|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 50 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | G | Q | Y | Q | L | R | N | R | L | I | A | A | P | M | A | G | I | T | D | R | P | F | R | T | L | C | Y | E | M | G | A | G | L | T | V | S | E | M | M | S | S | N | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | V | W | E | S | D | K | S | R |
Query Conservation |   |
  |
|
|   |   |   |
|   |
|
|
|   |
|
|
|
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | F | A | N | A | K | F | A | N | P | F | M | N | A | S | G | V | H | C | M | T | I | E | D | L | E | E | L | K | A | S | Q | A | G | A | Y | I | T | K | S | S | T | L | E | K | R | E | G | N | P | L | P | R | Y | V | D | L | E | L | G | S | I | N | S | M | G | L | P | N | L | G | F | D | Y | Y | L | D | Y | V | L |
Template Known Secondary structure |   |
 |  | T | T |  |  |  | S | S | S |  |  |  |
| T | T | S | S |
| S | S |  |  |  |  |  |  |  |  |  | S | S |
| S |
|
| B |
|
|
| B |
| S | S |
| B |
|
| S |
| S |
|
|  |  |  |  | T | T |  |  |  |  |
|
|
|
|
| B | S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | |
. | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | M | V | H | I | D | E | P | G | I | R | T | V | Q | I | A | G | S | D | P | K | E | M | A | D | A | A | R | I | N | V | E | S | G | . |
A | Q | I | I | D | I | N | M | G | C | P | A | K | K | V | N | R | K | L | A | G | S | A | L | L | Q | Y | P | D | V | V | K | S | I | L | T | E | V | V | N | A | V | D | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
| . |   |
|   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
K | N | Q | K | E | N | A | Q | E | G | P | I | F | F | S | I | A | G | M | S | A | A | E | N | I | A | M | L | K | K | I | Q | E | S | D | F | S | G | I | T | E | L | N | L | S | C | P | N | V | . |
. |
. |
. |
. |
P | G | E | P | Q | L | A | Y | D | F | E | A | T | E | K | L | L | K | E | V | F | T | F | F | T | K |
Template Known Secondary structure |   |
 |  |  |  |  | T |
| S | S | S |
|
|  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| S |  |  |  |  |  | S |
|
|
|
| S | . | . | . | . | . | S | S |
|
|
| G | G | G |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
  |
  |   |
135 | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | T | L | K | I | R | T | G | W | A | P | E | H | R | N | C | E | E | I | A | Q | L | A | E | D | C | G | I | Q | A | L | T | I | H | G | R | T | R | A | C | L | F | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | A | E | Y | D | S | I | R | A | V | K | Q |
Query Conservation |   |
  |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | L | G | V | K | L | P | P | Y | . |
. |
F | D | L | V | H | F | D | I | M | A | E | I | L | N | Q | F | P | L | T | Y | V | N | S | V | N | S | I | G | N | G | L | F | I | D | P | E | A | E | S | V | V | I | K | P | K | D | G | F | G | G | I | G | G | A | Y | I | K | P | T | A | L | A | N | V | R | A | F | Y | T |
Template Known Secondary structure |   |
|  |  |  |  |  |
|
|
| . | . |
| S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|  |  | T | T | T | T |  |  | S |
| S | G | G | G | G |  |  |  |  |  | S | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
160 | . | . | . | . | . | . | . | . | |
|
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
  |
  |   |
192 | . | |
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | |
. | . | . | . | . | . | . | . | . | 240 | . | . |
Predicted Secondary structure |   |
 |
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | V | . |
. |
S | I | P | V | I | A | N | G | D | I | T | D | P | L | K | A | R | A | V | L | D | Y | T | G | A | D | A | L | M | I | G | R | A | A | Q | G | R | . |
P | W | I | F | R | E | I | Q | H | Y | L | D |
Query Conservation |   |
  |   | . | . |   |
|
|
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |
|   |
|   |
|
|
|
|
|   |   |
|   |
| . |
|   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |   |
|
|
|   |   |   |   |
|
|   |
|   |
|   |
| . |
|
|
|
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
Template Sequence |   |
R | L | K | P | E | I | Q | I | I | G | T | G | G | I | E | T | G | Q | D | A | F | E | H | L | L | C | . |
G | A | T | M | L | Q | I | G | T | A | L | H | K | E | G | P | A | I | F | D | R | I | I | K | E | L | E |
Template Known Secondary structure |   |
T | S |
| T | T | S |  |  |  |  |  | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  | . | T |
| S |  |  |  |  |
|  |  |  |  |  |  |
| T |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
238 | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |