Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	S	Y	Y	F	Q	G	L	A	L	G	A	A	M	I	L	P	L	G	P	Q	N	A	F	V	M	N	Q	G	I	R	R	Q	Y	H	I	M	I	A	L	L	C	A	I	S	D	L	V	L	I	C	A	G	I	F	G	G	S	A
Secondary structure
SS confidence
Disorder		?																														?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		L	L	M	Q	S	P	W	L	L	A	L	V	T	W	G	G	V	A	F	L	L	W	Y	G	F	G	A	F	K	T	A	M	S	S	N	I	E	L	A	S	A	E	V	M	K	Q	G	R	W	K	I	I	A	T	M	L	A	V	T	W
Secondary structure
SS confidence
Disorder																															?		?	?	?	?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		L	N	P	H	V	Y	L	D	T	F	V	V	L	G	S	L	G	G	Q	L	D	V	E	P	K	R	W	F	A	L	G	T	I	S	A	S	F	L	W	F	F	G	L	A	L	L	A	A	W	L	A	P	R	L	R	T	A	K	A	Q
Secondary structure
SS confidence
Disorder																?	?	?	?	?	?	?																																					?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.
Sequence		R	I	I	N	L	V	V	G	C	V	M	W	F	I	A	L	Q	L	A	R	D	G	I	A	H	A	Q	A	L	F	S
Secondary structure
SS confidence
Disorder																															?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2voy chain B Region: 100 - 137 Aligned: 38 Modelled: 38 Confidence: 18.6% Identity: 8% PDB header:hydrolase Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus Phyre2 PDB 3eh4 chain A Region: 68 - 136 Aligned: 69 Modelled: 69 Confidence: 11.9% Identity: 9% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase subunit 1; PDBTitle: structure of the reduced form of cytochrome ba3 oxidase from thermus2 thermophilus Phyre2 PDB 1xme chain A domain 1 Region: 68 - 136 Aligned: 69 Modelled: 69 Confidence: 9.2% Identity: 9% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 1q90 chain G Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 5.9% Identity: 29% Fold: Single transmembrane helix Superfamily: PetG subunit of the cytochrome b6f complex Family: PetG subunit of the cytochrome b6f complex Phyre2 PDB 1q90 chain G Region: 1 - 14 Aligned: 14 Modelled: 14 Confidence: 5.9% Identity: 29% PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii Phyre2 PDB 2d1k chain C Region: 18 - 35 Aligned: 18 Modelled: 18 Confidence: 5.5% Identity: 17% PDB header:structural protein Chain: C: PDB Molecule:metastasis suppressor protein 1; PDBTitle: ternary complex of the wh2 domain of mim with actin-dnase i Phyre2 PDB 1eys chain L Region: 67 - 136 Aligned: 70 Modelled: 70 Confidence: 5.3% Identity: 7% Fold: Bacterial photosystem II reaction centre, L and M subunits Superfamily: Bacterial photosystem II reaction centre, L and M subunits Family: Bacterial photosystem II reaction centre, L and M subunits Phyre2 PDB 1xio chain A Region: 18 - 176 Aligned: 145 Modelled: 145 Confidence: 5.1% Identity: 10% Fold: Family A G protein-coupled receptor-like Superfamily: Family A G protein-coupled receptor-like Family: Bacteriorhodopsin-like Phyre2 PDB 1xio chain A Region: 18 - 176 Aligned: 145 Modelled: 145 Confidence: 5.1% Identity: 10% PDB header:signaling protein Chain: A: PDB Molecule:anabaena sensory rhodopsin; PDBTitle: anabaena sensory rhodopsin Phyre2 1 c2voyB_ 2 c3eh4A_ 3 d1xmea1 4 d1q90g_ 5 c1q90G_ 6 c2d1kC_ 7 d1eysl_ 8 d1xioa_ 9 c1xioA_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2voyB_ 18.6 8 PDB header:hydrolase Chain: B: PDB Molecule:sarcoplasmic/endoplasmic reticulum calcium PDBTitle: cryoem model of copa, the copper transporting atpase from2 archaeoglobus fulgidus 2 c3eh4A_ 11.9 9 PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase subunit 1; PDBTitle: structure of the reduced form of cytochrome ba3 oxidase from thermus2 thermophilus 3 d1xmea1 9.2 9 Fold:Cytochrome c oxidase subunit I-like Superfamily:Cytochrome c oxidase subunit I-like Family:Cytochrome c oxidase subunit I-like 4 d1q90g_ 5.9 29 Fold:Single transmembrane helix Superfamily:PetG subunit of the cytochrome b6f complex Family:PetG subunit of the cytochrome b6f complex 5 c1q90G_ 5.9 29 PDB header:photosynthesis Chain: G: PDB Molecule:cytochrome b6f complex subunit petg; PDBTitle: structure of the cytochrome b6f (plastohydroquinone : plastocyanin2 oxidoreductase) from chlamydomonas reinhardtii 6 c2d1kC_ 5.5 17 PDB header:structural protein Chain: C: PDB Molecule:metastasis suppressor protein 1; PDBTitle: ternary complex of the wh2 domain of mim with actin-dnase i 7 d1eysl_ 5.3 7 Fold:Bacterial photosystem II reaction centre, L and M subunits Superfamily:Bacterial photosystem II reaction centre, L and M subunits Family:Bacterial photosystem II reaction centre, L and M subunits 8 d1xioa_ 5.1 10 Fold:Family A G protein-coupled receptor-like Superfamily:Family A G protein-coupled receptor-like Family:Bacteriorhodopsin-like 9 c1xioA_ 5.1 10 PDB header:signaling protein Chain: A: PDB Molecule:anabaena sensory rhodopsin; PDBTitle: anabaena sensory rhodopsin

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Transmembrane helix prediction

Transmembrane helices have been predicted in your sequence to adopt the topology shown below

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0