|   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |
|
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | P | E | R | A | H | E | F | T | F | Q | Q | L | R | R | I | T | G | T | P | F | E | A | L | V | R | Q | K | V | P | A | K | P | V | N | C | M | G | L | T | F | K | N | P | L | G | L | A | A | . |
. |
. |
. |
. |
. |
. |
G | L | D | K | D | G | E | C | I | D | A | L | G | A | M | G | F | G | S | I | E | I | G | T |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |
|
|
|
|
|
| . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|   |
| . |
|   |
|   |   |   |   |   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |   | . |   |
|
|   |
Template Sequence |   |
G | D | E | W | T | K | R | A | N | D | R | A | W | K | H | K | L | L | Y | P | . |
R | L | A | Q | D | V | E | A | P | D | T | S | T | E | I | L | G | H | K | I | K | A | P | F | I | M | A | P | I | A | A | H | G | L | A | H | T | T | K | E | A | G | T | A | R | A | V | S | E | F | G | T | I | M | . |
S | I | S | A |
Template Known Secondary structure |   |
T | T | S |  |  |  |  |  |  |  |  | G | G | G | G |  |  |  |
|
| . |
|
| S |
|
|
|
| S |
| B |
|
|  |  |  | T | T |  |  |  | S | S | S |  |  |  |
|
|
| S |
| G | G | G | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|  | . |  |  |  | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1046 | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | |
. | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | |
1120 | . | . | . |
  |
  |   |
87 | . | . | 90 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | P | R | P | . |
. |
. |
. |
. |
Q | P | G | N | D | K | P | R | L | F | R | L | V | D | A | E | G | L | I | N | R | M | G | F | N | N | L | G | V | D | N | L | V | E | N | V | K | K | A | H | Y | D | G | V | L | G | I | N | I | G | K | N | K | D | T | P | V | E | Q | G | K | D | D | Y | L | I | C | M | E | K |
Query Conservation |   |
|
|   |   |   | . | . | . | . | . |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
| . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |
|   |
|   |   |
|   |   |   |   | . | . | . | . | . | . | . |
Template Sequence |   |
Y | S | G | A | T | F | E | E | I | S | E | G | L | N | G | G | P | R | W | F | Q | I | Y | M | A | K | D | . |
. |
. |
. |
. |
. |
. |
. |
D | Q | Q | N | R | D | I | L | D | E | A | K | S | D | G | A | T | A | I | I | L | T | A | D | S | T | V | S | G | N | R | D | R | D | V | K | N | K | . |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
T |
| S | S |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
|
|
| S | S | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |
| S |
| S | S |
|
|
|
|  |  |  |  |  | T | T | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1124 | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | Y | A | Y | A | G | Y | I | A | I | N | I | S | S | P | N | T | P | G | L | R | T | L | Q | Y | G | E | A | L | D | D | L | L | T | A | I | K | N | K | Q | N | D | L | Q | A | M | H | H | K | Y | V | P | I | A | V | K | I | A | P | D | L | S | E | E | E | L | I | Q | V | A | D | S | L | V | R | H | N | I | D | G |
Query Conservation |   |
  |   |   |   |
|
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|
|
|
| . | . | . | . | . | . |
|
|   |   |   |   |
|
|   |   |
|   |   |   |
|
|
|   |
Template Sequence |   |
. |
. |
. |
F | V | Y | P | F | G | M | P | I | V | Q | R | Y | L | R | G | T | A | E | G | M | S | L | N | N | I | Y | G | A | S | K | Q | K | I | S | P | R | D | I | E | E | I | A | G | H | S | G | L | P | V | F | V | K | . |
. |
. |
. |
. |
. |
G | I | Q | H | P | E | D | A | D | M | A | I | K | R | G | A | S | G |
Template Known Secondary structure |   |
. | . | . |
|
|
| S | S |
|
| T | T | T | G | G | G | T | T | S |
| G | G | G |
|
|  |  |  |  |  |  |  | S |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  | . | . | . | . | . | . |  |  |
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |
Template Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
1189 | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . |
  |
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | A | T | N | T | T | L | D | R | S | L | V | Q | G | M | K | N | C | D | Q | T | G | G | L | S | G | R | P | L | Q | L | K | S | T | E | I | I | R | R | L | S | L | E | L | N | G | R | L | P | I | I | G | V | G | G | I | D | S | V | I | A | A | R | E | K | I | A | A | G | A | S | L | V | Q | I | Y | S | G | F |
Query Conservation |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|   |   |
|   |
|
|   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|
|   |
|
|
|
|
|   |
|   |
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |
Template Sequence |   |
I | W | V | S | N | H | G | A | R | Q | L | Y | E | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | G | S | F | D | T | L | P | A | I | A | E | R | V | N | K | R | V | P | I | V | F | D | S | G | V | R | R | G | E | H | V | A | K | A | L | A | S | G | A | D | V | V | A | L | G | R | P | V |
Template Known Secondary structure |   |
 |  |  |
|
| G | G | G | T | S | S | S | S |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |
| S | S |
|
| S |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . |
  |
  |   |
322 | . | |
|
|
|
. | . | . | . | . | . | 330 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | F | . |
. |
. |
. |
K | G | P | P | L | I | K | E | I | V | T | H | I |
Query Conservation |   |
  |   | . | . | . | . |   |
|
|   |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |   |
|
Template Sequence |   |
L | F | G | L | A | L | G | G | W | Q | G | A | Y | S | V | L | D | Y | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1323 | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . |
  |