Job Description P69910 Confidence 100.00% Date Thu Jan 5 12:12:18 GMT 2012 Rank 6 Aligned Residues 425 % Identity 16% Template c2okkA_ PDB info PDB header:lyase Chain: A: PDB Molecule:glutamate decarboxylase 2; PDBTitle: the x-ray crystal structure of the 65kda isoform of glutamic acid2 decarboxylase (gad65) Resolution 2.30 Å

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		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20			.	.	.	.	.	.	.	.	.								30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.		.	.	.	60	.	.	.	.	.	.	.	.	.	70	.
Predicted Secondary structure																			.	.										.	.	.	.	.	.	.																												.																.	.
Query SS confidence																			.	.										.	.	.	.	.	.	.																												.																.	.
Query Sequence		K	Q	V	T	D	L	R	S	E	L	L	D	S	R	F	G	A	.	.	K	S	I	S	T	I	A	E	S	.	.	.	.	.	.	.	K	R	F	P	L	H	E	M	R	D	D	V	A	F	Q	I	I	N	D	E	L	Y	L	D	G	N	A	.	R	Q	N	L	A	T	F	C	Q	T	W	D	D	E	N	.	.
Query Conservation																			.	.										.	.	.	.	.	.	.																												.																.	.
Alig confidence																			.	.										.	.	.	.	.	.	.																												.																.	.
Template Conservation
Template Sequence		Q	D	V	M	N	I	L	L	Q	Y	V	V	K	S	F	D	R	S	T	K	V	I	D	F	H	Y	P	N	E	L	L	Q	E	Y	N	W	E	L	A	D	Q	P	Q	N	L	E	E	I	L	M	H	C	Q	T	T	L	K	Y	A	I	K	T	G	H	P	R	Y	F	N	Q	L	S	T	G	L	D	M	V	G	L
Template Known Secondary structure																		T	T	S		S													S						S	S																		S			T	T	S	T	T			S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		112	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.
		72	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	K	L	M	D	L	S	I	N	K	N	W	I	D	K	E	E	Y	P	Q	S	A	A	I	D	L	R	C	V	N	M	V	A	D	L	W	H	A	P	A	P	K	N	G	Q	A	V	G	T	N	T	I	G	S	S	E	A	C	M	L	G	G	M	A	M	K	W	R	W	R	K	R	M	E	A	A	G	K	P
Query Conservation
Alig confidence																																												.	.	.
Template Conservation																																												.	.	.
Template Sequence		A	A	D	W	L	T	S	T	A	N	T	N	M	F	T	Y	E	I	A	P	V	F	V	L	L	E	Y	V	T	L	K	K	M	R	E	I	I	G	W	P	G	G	.	.	.	S	G	D	G	I	F	S	P	G	G	A	I	S	N	M	Y	A	M	M	I	A	R	F	K	M	F	P	E	V	K	E	K	G	M	A
Template Known Secondary structure														S	S		T	T	T																				T		G	G	G	.	.	.		S						S	S																		T	T						G	G
Template Predicted Secondary structure																																												.	.	.
Template SS confidence
		192	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.				.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.
				152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.				.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.							.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
Predicted Secondary structure		.	.																									.	.	.																												.	.	.	.	.	.
Query SS confidence		.	.																									.	.	.																												.	.	.	.	.	.
Query Sequence		.	.	T	D	K	P	N	L	V	C	G	P	V	Q	I	C	W	H	K	F	A	R	Y	W	D	V	.	.	.	E	L	R	E	I	P	M	R	P	G	Q	L	F	M	D	P	K	R	M	I	E	A	C	D	E	N	T	.	.	.	.	.	.	I	G	V	V	P	T	F	G	V	T	Y	T	G	N	Y	E	F	P
Query Conservation		.	.																									.	.	.																												.	.	.	.	.	.
Alig confidence		.	.																									.	.	.											.																	.	.	.	.	.	.
Template Conservation																																									.
Template Sequence		A	L	P	R	L	I	A	F	T	S	E	H	S	H	F	S	L	K	K	G	A	A	A	L	G	I	G	T	D	S	V	I	L	I	K	C	D	E	R	.	G	K	M	I	P	S	D	L	E	R	R	I	L	E	A	K	Q	K	G	F	V	P	F	L	V	S	A	T	A	G	T	T	V	Y	G	A	F	D	P	L
Template Known Secondary structure		G	S									T	T	S		T									T	T	S		G	G	G						B		T	T	.	S		B															T	T										B	S		T	T	T			B
Template Predicted Secondary structure																																									.
