Job Description P0AFI0 Confidence 100.00% Date Thu Jan 5 11:26:22 GMT 2012 Rank 22 Aligned Residues 505 % Identity 19% Template c2w93A_ PDB info PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide Resolution 1.60 Å

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		8	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.		.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.
Predicted Secondary structure																																							.
Query SS confidence																																							.
Query Sequence		T	D	G	M	H	I	I	V	E	A	L	K	Q	N	N	I	D	T	I	Y	G	V	V	G	I	P	V	T	D	M	A	R	H	A	Q	A	E	.	G	I	R	Y	I	G	F	R	H	E	Q	S	A	G	Y	A	A	A	A	S	G	F	L	T	Q	K	P	G	I	C	L	T	V	S	A	P	G	F	L	N	G	L
Query Conservation																																							.
Alig confidence																																							.																												.
Template Conservation																																																																			.
Template Sequence		I	T	L	G	K	Y	L	F	E	R	L	K	Q	V	N	V	N	T	V	F	G	L	P	G	D	F	N	L	S	L	L	D	K	I	Y	E	V	E	G	M	R	W	A	G	N	A	N	E	L	N	A	A	Y	A	A	D	G	Y	A	R	I	K	G	M	S	.	C	I	I	T	T	F	G	V	G	E	L	S	A	L
Template Known Secondary structure															T	T										G	G	G						G	G	G	G	S	T	T							S																	S			.						T	T
Template Predicted Secondary structure																																																																			.
Template SS confidence
		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.		.	70	.	.	.	.	.	.	.	.	.	80	.	.
		87	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.							.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
Predicted Secondary structure																													.	.	.	.	.	.
Query SS confidence																													.	.	.	.	.	.
Query Sequence		T	A	L	A	N	A	T	V	N	G	F	P	M	I	M	I	S	G	S	S	D	R	A	I	V	D	L	.	.	.	.	.	.	Q	Q	G	D	Y	E	E	L	D	Q	M	N	A	A	K	P	Y	A	K	A	A	F	R	V	N	Q	P	Q	D	L	G	I	A	L	A	R	A	I	R	V	S	V	S	G	R	P	G
Query Conservation																													.	.	.	.	.	.
Alig confidence																													.	.	.	.	.	.																																														.
Template Conservation																																																																																.
Template Sequence		N	G	I	A	G	S	Y	A	E	H	V	G	V	L	H	V	V	G	V	P	S	I	S	S	Q	A	K	Q	L	L	L	H	H	T	L	G	N	G	D	F	T	V	F	H	R	M	S	A	N	I	S	E	T	T	A	M	I	T	D	I	A	T	A	P	A	E	I	D	R	C	I	R	T	T	Y	V	T	Q	.	R
Template Known Secondary structure										T	T																	T	T				T	T	S		S	S	S		S	S								T	T		S								T	T	T																T	.	S
Template Predicted Secondary structure																																																																																.
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160		.
		161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Predicted Secondary structure
Query SS confidence
Query Sequence		G	V	Y	L	D	L	P	A	N	V	L	A	A	T	M	E	K	D	E	A	L	T	T	I	V	K	V	E	N	P	S	P	A	L	L	P	C	P	K	S	V	T	S	A	I	S	L	L	A	K	A	E	R	P	L	I	I	L	G	K	G	A	A	Y	S	Q	A	D	E	Q	L	R	E	F	I	E	S	A	Q	I
Query Conservation
Alig confidence																		.
Template Conservation																		.
Template Sequence		P	V	Y	L	G	L	P	A	N	L	V	D	L	N	V	P	.	A	K	L	L	Q	T	P	I	D	M	S	L	K	P	N	D	A	E	S	E	K	E	V	I	D	T	I	L	A	L	V	K	D	A	K	N	P	V	I	L	A	D	A	C	C	S	R	H	D	V	K	A	E	T	K	K	L	I	D	L	T	Q	F
Template Known Secondary structure									T	T	G	G	G	S				.	G	G	G	G	G	S					S																								S	S												T	T
Template Predicted Secondary structure																		.
Template SS confidence
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.		.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.									.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																							.	.	.	.	.	.	.	.
Query SS confidence																							.	.	.	.	.	.	.	.
Query Sequence		P	F	L	P	M	S	M	A	K	G	I	L	E	D	T	H	P	L	S	A	A	.	.	.	.	.	.	.	.	A	A	R	S	F	A	L	A	N	A	D	V	V	M	L	V	G	A	R	L	N	W	L	L	A	H	G	K	K	G	W	A	A	D	T	Q	F	I	Q	L	D	I	E	P	Q	E	I	D	S	N	R
Query Conservation																							.	.	.	.	.	.	.	.
