|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | |
. | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | I | G | Q | Y | Q | L | R | N | R | L | I | A | A | P | M | A | G | I | . |
. |
. |
. |
. |
. |
. |
T | D | R | P | F | R | T | L | C | Y | E | . |
M | G | A | G | L | T | V | S | E | M | M | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | N | P | Q | V | W | E | S | D | K | S | R | L | R |
Query Conservation |   |
|   |
|
|   |   |   |
|   |
|
|
|   |
|
|
|
|   |
|   | . | . | . | . | . | . | . |
|
|   |   |
|
|   |   |   |   |   | . |   |
|   |   |
|   |   |
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |
Template Sequence |   |
Y | K | M | G | R | F | N | L | S | H | R | V | V | L | A | P | L | T | R | Q | R | S | Y | G | N | V | P | Q | P | H | A | A | I | Y | Y | S | Q | R | T | T | P | G | G | F | L | I | T | E | A | T | G | V | S | D | T | A | Q | G | Y | Q | D | T | P | G | I | W | T | K | E | H | V | E | A | W | K | P | I | V | D | A |
Template Known Secondary structure |   |
 |  |  | T | T |  |  |  | S |
| S |  |  |  |
|
|
|
|
|
|
| S | G | G | G |
|
|
|  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |
| S |
|  |  | S | S | T | T |
|
|
| S | T | T |
|
| B |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
16 | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
  |
  |   |
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | V | H | I | D | E | P | G | I | R | T | V | Q | I | A | G | S | D | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | E | M | A | D | A | A | R | I | N | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   | . | . |
|   |   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |
|
|   |
Template Sequence |   |
V | H | A | K | . |
. |
G | G | I | F | F | C | Q | I | W | H | V | G | R | V | S | N | S | G | F | Q | P | N | G | K | A | P | I | S | C | S | D | K | P | L | M | P | Q | I | R | S | N | G | I | D | E | A | L | F | T | P | P | R | R | L | G | I | E | E | I | P | G | I | V | N | D | F | R | L | A | A | R | N | A | M |
Template Known Secondary structure |   |
 |  |  | T | . | . | T |
|  |  |  |  |  |  |  |
|
| T | T | S | S |
| G | G | G | S | G | G | G |
|
|
|  |  | S | S |
|
|
| S |
| T | T |
| B |
| S | S | S | S | S | B | S | S |
|
|
|  |  |
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
96 | . | . | . | |
|
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
88 | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
E | S | G | A | Q | I | I | D | I | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
M | G | C | P | A | K | K | V | N | R | K | L | A | G | S | A | L | L | Q | Y | P | D | V | V | K | S | I | L | T | E | V | V | N | A | V | D | V | P | V | T | L | K | I | R | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | W | A | P | E | H | R |
Query Conservation |   |
  |   |
|   |
|   |
|
|
|
| . | . | . | . | . | . | . | . | . |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   |
|   | . |
|   |
|
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
E | A | G | F | D | G | V | E | I | H | G | A | N | G | Y | L | I | D | Q | F | M | K | D | T | V | N | D | R | T | D | E | Y | G | G | S | L | Q | N | R | C | K | F | P | L | E | I | V | D | A | V | A | K | E | I | G | P | D | R | . |
V | G | I | R | L | S | P | F | A | D | Y | M | E | S | G | D | T | N | P | G | A |
Template Known Secondary structure |   |
 |  | T |
| S |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |
| T | T | T |
|
|
|
| S | T | T | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | . |  |  |  |  |  |
| T | T |
|
| T | T | T |
|
|
| S | S |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | C | E | E | I | A | Q | L | A | E | D | C | G | I | Q | A | L | T | I | H | G | R | T | R | A | C | L | F | N | G | E | A | E | Y | D | S | I | R | A | V | K | Q | K | V | S | I | P | V | I | A | N | G | D | I | T | D | P | L | K | A | R | A | V | L | D | Y | T | G | A | D | A | L | M | I | G | R | A | A | Q | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |
|   |
|
|
|
|
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|
|
|   |   |
|   |   | . |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|
|
Template Sequence |   |
L | G | L | Y | M | A | E | S | L | N | K | Y | G | I | L | Y | C | H | V | I | E | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | M | H | T | L | M | P | M | R | K | A | F | K | G | T | F | I | S | A | G | G | F | . |
T | R | E | D | G | N | E | A | V | S | K | G | R | T | D | L | V | A | Y | G | R | W | F | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | T | T | T |
| S |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | S | S |
| . |
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
. | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | W | I | F | R | E | I | Q | H | Y | L | D | T | G | E | L | L | P | P |
Query Conservation |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
N | P | D | L | P | K | R | F | Q | V | D | A | P | L | N | K | Y | D | R | P |
Template Known Secondary structure |   |
| T | T |  |  |  |  |  |  |  | T |
|
|
|
|
|
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
332 | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . |
  |