Template SS confidence
		269	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.		.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	P	L	H	D	A	L	D	K	F	Q	A	D	T	G	I	D	I	D	M	H	I	D	A	A	S	G	G	F	L	A	P	F	V	A	P	D	I	V	W	D	F	R	L	P	R	V	K	S	I	S	A	S	G	H	K	F	G	L	A	P	L	G	C	G	W	V	I	W	R	D	E	E	A	L	P	Q	E	L	V
Query Conservation
Alig confidence													.	.	.	.	.	.																									.																	.
Template Conservation													.	.	.	.	.	.																									.																	.
Template Sequence		L	A	V	A	D	I	C	K	K	Y	K	.	.	.	.	.	.	I	W	M	H	V	D	A	A	W	G	G	G	L	L	M	S	R	K	H	K	W	K	L	S	.	G	V	E	R	A	N	S	V	T	W	N	P	H	M	M	G	.	V	P	L	Q	C	S	A	L	L	V	R	E	E	G	L	M	Q	N	C	N	Q
Template Known Secondary structure												T	.	.	.	.	.	.								T	T	G	G	G	G	G	G		T	T	T	G	G	G	G	T	.	T	G	G	G		S											.		S	S								S	S	T	T
Template Predicted Secondary structure													.	.	.	.	.	.																									.																	.
Template SS confidence
		348	.	350	.	.	.	.	.	.	.	.							.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.		.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.		.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
		301	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380
Predicted Secondary structure
Query SS confidence
Query Sequence		F	N	V	D	Y	L	G	G	Q	I	G	T	F	A	I	N	F	S	R	P	A	G	Q	V	I	A	Q	Y	Y	E	F	L	R	L	G	R	E	G	Y	T	K	V	Q	N	A	S	Y	Q	V	A	A	Y	L	A	D	E	I	A	K	L	G	P	Y	E	F	I	C	T	G	R	P	D	E	G	I	P	A	V	C	F
Query Conservation
Alig confidence								.	.													.																																																	.	.
Template Conservation								.	.													.																																																	.	.
Template Sequence		M	H	D	L	S	Y	.	.	D	T	G	D	K	A	L	Q	C	G	R	H	.	V	D	V	F	K	L	W	L	M	W	R	A	K	G	T	T	G	F	E	A	H	V	D	K	C	L	E	L	A	E	Y	L	Y	N	I	I	K	N	R	E	G	Y	E	M	V	F	D	G	.	.	K	P	Q	H	T	N	V	C	F
Template Known Secondary structure					G	G	G	.	.			G	G	G	S	S		S	S			.																																						T	S	T	T				S	S	S	S	.	.			S	S	S
Template Predicted Secondary structure								.	.													.																																																	.	.
Template SS confidence
		421	.	.	.	.	.			.	.	.	430	.	.	.	.	.	.	.	.		.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.			.	.	.	490	.	.	.	.	.
		381	.	.	.	.	.	.	.	.	390	.										.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.		.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.
Predicted Secondary structure													.	.	.	.	.	.	.	.	.																																			.
Query SS confidence													.	.	.	.	.	.	.	.	.																																			.
Query Sequence		K	L	K	D	G	E	D	P	G	Y	T	.	.	.	.	.	.	.	.	.	L	Y	D	L	S	E	R	L	R	L	R	G	W	Q	V	P	A	F	T	L	G	G	E	A	T	D	I	V	V	M	R	I	M	C	.	R	R	G	F	E	M	D	F	A	E	L	L	L	E	D	Y	K	A	S	L	K	Y
Query Conservation													.	.	.	.	.	.	.	.	.																																			.
Alig confidence													.	.	.	.	.	.	.	.	.																			.	.															.
Template Conservation																																								.	.
Template Sequence		W	Y	I	P	P	S	L	R	T	L	E	E	R	M	S	R	L	S	K	V	A	P	V	I	K	A	R	M	M	E	Y	G	T	T	M	V	S	Y	.	.	Q	P	L	G	D	K	V	N	F	F	R	M	V	I	S	N	P	A	A	T	H	Q	D	I	D	F	L	I	E	E	I	E	R	L	G	Q	D
Template Known Secondary structure						T	T	T	T	T									T	T													T	S						.	.				T	T												T	T
Template Predicted Secondary structure																																								.	.
Template SS confidence
		507	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.			.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.