|   |
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | R | D | V | A | G | Q | A | Q | T | G | T | G | K | T | M | A | F | L | T | S | T | F | H | Y | L | L | S | H | P | A | I | A | D | R | K | V | N | Q | P | R | A | L | I | M | A | P | T | R | E | L | A | V | Q | I | H | A | D | A | E | P | L | A | E | A | T | G | L | K | L | G | L | A | Y | G | G | D | G | Y |
Query Conservation |   |
  |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|
|   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|   |   |
|
| . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |
Template Sequence |   |
S | F | Q | V | A | H | L | H | A | P | T | G | S | G | K | S | . |
. |
T | K | V | P | A | A | Y | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | Q | G | Y | K | V | L | V | L | N | P | S | V | A | A | T | L | G | F | G | A | Y | M | S | K | A | H | G | I | D | P | N | I | R | T | G | V | R | T | I | T | T | G |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |
|
| T | T | S |
| T | T | . | . | T |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  | T | T |
|
|  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
| S | S |
|  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1196 | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | |
|
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . |
  |
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | K | Q | L | K | V | L | E | S | G | V | D | I | L | I | G | T | T | G | R | L | I | D | Y | A | K | Q | N | H | I | N | L | G | A | I | Q | V | V | V | L | D | E | A | D | R | M | Y | D | L | G | F | I | K | D | I | R | W | L | F | R | R | M | P | P | A | N | Q | R | L | N | M | L | F | S | A | T | L | S | Y | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|   |
|   |
|
|   | . | . | . |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
| . |
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | P | V | T | Y | S | T | Y | G | K | F | L | A | . |
. |
. |
D | G | G | C | S | G | G | A | Y | D | I | I | I | C | D | E | C | H | S | T | D | S | T | T | I | L | . |
G | I | G | T | V | L | D | Q | A | E | T | A | G | A | R | L | V | V | L | A | T | A | T | P | P | G | S |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  |  |  |  |  |  | . | . | . | T | T | S |
|
| T | T | S |
| S |  |  |  |  | T | T | T | T |
|
| S |  |  |  |  |  | . |  |  |  |  |  |  |  |  | T | T | T | T | T |
| S |  |  |  |  |  |  | S | S |
| T | T |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
1263 | . | . | . | . | . | . | 1270 | . | . | . | . | . | |
|
|
. | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | |
. | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . |
  |
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | E | L | A | F | E | Q | M | N | N | A | E | Y | I | E | V | E | P | E | Q | K | T | G | H | R | I | K | E | E | L | F | Y | P | S | N | E | E | K | M | R | L | L | Q | T | L | I | E | E | E | W | P | D | R | A | I | I | F | A | N | T | K | H | R | C | E | E | I | W | G | H | L | A | A | D | G | H | R | V | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | T | V | P | H | P | N | I | E | E | V | A | L | S | N | T | G | E | I | P | F | Y | G | K | A | I | P | I | E | A | I | R | G | G | R | H | L | I | F | C | H | S | K | K | K | C | D | E | L | A | A | K | L | S | G | L | G | I | N | A | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| T | T |  |  |  |  |  |
|
| S |
| S | S |  |  |  | T | T |  |  |  |
| G | G | G | T | S | S | S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1329 | 1330 | . | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | . | . | 1380 | . | . | . | . | . | . | . | . | . |
  |
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | |
|
|
|
|
|
|
|
. | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 340 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | T | G | D | V | A | Q | K | K | R | L | R | I | L | D | E | F | T | R | G | D | L | D | I | L | V | A | T | D | V | A | A | R | G | L | H | I | P | A | V | T | H | V | F | N | . |
. |
. |
. |
. |
. |
. |
. |
Y | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | D | C | E | D | Y | V | H | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |
|
|
|   |
|   |
|   |   |
|
|   | . | . | . | . | . | . | . | . |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
Template Sequence |   |
A | Y | Y | R | G | L | D | V | S | V | I | . |
. |
. |
. |
. |
. |
. |
P | T | I | G | D | V | V | V | V | A | T | D | A | L | M | T | G | Y | T | G | . |
D | F | D | S | V | I | D | C | N | T | C | V | T | Q | T | V | D | F | S | L | D | P | T | F | T | I | E | T | T | T | V | P | Q | D | A | V | S | R | S | Q | R |
Template Known Secondary structure |   |
 |  |
| T | T | S |
| G | G | G | S | . | . | . | . | . | . | . |
| S | S | S | S |  |  |  |  |  |
| T | T |  |  |  |  |
|
|
| . |
|
| S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |
| B |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |
| . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1390 | . | . | . | . | . | . | . | . | . | 1400 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 1410 | . | . | . | . | . | . | . | . | . | 1420 | |
. | . | . | . | . | . | . | . | . | 1430 | . | . | . | . | . | . | . | . | . | 1440 | . | . | . | . | . | . | . | . | . | 1450 | . | . | . | . | . | . | . | . | . | 1460 | . |
  |
  |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | R | T | G | R | A | G | A | S | G | H | S | I | S | L | A | C | E | E |
Query Conservation |   |
  |
|
|   |
|
|   |
|   |   |
|   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
| . |   |   |
|
|   |
|
|   |
|   |   |   |   |
Template Sequence |   |
R | G | R | T | G | R | . |
G | R | R | G | I | Y | R | F | V | T | P | G | E |
Template Known Secondary structure |   |
 | T | T | S |
| S | . | S | S |
|  |  |  |  |  | S |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1462 | . | . | . | . | . | |
. | . | 1470 | . | . | . | . | . | . | . | . | . | 1480 |
  |