|   |
46 | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |
|
|
|
|  |  |  |
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | N | C | M | G | L | T | F | K | N | P | L | G | L | A | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | L | D | K | D | G | E | C | I | D | A | L | G | A | M | G | F | G | S | I | E | I | G | T | V | T | P | R | P | Q | P | G | N | D | K | P | R | L | F | R | L | V | D | A | E | G | L | I | N | R | M | G | F |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|   |
|   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
| . | . | . | . | . | . |
Template Sequence |   |
P | L | K | V | G | A | V | T | A | P | N | R | V | F | M | A | P | L | T | R | L | R | S | I | E | P | G | D | I | P | T | P | L | M | G | E | Y | Y | R | Q | R | A | S | A | G | L | I | I | S | E | A | T | Q | I | S | A | . |
Q | A | K | G | Y | A | G | A | P | G | L | H | S | P | E | Q | I | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|  |  |  | T | T |  |  |  | S | S | S |  |  |  |
|
|
|
|
|
|
|
| B | T | T | T | T | B |
|
|  |  |  |  |  |  |  |  |  | T | T | T | S | S |  |  |  |  |  |  |  |  | S | S | S | . | T | T |
|
| S | T | T |
|
| B | S | S | S |  |  |  |  | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
|
|
  |
  |   |
116 | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 150 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
N | N | L | G | V | D | N | L | V | E | N | V | K | K | A | H | Y | D | G | V | L | G | I | N | I | G | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | K | D | T | P | V | E | Q |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
. |
. |
A | A | W | K | K | I | T | A | G | V | H | A | E | D | G | R | I | A | V | Q | L | W | H | T | G | R | I | S | H | S | S | I | Q | P | G | G | Q | A | P | V | S | A | S | A | L | N | A | N | T | R | T | S | L | R | D | E | N | G | N | A | I | R | V | D | T | T | T | P | R | A | L | E | L | D | E | I | P | G |
Template Known Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
|
| T | T | S | S |
| G | G | G | S | G | G | G |
|
|
|  |  | S | S | S |
|
|
|
| S |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|
|
|
|  |  |
|
| G | G | G |  |  |  |
Template Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
151 | . | . | . | . | . | . | . | . | 160 | . | . | |
. | . | . | . | . | . | . | 170 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | D | D | Y | L | I | C | M | E | K | I | . |
Y | A | Y | A | G | Y | I | A | I | N | I | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
S | P | N | T | P | G | L | R | T | L | Q | Y | G | E | A | L | D | D | L | L | T | A | I | K | N | K | Q | N | D | L | Q | A | M | H | H | K | Y | V | P | I | A | V | K | I | A | P |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   | . |   |   |   |
|
|   |
|   |
|
|   |   | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|   |   |
|
|   |
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
| . |   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |   |
|   |   | . |   |
|   |   |
|
|
|   |
Template Sequence |   |
I | V | N | D | F | R | Q | A | V | A | N | A | R | E | A | G | F | D | L | V | E | L | H | S | A | H | G | Y | L | L | H | Q | F | L | S | P | . |
S | S | N | Q | R | T | D | Q | Y | G | G | S | V | E | N | R | A | R | L | V | L | E | V | V | D | A | V | C | N | E | W | S | A | D | . |
R | I | G | I | R | V | S | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |
| T | . | T | T |
|
|
|
| S | T | T | S | S | S |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| G | G | . | G |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | |
. | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
. | 230 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | S | E | E | E | L | I | Q | V | A | D | S | L | V | R | H | N | I | D | G | V | I | A | T | N | T | T | L | D | R | S | L | V | Q | G | M | K | N | C | D | Q | T | G | G | L | S | G | R | P | L | Q | L | K | S | T | E | I | I | R | R | L | S | L | E | L | N | G | R | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   | . | . |   |   |
Template Sequence |   |
I | G | T | F | Q | N | V | D | N | G | P | N | E | E | A | D | A | L | Y | L | I | E | E | L | A | K | R | G | I | A | Y | L | H | M | S | E | T | D | L | A | G | G | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | Y | S | E | A | F | R | Q | K | V | R | E | R | F | . |
. |
H | G |
Template Known Secondary structure |   |
S | S |
| B | T | T | B |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |
|
| B | T | T | B |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
237 | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | |
|
. | . |
  |
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | I | I | G | V | G | G | I | D | S | V | I | A | A | R | E | K | I | A | A | G | . |
A | S | L | V | Q | I | Y | S | G | F | I | F | K | G | P | P | L | I | K | E | I | V | T | H |
Query Conservation |   |
|
|
|   |   |
|
|
|   |   |
|   |
|
|   |
|   |
|   |   |
| . |
|
|   |
|   |
|   |
|   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
| . |   |   |
|   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|
| . |
|
|
|
|   |   |
|   |   |   |
|
Template Sequence |   |
V | I | I | G | A | G | . |
A | Y | T | A | E | K | A | E | D | L | I | G | K | G | L | I | D | A | V | A | F | G | R | D | Y | I | A | . |
N | P | D | L | V | A | R | L | Q | K | K |
Template Known Secondary structure |   |
 |  |  |  |  | S | . | S |
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  | S |  |  |  |  |  | . |
| T | T |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
| . |
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
296 | . | . | . | 300 | . | |
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
. | 330 | . | . | . | . | . | . | . | . | . |
  |