Job Description P0AES4 Confidence 100.00% Date Thu Jan 5 11:24:06 GMT 2012 Rank 10 Aligned Residues 440 % Identity 47% Template c2novD_ PDB info PDB header:isomerase Chain: D: PDB Molecule:dna topoisomerase 4 subunit a; PDBTitle: breakage-reunion domain of s.pneumoniae topo iv: crystal2 structure of a gram-positive quinolone target Resolution 2.67 Å

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		33	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	P	D	V	R	D	G	L	K	P	V	H	R	R	V	L	Y	A	M	N	V	L	G	N	D	W	N	K	A	Y	K	K	S	A	R	V	V	G	D	V	I	G	K	Y	H	P	H	G	D	S	A	V	Y	D	T	I	V	R	M	A	Q	P	F	S	L	R	Y	M	L	V	D	G	Q	G	N	F	G	S	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	L	P	D	I	R	D	G	L	K	P	V	Q	R	R	I	L	Y	S	M	N	K	D	S	N	T	F	D	K	S	Y	R	K	S	A	K	S	V	G	N	I	M	G	N	F	H	P	H	G	D	S	S	I	Y	D	A	M	V	R	M	S	Q	N	W	K	N	R	E	I	L	V	E	M	H	G	N	N	G	S	M
Template Known Secondary structure					B	T	T	T				T	T	T	T	T	T							T	T			S	S	S														T	T	T			S		S										S	S		T	T	T		S	S		S					S
Template Predicted Secondary structure
Template SS confidence
		29	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
		113	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	G	D	S	A	A	A	M	R	Y	T	E	I	R	L	A	K	I	A	H	E	L	M	A	D	L	E	K	E	T	V	D	F	V	D	N	Y	D	G	T	E	K	I	P	D	V	M	P	T	K	I	P	N	L	L	V	N	G	S	S	G	I	A	V	G	M	A	T	N	I	P	P	H	N	L	T	E	V	I	N
Query Conservation
Alig confidence		.																																																														.	.	.	.
Template Conservation		.																																																														.	.	.	.
Template Sequence		.	D	D	P	P	A	A	M	R	Y	T	E	A	R	L	S	E	I	A	G	Y	L	L	Q	D	I	E	K	K	T	V	P	F	A	W	N	F	D	D	T	E	K	E	P	T	V	L	P	A	A	F	P	N	L	L	V	N	G	S	T	G	I	.	.	.	.	A	T	D	I	P	P	H	N	L	A	E	V	I	D
Template Known Secondary structure		.							T	T	T														S	S	T	T	T	T		S						S	S	S	S	S				S	S				S	S						T		B				.	.	.	.			B	B
Template Predicted Secondary structure		.																																																														.	.	.	.
Template SS confidence
			109	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.					170	.	.	.	.	.	.	.	.	.	180	.	.	.
		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	C	L	A	Y	I	D	D	E	D	I	S	I	E	G	L	M	E	H	I	P	G	P	D	F	P	T	A	A	I	I	N	G	R	R	G	I	E	E	A	Y	R	T	G	R	G	K	V	Y	I	R	A	R	A	E	V	E	V	D	A	K	T	G	R	E	T	I	I	V	H	E	I	P	Y	Q	V	N	K	A	R
Query Conservation
Alig confidence																																																											.	.
Template Conservation																																																											.	.
Template Sequence		A	A	V	Y	M	I	D	H	P	T	A	K	I	D	K	L	M	E	F	L	P	G	P	D	F	P	T	G	A	I	I	Q	G	R	D	E	I	K	K	A	Y	E	T	G	K	G	R	V	V	V	R	S	K	T	E	I	E	.	.	K	L	K	G	G	K	E	I	V	I	T	E	I	P	Y	E	I	N	K	A	N
Template Known Secondary structure										S	S							T	T	T			S				T	T							S									S	S									B					.	.			S	S	S							B			T	T
Template Predicted Secondary structure																																																											.	.
Template SS confidence
		189	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.			.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.
		273	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	I	E	K	I	A	E	L	V	K	E	K	R	V	E	G	I	S	A	L	R	D	E	S	D	K	D	G	M	R	I	V	I	E	V	K	R	D	A	V	G	E	V	V	L	N	N	L	Y	S	Q	T	Q	L	Q	V	S	F	G	I	N	M	V	A	L	H	H	G	Q	P	K	I	M	N	L	K	D	I	I	A
Query Conservation
Alig confidence															.	.	.																																	.	.	.
Template Conservation															.	.	.																																	.	.	.
Template Sequence		L	V	K	K	I	D	D	V	R	V	N	N	K	.	.	.	V	A	E	V	R	D	E	S	D	R	D	G	L	R	I	A	I	E	L	K	K	D	A	N	T	E	L	V	L	N	Y	L	.	.	.	T	D	L	Q	I	N	Y	N	F	N	M	V	A	I	D	N	F	T	P	R	Q	V	G	I	V	P	I	L	S
Template Known Secondary structure								T	T	T	T	T	T		.	.	.										S	S	S								S	S	S		S	S	T	T	G	G	G	T		.	.	.			S	S						B						T	T							S
Template Predicted Secondary structure															.	.	.																																	.	.	.
Template SS confidence
		268	.	270	.	.	.	.	.	.	.	.	.	280				.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.				.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.
		353	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	F	V	R	H	R	R	E	V	V	T	R	R	T	I	F	E	L	R	K	A	R	D	R	A	H	I	L	E	A	L	A	V	A	L	A	N	I	D	P	I	I	E	L	I	R	H	A	P	T	P	A	E	A	K	T	A	L	V	A	N	P	W	Q	L	G	N	V	A	A	M	L	E	R	A	G	D	D	A	A
Query Conservation
Alig confidence																																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		S	Y	I	A	H	R	R	E	V	I	L	A	R	S	R	F	D	K	E	K	A	E	K	R	L	H	I	V	E	G	L	I	R	V	I	S	I	L	D	E	V	I	A	L	I	R	A	S	E	N	K	A	D	A	K	E	N	L	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure																																						S										T	S	S	S					T	T				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		348	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.
		433	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	P	E	W	L	E	P	E	F	G	V	R	D	G	L	Y	Y	L	T	E	Q	Q	A	Q	A	I	L	D	L	R	L	Q	K	L	T	G	L	E	H	E	K	L	L	D	E	Y	K	E	L	L	D	Q	I	A	E	L	L	R	I	L	G	S	A	D	R	L	M	E	V	I	R	E	E	L	E	L	V	R	E	Q
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	D	F	T	E	E	Q	A	E	A	I	V	T	L	Q	L	Y	R	L	T	N	T	D	V	V	V	L	Q	E	E	E	A	E	L	R	E	K	I	A	M	L	A	A	I	I	G	D	E	R	T	M	Y	N	L	M	K	K	E	L	R	E	V	K	K	K
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.													S			G	G	G	G	S	S					T																						S	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																	407	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.
		513	.	.	.	.	.	.	520	.
Predicted Secondary structure
Query SS confidence
Query Sequence		F	G	D	K	R	R	T	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	A	T	P	R	L	S	S	L
Template Known Secondary structure		T						S	B
Template Predicted Secondary structure
Template SS confidence
		474	.	.	.	.	.	480	.	.