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Job DescriptionP0A7E1
Confidence100.00%DateThu Jan 5 11:05:27 GMT 2012
Rank4Aligned Residues326
% Identity41%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
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Query Sequence  MYYPFVRK. ALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGF
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Template Sequence  FYAEHLMPTLQGLLDPESAHRLAV. RFTSLGLLP. F. . . . QDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGF
Template Known Secondary structure  TS
.TT


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GGG
TTSSS
TTTTTTSS
TT
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   37..40.........50.........60 ......... 70 .........80.........90.........100.........110
 
   80.........90.........100.........110.........120....... ..130.........140.........150.
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Query Sequence  GSIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENV. . . . . . . . KKAHYDGVLGINIGKNKDTPVEQG
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Template Sequence  GFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSV. . DA
Template Known Secondary structure  S
SS
B

S
S

GGGT




B

TTTT




TT
S..
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   114.....120.........130.........140.........150.........160.........170.........180......... 190.
 
   152.......160.........170.........180.........190.........200.........210.........220.........230.
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Query Sequence  KDDYLICMEKIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVA
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Template Sequence  AEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKV. . LQERDGLRRVHRPAVLVKIAPDLTSQDKEDIA
Template Known Secondary structure  GGG
S


TTSTTSGGGGS..TS
GGG


S


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   192.......200.........210.........220.........230....... ..240.........250.........260.........
 
   232.......240.........250.........260.........270.........280.........290.........300.........310.
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Query Sequence  DSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAG
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Template Sequence  SVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAG
Template Known Secondary structure  T




BS


TT


TTTTSSSTTT
S
SS

ST
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   270.........280.........290.........300.........310.........320.........330.........340.........
 
   312.......320.........330......
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Query Sequence  ASLVQIYSGFIFKGPPLIKEIVTHI
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Template Sequence  ASLVQLYTALTFWGPPVVGKVKREL
Template Known Secondary structure 
SS
T
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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