|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | S | V | I | I | V | G | G | G | M | A | G | A | T | L | A | L | A | I | S | R | L | S | H | G | A | L | P | V | H | L | I | E | A | T | A | P | E | S | H | A | H | P | G | F | D | G | R | A | I | A | L | . |
. |
. |
. |
. |
. |
. |
. |
A | A | G | T | C | Q | Q | L | A | R | I | G | V | W | Q | S | L | A | D | C |
Query Conservation |   |
  |
|
|   |
|
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|   | . | . | . |   |
|   |   |
|   |
|
|
|   |   |
|   |   |   |
|
|
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
L | D | L | L | I | I | G | G | G | I | T | G | A | G | V | A | V | Q | A | A | A | . |
. |
. |
S | G | I | K | T | G | L | I | E | X | Q | D | F | A | E | G | T | S | S | R | S | T | K | L | V | H | G | G | I | R | Y | L | K | T | F | D | V | E | V | V | A | D | T | V | G | E | R | A | V | V | Q | G | I | A | P | H |
Template Known Secondary structure |   |
B | S |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T |
|
|  |  |  |  |
| S | S | S | T | T |
| S | G | G | G | S | S |
| S |  |  |
|
|
| G | G | G | G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | |
|
|
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | A | I | T | T | V | H | V | S | D | R | G | H | A | G | F | V | T | L | A | A | E | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | Q | L | A | A | L | G | Q | V | V | E | L | H | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | P | K | P | D | P | X | L | L | P | I | Y | E | D | E | G | A | T | T | F | N | X | F | S | V | K | V | A | X | D | L | Y | D | K | L | A | N | V | T | G | T | K | Y | E | N | Y | T | L | T | P | E | E | V | L | E | R | E | P | F | L | K | K | E | G | L | K | G | A | G | V | Y | L | D | F | R | N | N | D | A | R |
Template Known Secondary structure |   |
S | S |  |  |
|
|  |  |  |  |  |  | S | S | S | S | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | S | T | T |
|
|  |  |  |
|  |  |  |  |  |  |  |
| T | T | S |
|
| T | T |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . |
  |
  |   |
111 | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
|
. |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
Query Sequence |   |
V | G | Q | R | L | F | A | L | L | R | K | A | P | G | V | T | L | H | C | P | D | R | V | A | N | V | A | R | T | Q | S | H | V | E | . |
. |
. |
. |
. |
. |
V | T | L | E | S | G | E | T | L | T | G | R | V | L | V | A | A | D | G | T | H | S | A | L | A | T | A | C | G | V | D | W | Q | Q | E | P | Y | . |
. |
E |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
Template Conservation |   |
|   |   |   |
|   |   |   |
|   |   |   | . |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
L | V | I | D | N | I | K | K | A | A | E | D | . |
G | A | Y | L | V | S | K | X | K | A | V | G | F | L | Y | E | G | D | Q | I | V | G | V | K | A | R | D | L | L | T | D | E | V | I | E | I | K | A | K | L | V | I | N | T | S | G | P | W | V | D | K | V | R | N | L | N | F | T | R | P | V | S | P | K | X | R | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | . | T |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | B | S |
|  |  |  |
|
| G | G | G |  |  |  |  |  | T | T |
|
| S | S |
|
|
|
|
| B |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | . | |
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
  |
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
. | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
. | . | . | . | . | . | . | . | 250 | . | . | |
|
. | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
Query Sequence |   |
Q | L | A | V | I | A | N | V | A | T | S | V | A | H | E | G | R | A | F | E | R | F | T | . |
. |
. |
Q | H | G | P | L | A | M | L | P | M | S | D | G | R | C | S | L | V | W | C | H | P | L | E | R | R | E | E | V | L | S | W | S | D | E | K | . |
. |
. |
F | C | R | E | L | Q | S | A | F | G | W | . |
. |
R | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |
|   |   |   |   |   |   | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
Template Conservation |   |
  |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |
Template Sequence |   |
T | K | G | I | H | L | V | V | D | A | K | K | L | P | V | P | Q | P | T | Y | F | D | T | G | K | Q | D | G | R | X | V | F | A | I | P | R | E | N | K | T | Y | F | G | T | T | D | T | D | Y | Q | G | D | F | T | D | P | K | V | T | Q | E | D | V | D | Y | L | L | D | V | I | N | H | R | Y | P | E | A | N | I | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | G | G | G | S |
|
| S | S |
|  |  |  |  |
| S | S | S | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |
|
|
|
|  |  |
|
| S |
| S | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T |
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | I | T | H | A | G | K | R | S | A | Y | P | L | A | L | T | H | A | A | R | S | I | T | H | R | T | V | L | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
L | A | D | I | E | A | S | W | A | G | L | R | P | L | L | I | G | S | S | L | E | R | E | P | D | G | L | L | T | L |
Template Known Secondary structure |   |
G | G | G |
|
|  |  |  |  |  |  |  |
|
| B |
|
|  |  |  |  |  |
| T | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
  |