Alig confidence																							.	.	.	.	.	.	.	.																						.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		P	A	F	V	T	P	M	G	K	G	S	I	D	E	Q	H	P	R	Y	G	G	V	Y	V	G	T	L	S	K	P	E	V	K	E	A	V	E	S	A	D	L	I	L	S	V	G	A	L	T	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	I	V	E	F	H	S	D	H	M	K	I	R	N	A	T
Template Known Secondary structure							T	T	T	T	T	S	S		T	T	S	T	T							G	G	G	S										T		S						S					.	.	.	.	.	.	.	.	.	.	.	.	.	.							S	S					T	T
Template Predicted Secondary structure																																																				.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		241	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290															.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	I	A	V	P	V	V	G	D	I	A	S	S	M	Q	G	M	L	A	E	L	K	Q	N	T	F	T	T	P	L	V	W	R	D	I	L	N	I	H	K	Q	Q	N	A	Q	K	M	H	E	K	L	S	T	D	T	Q	P	L	N	Y	F	N	A	L	S	A	V	R	D	V	L	R	E	N	Q	D	I	Y	L	V
Query Conservation
Alig confidence																														.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template Conservation																														.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template Sequence		F	P	G	V	Q	M	K	F	V	L	Q	K	L	L	T	N	I	A	D	A	A	K	G	Y	K	P	V	A	.	.	.	.	.	.	.	.	.	.	.	.	.	V	P	A	R	T	P	A	N	A	A	V	P	A	S	T	P	L	K	Q	E	W	M	W	N	Q	L	G	N	F	L	Q	E	G	.	D	V	V	I	A
Template Known Secondary structure				T																		T	T	T						.	.	.	.	.	.	.	.	.	.	.	.	.													T	T		B										G	G	G	T			T	T	.
Template Predicted Secondary structure																														.	.	.	.	.	.	.	.	.	.	.	.	.																																		.
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.														.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.		.	.	.	.	.
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.						.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.
Predicted Secondary structure																																														.	.	.	.	.
Query SS confidence																																														.	.	.	.	.
Query Sequence		N	E	G	A	N	T	L	D	N	A	R	N	I	I	D	M	Y	K	P	R	R	R	L	D	C	G	T	W	G	V	M	G	I	G	M	G	Y	A	I	G	A	S	V	T	.	.	.	.	.	S	G	S	P	V	V	A	I	E	G	D	S	A	F	G	F	S	G	M	E	I	E	T	I	C	R	Y	N	L	P	V
Query Conservation																																														.	.	.	.	.
Alig confidence													.	.																																.	.	.	.	.
Template Conservation													.	.
Template Sequence		E	T	G	T	S	A	F	G	I	N	Q	.	.	T	T	F	P	N	N	T	Y	G	I	S	Q	V	L	W	G	S	I	G	F	T	T	G	A	T	L	G	A	A	F	A	A	E	E	I	D	P	K	K	R	V	I	L	F	I	G	D	G	S	L	Q	L	T	V	Q	E	I	S	T	M	I	R	W	G	L	K	P
Template Known Secondary structure			T	T						G	G	G	.	.	S				S	S							T	T	T			T	T																		T	T																T	T								T	T
Template Predicted Secondary structure													.	.
Template SS confidence
		387	.	.	390	.	.	.	.	.	.	.			.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
		468	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.				.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530			.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure																																																	.	.	.																	.	.
Query SS confidence																																																	.	.	.																	.	.
Query Sequence		T	I	V	I	F	N	N	G	G	I	Y	R	G	D	G	V	D	L	S	G	A	G	A	P	S	P	T	D	L	L	H	H	A	R	Y	D	K	L	M	D	A	F	R	G	V	G	Y	.	.	.	N	V	T	T	T	D	E	L	R	H	A	L	T	T	G	I	.	.	Q	S	R	K	P	T	I	I	N	V	V	I
Query Conservation																																																	.	.	.																	.	.
Alig confidence																			.	.	.	.																											.	.	.																	.	.
Template Conservation																			.	.	.	.
Template Sequence		Y	L	F	V	L	N	N	D	G	Y	T	I	Q	K	L	I	H	.	.	.	.	G	P	K	A	Q	Y	N	E	I	Q	G	W	D	H	L	S	L	L	P	T	F	G	A	K	D	Y	E	T	H	R	V	A	T	T	G	E	W	D	K	L	T	Q	D	K	S	F	N	D	N	S	K	I	R	M	I	E	V	M	L
Template Known Secondary structure								S	S	S						T	T	S	.	.	.	.		T	T		G	G	G							G	G	G					T	T		S	S								B									T		T	T	T	T	S			S
Template Predicted Secondary structure																			.	.	.	.
Template SS confidence
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.					.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
		543	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	P	A	A	G	T	E
Query Conservation
Alig confidence
Template Conservation
Template Sequence		P	V	F	D	A	P	Q
Template Known Secondary structure			T	T
Template Predicted Secondary structure
Template SS confidence
		541	.	.	.	.	.	.