.	.	.	.	.	.
Template Sequence		T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	.	.	.	.	.	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	.	.	.	.	.	.	.	.	.	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L
Template Known Secondary structure		G	T	T					G	G	G					T			G	G	G	.	.	.	.	.					S																	.	.	.	.	.	.	.	.	.		S	S	S							T	T
Template Predicted Secondary structure																						.	.	.	.	.																						.	.	.	.	.	.	.	.	.
Template SS confidence
		111	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130						.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.										.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.
		171	.	.	.	.	.						.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.				.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.
Predicted Secondary structure								.	.	.	.	.																							.	.	.
Query SS confidence								.	.	.	.	.																							.	.	.
Query Sequence		R	Y	W	D	V	E	.	.	.	.	.	L	R	E	I	P	M	R	P	G	Q	L	F	M	D	P	K	R	M	I	E	A	C	.	.	.	D	E	N	T	I	G	V	V	P	T	F	G	V	T	Y	T	G	N	Y	E	F	P	Q	P	L	H	D	A	L	D	K	F	Q	A	D	T	G	I	D	I	D	M	H	I
Query Conservation								.	.	.	.	.																							.	.	.
Alig confidence								.	.	.	.	.										.													.	.	.																																		.	.	.	.	.	.
Template Conservation																						.																																																	.	.	.	.	.	.
Template Sequence		Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	.	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	.	.	.	.	.	.	C	Y	V	G	F
Template Known Secondary structure				T	T														T	T		.	S	S														G	G	G								S	B		T	T	T		B	B													T	T	.	.	.	.	.	.
Template Predicted Secondary structure																						.																																																	.	.	.	.	.	.
Template SS confidence
		177	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.		.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.							.	.	.	.	.
		243	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.		280	.	.	.	.	.	.	.	.	.	290	.	.															.	.	.	.	.	.	.	300	.	.	.	.	.	.	.
Predicted Secondary structure																																							.														.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																							.														.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	A	A	S	G	G	F	L	A	P	F	V	A	P	D	I	V	W	D	F	R	L	P	R	V	K	S	I	S	A	S	G	H	K	F	G	L	.	A	P	L	G	C	G	W	V	I	W	R	D	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	A	L	P	Q	E	L	V	F	N	V	D	Y	L	G
Query Conservation																																							.														.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.	.																				.														.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation													.	.	.	.	.	.	.
Template Sequence		D	L	A	H	A	V	G	N	V	E	L	.	.	.	.	.	.	.	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L
Template Known Secondary structure				T	T	T	T	T	T	S			.	.	.	.	.	.	.						T								S	S	S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B
Template Predicted Secondary structure													.	.	.	.	.	.	.
Template SS confidence
		250	.	.	.	.	.	.	.	.	.	260								.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.
		308	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.		.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
Predicted Secondary structure																																																				.
Query SS confidence																																																				.
Query Sequence		G	Q	I	G	T	F	A	I	N	F	S	R	P	A	G	Q	V	I	A	Q	Y	Y	E	F	L	R	L	G	R	E	G	Y	T	K	V	Q	N	A	S	Y	Q	V	A	A	Y	L	A	D	E	I	.	A	K	L	G	P	Y	E	F	I	C	T	G	R	P	D	E	G	I	P	A	V	C	F	K	L	K	D	G	E
Query Conservation																																																				.
Alig confidence																																																				.
Template Conservation
Template Sequence		I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N
Template Known Secondary structure			S	S	G	G	G	G			S																																																			S		S	S	G	G	G	B		S									T	T
Template Predicted Secondary structure
Template SS confidence
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.
		387	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.		.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
Predicted Secondary structure																																											.
Query SS confidence																																											.
Query Sequence		D	P	G	Y	T	L	Y	D	L	S	E	R	L	R	L	R	G	W	Q	V	P	A	F	T	L	G	G	E	A	T	D	I	V	V	M	R	I	M	C	R	R	.	G	F	E	M	D	F	A	E	L	L	L	E	D	Y	K	A	S	L	K
Query Conservation																																											.
Alig confidence				.	.	.	.	.	.														.	.	.	.	.	.	.														.
Template Conservation				.	.	.	.	.	.														.	.	.	.	.	.	.
Template Sequence		K	D	.	.	.	.	.	.	V	F	Q	E	L	E	K	R	G	V	V	C	D	.	.	.	.	.	.	.	K	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I	L	D
Template Known Secondary structure				.	.	.	.	.	.							T	T	T					.	.	.	.	.	.	.			T	T	T					B			T	T	T																		T
Template Predicted Secondary structure				.	.	.	.	.	.														.	.	.	.	.	.	.
Template SS confidence
		412	.							.	.	.	.	.	.	420	.	.	.	.	.	.								.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions