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Job DescriptionP0ABT5
Confidence88.49%DateThu Jan 5 11:16:20 GMT 2012
Rank491Aligned Residues234
% Identity12%Templatec2cw6B_
PDB info PDB header:lyaseChain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria
Resolution2.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   23......30.........40.........50.........60.........70.........80.........90.........100..
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Query Sequence  RPFRTLCYEMGAGLTVSEMMSSNPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
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Template Sequence  IKLIDMLSEAGLSVIETTSFVSPKWVPQMGDHTEVLKGIQKFPGINYPVLTPNLKGF. . . . EAAVAAGAKEVVIFGAA. S
Template Known Secondary structure  TT
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TTT
GGGTTS


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   57..60.........70.........80.........90.........100.........110... ......120.........130 .
 
   103......110.........120.........130.........140..... ....150.........160.........170......
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Query Sequence  KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWA. . . . . . PEHRNCEEIAQLAEDCGIQALTIHGRTRACL
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Template Sequence  ELFTKKNINCSIEESFQRFDAILKAAQS. ANISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTI. . GV
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TTT.TT
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BTTTBS

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   132.......140.........150......... 160.........170.........180.........190.........200...... ..
 
   177..180.........190... ...... 200.........210.........220........ .230.........240..
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Query Sequence  FNGEAEYDSIRAVKQKV. SIPVIA. . . NGDITDPLKARAVLDYTGADALMIGRAAQ. . . . . . . . . . GRPWIFREIQHYLD
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Template Sequence  GTPGIMKDMLSAVMQEVPLAALAVHCHDTYGQALANTLMALQM. GVSVVDSSVAGLGGCPYAQGASGNLAT. EDLVYMLE
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GGGB
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   209210.........220.........230.........240.........250. ........260.........270........ .280......
 
   243......250.........260......
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Query Sequence  TGELLPPLPLAEVKRLLCAHVREL
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Template Sequence  GLGIHTGVNLQKLLEAGNFICQAL
Template Known Secondary structure  TT
B



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   287..290.........300.........310
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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