|   |
266 | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | H | I | E | Q | L | V | G | E | C | R | V | M | R | Q | L | K | R | L | I | S | R | I | A | P | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | S | V | M | V | V | G | E | S | G | T | G | K | E | V | V | A | R | A | I | H | K | L | S | G | R | R | N | K | P | F | I | A | I | N | C | A | A | I | P | E | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |
Template Sequence |   |
N | V | K | W | S | D | V | A | G | L | E | G | A | K | E | A | L | K | E | A | V | I | L | P | I | K | F | P | H | L | F | T | G | K | R | T | P | W | R | G | I | L | L | F | G | P | P | G | T | G | K | S | Y | L | A | K | A | V | A | T | E | A | . |
. |
N | N | S | T | F | F | S | I | S | S | S | D | L | V | . |
. |
Template Known Secondary structure |   |
|
|
| G | G | G | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | S |
| T | T |
|
|
|
| S |  |  |  |  |  | S | S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T | . | . | T | S |
|  |  |  |  |  |  |
|
| S | S |
| . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |
|
|
|  |  |
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
|
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | E | S | E | L | F | G | Y | V | K | G | A | F | T | G | A | S | A | N | G | K | T | G | L | I | Q | A | A | N | T | G | T | L | F | L | D | E | I | G | D | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | M | L | Q | A | K | L | L | R | A | I | E | A | R | E | I | L | P | I | G | A | S | S | P | I | Q |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
S | K | W | L | G | E | S | E | K | L | V | K | N | L | F | Q | L | A | R | E | N | K | P | S | I | I | F | I | D | E | I | D | S | L | C | G | S | R | S | E | N | E | S | E | A | A | R | R | I | K | T | E | F | L | V | Q | M | Q | . |
. |
. |
. |
. |
. |
. |
. |
G | V | G | V | D | N |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |
| S | S |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |  |  |  |  |  |  | T | T | T | G | G | G |
|
| S | S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |
| S | S | S |
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . |
  |
  |   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | |
. | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | D | I | R | I | I | S | A | T | N | Q | N | L | A | Q | F | I | A | E | G | K | F | R | E | D | L | F | Y | R | L | N | . |
V | I | P | I | T | L | P | P | L | R | E | R | Q | E | D | I | E | L | L | V | H | Y | F | L | H | L | H | T | R | R | L | G | S | V | Y | P | G | I | A | P | D | V | V | E | I | L | R | K |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   | . |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |
|
|
|   | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|   |
|
|
|   |   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
Template Sequence |   |
D | G | I | L | V | L | G | A | T | N | I | . |
. |
. |
. |
. |
. |
. |
P | W | V | L | D | S | A | I | R | R | R | F | E | K | R | I | Y | I | P | L | P | E | P | H | A | R | A | A | M | F | K | L | H | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | T | Q | N | S | L | T | E | A | D | F | R | E | L | G | R |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . | . | T | T | T | S |
|  |  |  |  |  | T |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | T | T |
|
| B |
|
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
  |
  |   |
484 | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | R | W | P | G | N | L | R | E | L | S | N | L | M | E | Y | L | V |
Query Conservation |   |
  |   |
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |
Template Sequence |   |
K | T | D | G | Y | S | G | A | D | I | S | I | I | V | R | D | A | L |
Template Known Secondary structure |   |
T |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
332 | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |