|   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | A | L | P | D | V | R | D | G | L | K | P | V | H | R | R | V | L | Y | A | M | N | V | L | G | N | D | W | N | K | A | Y | K | K | S | A | R | V | V | G | D | V | I | G | K | Y | H | P | H | G | D | S | A | V | Y | D | T | I | V | R | M | A | Q | P | F | S | L | R | Y | M | L | V | D | G | Q | G | N | F | G |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|
|
|
|   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
|   |
|
|   |
|   |
|   |
|
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |
|
|
|   |
|   |
|
|
|
|
Template Sequence |   |
D | R | A | L | P | F | I | G | D | G | L | K | P | V | Q | R | R | I | V | Y | A | M | S | E | L | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | T | V | G | D | V | L | G | K | Y | H | P | H | G | D | S | A | C | Y | E | A | M | V | L | M | A | Q | P | F | S | Y | R | Y | P | L | V | D | G | Q | G | N | W | G |
Template Known Secondary structure |   |
|
|
|
|
| B | T | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | S | T | T |
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  | T | T | T | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  | T | S | T | T | S |
| S | S |
| S |  |  |  |
| S |
|
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
28 | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
  |
  |   |
111 | . | . | . | . | |
. | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | I | D | G | D | . |
S | A | A | A | M | R | Y | T | E | I | R | L | A | K | I | A | H | E | L | M | A | D | L | E | K | E | T | V | D | F | V | D | N | Y | D | G | T | E | K | I | P | D | V | M | P | T | K | I | P | N | L | L | V | N | G | S | S | G | I | A | V | G | M | A | T | N | I | P | P | H | N | L | T | E |
Query Conservation |   |
|   |
|
|
| . |   |
|
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |   |
|
|
|   |   |
|
|
|
|   |   |   |
|
|   |
|
|
|   |   |
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|
|   |
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |   |   |
|
|   |   |
|
|   |   |   |
|   |
|
|
|
|
|   |   |
|
|
|
|
|   |
|
|   |
|
|
|
|
|   |   |
|
Template Sequence |   |
A | P | D | D | P | K | S | F | A | A | M | R | Y | T | E | S | R | L | S | K | Y | S | E | L | L | L | S | E | L | G | Q | G | T | A | D | W | V | P | N | F | D | G | T | L | Q | E | P | K | M | L | P | A | R | L | P | N | I | L | L | N | G | T | T | G | I | A | V | G | M | A | T | D | I | P | P | H | N | L | R | E |
Template Known Secondary structure |   |
S | S | S | S |
|
|
| T | T | S | S |
| G | G | G |  |  |  |
| G | G | G |  |  |  |  | T | T | T | T | S | S |
| S |
|  |  |  |
| T | T | S | S | S |  |  |  | S | S |
|
|
| S | S |
|  |  |  |  |  |
|
|
| S |
|
| S | S |
| S |
| B |
|
|
| B |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
108 | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . |
  |
  |   |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | N | G | C | L | A | Y | I | D | D | E | D | I | S | I | E | G | L | M | E | H | I | P | G | P | D | F | P | T | A | A | . |
I | I | N | G | R | R | G | I | E | E | A | Y | R | T | G | R | G | K | V | Y | I | R | A | R | A | E | V | E | V | D | A | K | T | G | R | E | T | I | I | V | H | E | I | P | Y | Q | V |
Query Conservation |   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
|
|
|
|
|
|
| . |   |
|   |   |   |   |
|
|   |   |   |
|   |
|
|   |
|   |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . |   |   |   |
|   |
|
|
|
|
|   |   |
|
Template Sequence |   |
V | A | Q | A | A | I | A | L | I | D | Q | P | K | T | T | L | D | Q | L | L | D | I | V | Q | G | P | D | Y | P | T | E | A | E | I | I | T | S | R | A | E | I | R | K | I | Y | E | N | G | R | G | S | V | R | M | R | A | V | W | K | K | E | . |
. |
. |
. |
. |
. |
D | G | A | V | V | I | S | A | L | P | H | Q | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  | T | T | T |
|
| S | B |
|
| S | S | S | S |  |  |
| S |
| T | T |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |
|  |  |  |  |  | . | . | . | . | . | . | T | T |  |  |  |  |  |  |
|
| T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
  |
  |   |
269 | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | |
. | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | |
. | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
N | K | A | R | L | I | E | K | I | A | E | L | V | K | E | K | R | V | E | G | I | S | A | L | R | D | E | S | D | K | D | G | . |
M | R | I | V | I | E | V | K | R | D | . |
A | V | G | E | V | V | L | N | N | L | Y | S | Q | T | Q | L | Q | V | S | F | G | I | N | M | V | A | L | . |
H | H | G | Q | P | K | I | M |
Query Conservation |   |
  |
|   |   |   |
|
|   |
|   |   |
|
|   |   |
|
|
|   |   |
|   |
|   |
|
|
|
|   |   |   |
| . |
|
|
|
|
|
|
|
|   |   | . |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |
| . |   |   |   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|   |   |   |
Template Sequence |   |
S | G | A | R | V | L | E | Q | I | A | A | Q | M | R | N | K | K | L | P | M | V | D | D | L | R | D | E | S | D | H | E | N | P | T | R | L | V | I | V | P | R | S | N | R | V | D | M | D | Q | V | M | N | H | L | F | A | T | T | D | L | E | K | S | Y | R | I | N | L | N | M | I | G | L | D | G | R | P | A | V | K |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T |  |  |  |  |  |  |
|
|
| S | S | S | T | T |
|  |  |  |  |  | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |  |  |  |  |
|  |  |  |
| T | T | S |
|  |  |  |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | K | D | I | I | A | A | F | V | R | H | R | R | E | V | V | T | R | R | T | I | F | E | L | R | K | A | R | D | R | A | H | I | L | E | A | L | A | V | A | L | A | N | I | D | P | I | I | E | L | I | R | H | A | P | T | P | A | E | A | K | T | A | L | V | A | N | P | W | Q | L | G | N | V | A | A | M | L | E |
Query Conservation |   |
  |
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|
|
|   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |
|   |   | . | . | . |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
N | L | L | E | I | L | S | E | W | L | V | F | R | R | D | T | V | R | R | R | L | N | Y | R | L | E | K | V | L | K | R | L | H | I | L | E | G | L | L | V | A | F | L | N | I | D | E | V | I | E | I | I | R | N | E | D | E | . |
. |
. |
P | K | P | A | L | M | S | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | S | S | S | . | . | . |  |  |  |  |  |  |  | S | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | |
|
|
. | 400 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
426 | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | G | D | D | A | A | R | P | E | W | L | E | P | E | F | G | V | R | D | G | L | Y | Y | L | T | E | Q | Q | A | Q | A | I | L | D | L | R | L | Q | K | L | T | G | L | E | H | E | K | L | L | D | E | Y | K | E | L | L | D | Q | I | A | E | L | L | R | I | L | G | S | A | D | R | L | M | E | V | I | R | E | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|
|   |   |
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | G | L | T | E | T | Q | A | E | A | I | L | E | L | K | L | R | H | L | A | K | L | E | E | M | K | I | R | G | E | Q | S | E | L | E | K | E | R | D | Q | L | Q | G | I | L | A | S | E | R | K | M | N | N | L | L | K | K | E |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
| T | T |  |  |  |  |  |  | T |
|
| G | G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
407 | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . |
  |
  |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | |
|
. | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
| . | . |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | L | V | R | E | Q | F | G | D | K | R | R | T | E | I | T | . |
. |
A | N | S | A | D | I | N | L | E | D | L | I | T | Q | E | D | V | V | V | T | L | S | H | Q | G | Y | V | K | Y | Q | P | L | S | E | Y | E | A | Q | R | R | G | G | K | G | K | S | A | A | R | I | K | E | E | D | F | I | D | R | L | L | V |
Query Conservation |   |
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |
|   | . | . |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |
|   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |
|   |
|   |
|
|   |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
L | Q | A | D | A | Q | A | Y | G | D | D | R | R | S | P | L | Q | E | R | E | E | A | K | A | M | S | E | H | D | M | L | P | S | E | P | V | T | I | V | L | S | Q | M | G | W | V | R | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | K | G | F | K | A | A | V | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
| S |
| B |
|
|
|
|
|
|
|
|
|
| S | S | T | T | S |
|
|
|
|
|
|  |  |  |  | T | T | T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
