|   |
39 | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | A | T | Q | V | E | F | T | D | P | E | I | V | A | E | Y | I | T | Y | P | S | P | N | G | H | G | E | V | R | G | Y | L | V | K | P | A | K | M | S | G | K | T | P | A | V | V | V | V | H | E | N | R | G | L | . |
. |
. |
. |
. |
N | P | Y | I | E | D | V | A | R | R | V | A | K | A | G | Y | I | A | L | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   | . |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|
|
Template Sequence |   |
S | I | A | L | D | L | P | T | D | R | D | D | V | E | T | S | T | E | T | I | L | G | V | D | G | N | . |
E | I | T | L | H | V | F | R | P | A | G | V | E | G | V | L | P | G | L | V | Y | T | H | G | G | G | M | T | I | L | T | T | D | N | R | V | H | R | R | W | C | T | D | L | A | A | A | G | S | V | V | V | M |
Template Known Secondary structure |   |
 | S |
|
|
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |
| T | T | S |
| . |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |  |  |  |  |
|
| S | T | T | T | S | S |
| S | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
77 | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
114 | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
|
|
|
|
|
. | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
P | D | G | L | S | S | V | G | G | Y | P | G | N | D | D | K | G | R | E | L | Q | Q | Q | V | D | P | T | N | L | M | N | D | F | F | A | A | I | E | F | M | Q | R | Y | P | Q | A | T | G | . |
. |
K | V | G | I | T | G | F | C | Y | G | G | G | V | S | N | A | A | A | V | A | . |
. |
. |
. |
. |
. |
Y | P | E | L |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |
|   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | D | F | R | N | A | W | T | A | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | H | H | P | F | P | S | G | V | E | D | C | L | A | A | V | L | W | V | D | E | H | R | E | S | L | G | L | S | G | V | V | V | Q | G | E | S | G | G | G | N | L | A | I | A | T | T | L | L | A | K | R | R | G | R | L | D | A | I |
Template Known Secondary structure |   |
 |  |
|
|
| S |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
  |
  |   |
186 | . | . | . | 190 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | C | A | V | P | F | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | Q | A | P | T | A | D | V | A | K | I | E | A | P | L | L | L | H | F |
Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
Template Sequence |   |
D | G | V | Y | A | S | I | P | Y | I | S | G | G | Y | A | W | D | H | E | R | R | L | T | E | L | P | S | L | V | E | N | D | G | Y | F | I | E | N | G | G | M | A | L | L | V | R | A | Y | D | P | T | G | E | H | A | E | D | P | I | A | W | P | Y | F | A | S | E | D | E | L | R | G | L | P | P | F | V | V | A | V |
Template Known Secondary structure |   |
S |  |  |  |  |  | S |
|
|
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |
| T |  |  |  |  | T | T | T | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | S | S | S | S | T | T | T | T |
| T | T | T |
| G | G | G |
|
|  |  |  |  | T | T |
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . |
  |
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | L | D | T | R | I | N | E | G | W | P | A | Y | E | A | A | L | K | A | N | N | K | V | Y | E | A | Y | I | Y | P | G | V | N | H | G | F | H | N | D | S | T | P | R | Y | D | K | S | A | A | D | L | A | W | Q | R | T | L | K | W | F | D | K | Y |
Query Conservation |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
| . |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |
|   |   |
|   |   |
|
|
|   |   |   |   |   |   | . |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
N | E | L | D | . |
P | L | R | D | E | G | I | A | F | A | R | R | L | A | R | A | G | V | D | V | A | A | R | V | N | I | G | L | V | H | G | A | D | V | I | F | R | H | . |
W | L | P | A | A | L | E | S | T | V | R | D | V | A | G | F | A | A | D | R |
Template Known Secondary structure |   |
 | T | T |
| . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  | T | T |
|
| T | T |  |  |  |  | S | G | G | . | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
305 | . | . | . | |
. | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
. | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
  |