|   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | L | R | A | Q | L | N | E | G | L | R | A | A | Y | L | L | L | G | N | D | P | L | L | L | Q | E | S | Q | D | A | V | R | Q | V | A | A | A | Q | G | F | E | E | H | H | T | F | S | I | D | P | N | T | D | W | N | A | I | F | S | L | C | . |
. |
. |
. |
. |
. |
Q | A | M | S | L | F | A | S | R | Q | T | L |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |   |
|   |
|
|
|   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
T | T | V | R | K | F | V | D | E | G | K | L | P | H | L | L | F | Y | G | P | P | G | T | G | K | T | S | T | I | V | A | L | A | R | E | I | Y | G | K | N | Y | S | N | M | V | L | E | L | N | A | S | D | D | R | G | I | D | V | V | R | N | Q | I | K | D | F | A | S | T | R | Q | I | F | S | K | G | F | K | L | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |
| S | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |
| T | T | S |
|
| S |  |  |  |  |  | T |  |  |  |  |  |  |  | S |
|
| S | S | S |
| S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | L | L | P | E | N | G | P | N | A | A | I | N | E | Q | L | L | T | L | T | G | L | L | H | D | D | L | L | L | I | V | R | G | N | K | L | S | K | A | Q | E | N | A | A | W | F | T | A | L | A | N | R | S | V | Q | V | T | C | Q | T | P | E | Q | A | Q | L | P | R | W | V | A | A | R | A | K | Q | L | N | L |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
I | L | D | E | A | D | A | M | T | N | A | A | Q | N | A | L | R | R | V | I | E | R | . |
Y | T | K | N | T | R | F | C | V | L | A | N | Y | A | H | K | L | T | P | . |
. |
. |
. |
. |
. |
A | L | L | S | Q | C | T | R | F | R | F | Q | P | L | P | Q | E | A | I | E | R | R | I | A | N | V | L | V | H | E | K | L |
Template Known Secondary structure |   |
 |  | T | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | T | T | T | T |  |  |  |  |  |  |  | S |
| G | G | G | S |
|  | . | . | . | . | . | . |  |  |  | T | T | S |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
115 | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
. | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . |
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
|
|
. | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | L | D | D | A | A | N | Q | V | L | C | Y | C | Y | E | G | N | L | L | A | L | A | Q | A | L | E | R | L | S | L | L | W | P | D | . |
. |
. |
G | K | L | T | L | P | R | V | E | Q | A | V | N | D | A | A | H | F | T | P | F | H | W | V | D | A | L | L | M | G | K | S | K | R | A | L | H | I | L | Q | Q | L | R |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   | . | . | . |   |   |
|   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Template Sequence |   |
K | L | S | P | N | A | E | K | A | L | I | E | L | S | N | G | D | M | R | R | V | L | N | V | L | Q | S | C | K | A | T | L | D | N | P | D | E | D | E | I | S | D | D | V | I | Y | E | C | C | G | A | P | R | P | S | D | L | K | A | V | L | K | S | I | L | E | D | D | W | G | T | A | H | Y | T | L | N | K | V | R |
Template Known Secondary structure |   |
| B |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T | T | T | T | T | T | T |
| S | S | S |
|
|
| B |
|  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . |
  |
  |   |
238 | |
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | . |
E | G | S | E | P | V | I | L | L | R | T | L | Q | R | E | L | L | L | L | V | N | L | K | R | Q | S | A | H | T | P | L | R | A | L | F | D | K | H | R | V | W | Q | N | R | R | G | M | M | G | E | A | L | N | R | L | S | Q | T | Q | L | R | Q | A | V | Q | L | L | T | R | T | E | L | T | L | K | Q | D | Y |
Query Conservation |   |
  | . |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| . | . |   |   |
Template Sequence |   |
S | A | K | G | L | A | L | I | D | L | I | E | G | I | V | K | I | L | E | D | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | Q | N | E | E | T | R | V | H | L | L | T | K | L | A | D | I | E | Y | S | I | . |
. |
S | K |
Template Known Secondary structure |   |
 | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T | T |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
268 | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
|
. | . |
  |
  |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | S | V | W | A | E | L | E | G | L | S | L | L | L |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
Template Sequence |   |
G | G | N | D | Q | I | Q | G | S | A | V | I | G | A | I |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . |
  |