465 | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 520 | . |
  |
  |   |
584 | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | N | T | H | D | H | I | L | C | F | S | S | R | G | R | V | Y | S | M | K | V | Y | Q | L | P | E | A | T | R | G | A | R | G | R | P | I | V | N | L | L | P | L | E | Q | D | E | R | I | T | A | I | L | P | V | T | E | F | E | E | G | V | K | V | F | M | A | T | A | N | G | T | V | K | K | T | V | L | T | E | F |
Query Conservation |   |
  |   |
|   |
|   |
|
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|
|
|
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |
|
|   |
|
|
|   |
|
|
|
|   |
|
|   |   |   |
|
|   |   | . | . | . | . | . |
|   |   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   | . | . | . |   |   |   |
|
|   |   |
|
|   |
|   |
|
|
|   |   |
|   |   |
|
Template Sequence |   |
G | K | S | N | Q | P | V | V | F | V | D | S | T | G | R | S | Y | A | I | D | P | I | T | L | P | S | A | . |
. |
. |
. |
. |
R | E | P | L | T | G | K | L | T | L | P | P | G | A | T | V | D | H | M | L | M | E | S | D | . |
. |
. |
D | Q | K | L | L | M | A | S | D | A | G | Y | G | F | V | C | T | F | N | D | L |
Template Known Secondary structure |   |
|
| S | S | S |
|  |  |  |  |  | T | T | S |  |  |  |  |  |
| T | T | T | S |
|
|
| . | . | . | . | . |
|
| B | S | T | T | T | S |
|
|
| T | T |
|
|  |  |  |  |  |
|
|
| T | . | . | . | T |
|  |  |  |  |  | B | T | T | S |  |  |  |  |  |  | G | G | G | G |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
537 | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | |
|
|
. | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . |
  |
  |   |
664 | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | |
690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | |
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
N | R | L | R | T | A | G | K | V | A | I | K | L | V | D | G | D | E | L | I | G | V | D | L | T | S | . |
G | E | D | E | V | M | L | F | S | A | E | G | K | V | V | R | F | K | E | S | S | V | R | A | M | G | C | N | T | T | G | V | R | G | I | R | L | G | E | G | D | K | . |
. |
. |
. |
. |
. |
V | V | S | L | I |
Query Conservation |   |
  |   |   |
|   |   |
|   |   |
|
|   |
|   |
|   |
|
|
|
|   |
|   |   |   |   | . |   |   |   |   |
|
|
|   |
|   |   |
|   |   |
|
|
|   |   |   |
|
|
|   |   |
|
|   |
|   |
|
|
|
|
|   |
|   |   |   |
|   | . | . | . | . | . | . |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|   |   |
|   |   |
|
|
|   |   |   |
|
|
|   |   |
|
| . |
|
|
|
|
|
|
|
|
|   |   |   |
|   |
|
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
V | A | R | N | R | A | G | K | A | L | I | T | L | P | E | N | A | H | V | M | P | P | V | V | I | E | D | A | S | D | M | L | L | A | I | T | Q | A | G | R | M | L | M | F | P | V | S | D | L | P | Q | L | S | K | . |
G | K | G | N | K | I | I | N | I | P | S | A | E | A | A | R | G | E | D | G | L | A | Q | L | Y |
Template Known Secondary structure |   |
|
|
| S | T | T |
|  |  |
| B |
|
|
| T | T |
|
| B |
|
|
|  |  |
|
|
| T | T |
|  |  |  |  |  |  | T | T | S |  |  |  |  |  |  | S | T | T | S |
| B |
| S | S | . | B | S |
|  |  | S | S |
|
|
|  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
612 | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | |
. | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 |
  |
  |   |
737 | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | |
. | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | P | R | G | D | G | A | I | L | T | A | T | Q | N | G | Y | G | K | R | T | A | V | A | E | Y | P | T | K | S | . |
R | A | T | K | G | V | I | S | I | K | V | T | E | R | N | G | L | V | V |
Query Conservation |   |
|   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |
|
|
|
|   |   |   |
|
|
|   |   |   | . |
|
|
|
|
|
|   |   |   |
|   |   |   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
Template Sequence |   |
V | L | P | P | Q | S | T | L | T | I | H | V | G | K | R | K | I | K | L | R | P | E | E | L | Q | K | V | T | G | E | R | G | R | R | G | T | L | M | R | G | L | Q | R | I | D | R | V | E | I |
Template Known Secondary structure |   |
 |  |
| S | S |
|
|  |  |  |  |  | T | T |  |  |  |  |  |
|  |  |  |  | T | T | S | B |
|
| T | T | S |
|
|  |  |
| T | T |
|
| S |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
691 | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . |
  |