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Job DescriptionP77650
Confidence100.00%DateThu Jan 5 12:31:22 GMT 2012
Rank51Aligned Residues379
% Identity17%Templatec2cfyB_
PDB info PDB header:oxidoreductaseChain: B: PDB Molecule:thioredoxin reductase 1; PDBTitle: crystal structure of human thioredoxin reductase 1
Resolution2.7 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50..
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Query Sequence  EKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYERPPLSKSML. . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  DYDLIIIGGGSGGLAAAKEAAQYGK. . KVMVLDFVTPTPLGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSRNYGWK
Template Known Secondary structure  S

STTT
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TT




TTSTT

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   12.......20.........30...... ...40.........50.........60.........70.........80.........
 
   53......60.........70.........80.........90.... .....100.........110......
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Query Sequence  . . . . . . . . . . . . . . . LEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLT. NGESWHWDQLFIATGAAARPLP
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Template Conservation                                                                                  
Template Sequence  VEETVKHDWDRMIEAVQNHIGSLNWGYRVALREKKVVYENAYGQFIGPHRIKATNNKGKEKIYSAERFLIATGERPRYLG
Template Known Secondary structure 

SS



TT

TTTTS






S
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   90.........100.........110.........120.........130.........140.........150.........160.........
 
   117..120.........130.........140.........150.........160.........170.........180.........190......
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Query Sequence  LLDALGERCFTLRHAGDAARLREVLQPERSVVIIGAGTIGLELAASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRH
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Template Sequence  IP. . . . . . . GDKEYCISSDDLFSLPYCPGKTLVVGASYVALECAGFLAGIGLDVTVMVRSILL. . RGFDQDMANKIGEHM
Template Known Secondary structure  ST.......T
B
TT
SS


S

STT

SS
SS..TTS
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   170. ........180.........190.........200.........210.........220..... ....230.........240
 
   197..200.........210...... ...220.........230.........240.........250... ......260.
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Query Sequence  QQAGVRILLNNAIEHVVDGE. . . . . . . . . . KVELTLQSGETLQADVVIYGIGISANEQLAREANLDT. . . . . ANGIVIDE
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Template Sequence  EEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVGVKINEKTGKIPVTD
Template Known Secondary structure  TT
S
STT
SSSS
S
S
S
SSS
GGGTT



TTT

B


T
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   241........250.........260.........270.........280.........290.........300.........310.........320
 
   262.......270.........280.........290.........300........ .310.........320.........330.......
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Query Sequence  ACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNQAQIAAAAMLG. LPLPLLPPPWFWSDQYSDNLQFIGDMRGD. . .
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Template Sequence  EEQTNVPYIYAIGDILEDK. . . . . . . . VELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGACGLSEEKAVE
Template Known Secondary structure  TSB
SSTT
STTBTTS........


S







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SSS


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   321........330......... 340.........350.........360.........370.........380.........390..
 
   338.340.........350...... ...360....... ..370.........380..... ....390....
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Query Sequence  . . . . . . . . . . . . . . . . . . . DWLCRGNPETQKAIWFNLQ. NGVLIGAVTLN. . QGREIRPIRKWIQSGKTF. DAKLLIDEN
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Template Conservation                                 

         


    
  
   
     

    
   
       
Template Sequence  KFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKIICNTKDNERVVGFHVLGPNAGEVTQGFAAALKCGLTKKQLDSTIGIH
Template Known Secondary structure 
GGG

GGGTTTT

TT
GGGTTSTTTT
BS


T
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   393......400.........410.........420.........430.........440.........450.........460.........470..
 
   395....400
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Query Sequence  IALKSL
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Template Conservation 
     
Template Sequence  PVCAEV
Template Known Secondary structure  T
GGGG
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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