|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | E | Y | T | N | H | S | D | T | T | F | A | L | R | N | I | S | F | R | V | P | G | R | T | L | L | H | P | L | S | L | T | F | P | A | G | K | V | T | G | L | I | G | H | N | G | S | G | K | S | T | L | L | K | . |
. |
. |
. |
. |
M | L | G | R | H | Q | P | P | S | E | G | E | I | L | L | D | A | Q | P | L | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   | . | . | . | . | . |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
P | H | T | P | R | E | P | A | G | W | L | E | L | N | G | V | T | . |
. |
. |
. |
. |
R | N | N | L | D | N | L | D | V | R | F | P | L | G | V | M | T | S | V | T | G | V | S | G | S | G | K | S | T | L | V | S | Q | A | L | V | D | A | L | A | A | H | F | G | Q | G | S | A | R | L | G | G | D | L | A | Q | I | T |
Template Known Secondary structure |   |
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  | T | T |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  | S | T | T | S | S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |
| S | S | G | G | G |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
493 | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . |
  |
  |   |
77 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
S | W | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |
|   |
|   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
R | L | V | R | V | D | Q | K | P | I | G | R | T | P | R | S | N | M | A | T | Y | T | G | L | F | D | Q | V | R | K | L | F | A | A | T | P | L | A | K | K | R | G | Y | N | A | G | R | F | S | F | N | V | K | G | G | R | C | E | H | C | Q | G | E | G | W | V | M | V | P | S | V | Y | A | P | C | P | V | C | H | G |
Template Known Secondary structure |   |
 |  |  |  |  |
| S | S |
| S |
| S | S | T | T |
|
|  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T | S | S | T |  |  |  |  | S |
|
|
| T | T | S | S |
| S | S | S | S | S | S | B |
| S | S | S | T | T |
|
|  |  |  |
|
|
|
|  |  |  |
| T | T | T | S | S |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
585 | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . |
  |
  |   |
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | |
. | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
S | K | A | F | A | R | K | V | A | Y | L | P | Q | Q | L | P | P | A | E | G | M | T | V | R | E | L | V | A | I | G | R | Y | P | W | H | G | A | L | G | R | F | G | A | A | D | R | E | K | V | E | E | A | I | S | L | V | G | L | K | . |
P | L | A | H | R | L | V | D | S | L | S | G | G | E | R | Q | R | A |
Query Conservation |   |
. | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   | . |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |   |   |   |
|
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|
Template Sequence |   |
T | R | Y | N | A | E | T | L | E | V | E | Y | R | G | K | N | I | A | D | V | L | A | L | T | V | D | E | A | H | D | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | A | D | E | S | A | I | F | R | A | L | D | T | L | R | E | V | G | L | G | Y | L | R | L | G | Q | P | A | T | E | L | S | G | G | E | A | Q | R | I |
Template Known Secondary structure |   |
S |
| B |
| T | T | G | G | G |
|
| S | S | S |
|
|  |  |  |  |  | T |
| B |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S | B | T | T |
|
| G | G | G |
|
| S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . |
  |
  |   |
157 | . | . | 160 | . | . | . | . | . | . | . | |
|
|
. | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
W | I | A | M | L | V | A | Q | D | S | R | . |
. |
. |
C | L | L | L | D | E | P | T | S | A | L | D | I | A | H | Q | V | D | V | L | S | L | V | H | R | L | S | Q | E | R | G | L | T | V | I | A | V | L | H | D | I | N | M | A | A | R | Y | C | D | Y | L | V | A | L | . |
. |
. |
. |
. |
. |
R | G | G | E | M | I |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|   | . | . | . |
|
|
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|
| . | . | . | . | . | . |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   | . |
|   |
|
|
|
|
|
|
|
|
|   |   |
| . |   |   |
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |
|   |
|
|
Template Sequence |   |
K | L | A | T | E | L | R | R | S | G | R | G | G | T | V | Y | V | L | D | E | P | T | T | G | L | H | P | A | D | V | E | R | L | Q | R | Q | L | V | K | L | V | D | A | . |
G | N | T | V | I | A | V | E | H | K | M | Q | V | V | . |
A | A | S | D | W | V | L | D | I | G | P | G | A | G | E | D | G | G | R | L | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |  |
| S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T |
|  |  |  |  |  |
|
|
|  |  |  |  | . | T | T |
| S |  |  |  |  |  |
| S | S | S | G | G | G |
|
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  | . |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | |
. | . | . | . | . | . | . | 790 | . | . | . | . | . | . | |
. | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | G | T | P | A | E | I | M | R | G | E |
Query Conservation |   |
  |   |
|   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |
|
|   |   |   |   |
Template Sequence |   |
A | Q | G | T | P | A | E | V | A | Q | A | A |
Template Known Secondary structure |   |
 |  |  | S |  |  |  |  |  | T |
| S |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
818 | . | 820 | . | . | . | . | . | . | . | . | . |
  |