Job Description P42593 Confidence 99.75% Date Thu Jan 5 12:01:40 GMT 2012 Rank 116 Aligned Residues 261 % Identity 14% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		9	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.		.	.	.	.	.	70	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																										.															.	.	.	.	.	.	.	.	.
Query SS confidence																																																										.															.	.	.	.	.	.	.	.	.
Query Sequence		P	L	D	L	G	F	T	T	L	K	N	R	V	L	M	G	S	M	H	T	G	L	E	E	Y	P	D	G	A	E	R	L	A	A	F	Y	A	E	R	A	R	H	G	V	A	L	I	V	S	G	G	I	A	P	D	L	.	T	G	V	G	M	E	G	G	A	M	L	N	D	A	.	.	.	.	.	.	.	.	.
Query Conservation																																																										.															.	.	.	.	.	.	.	.	.
Alig confidence																			.	.	.									.	.	.	.	.	.	.																						.															.	.	.	.	.	.	.	.	.
Template Conservation																			.	.	.									.	.	.	.	.	.	.
Template Sequence		E	V	R	V	L	G	H	K	F	R	N	P	V	G	I	A	A	.	.	.	G	F	D	K	H	G	E	A	.	.	.	.	.	.	.	V	D	G	L	Y	K	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	Q	E	G	N	P	R	P	R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F
Template Known Secondary structure						T	T				S	S	S					T	.	.	.	T	T	T	T	T	S	S		.	.	.	.	.	.	.							T	T		S									S	S		B			S		S							G	G	G	T
Template Predicted Secondary structure																			.	.	.									.	.	.	.	.	.	.
Template SS confidence
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.				.	.	.	100	.	.	.	.								.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
											79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	S	Q	I	P	H	H	R	T	I	T	E	A	V	H	Q	E	G	G	K	I	A	L	Q	I	L	H	T	G	R	Y	S	Y	Q	P	H	L	V	A	P	S	A	L	Q	A	P	I	N	R	F	V	P	H	E	L	S	H	E	E	I	L	Q	L	I	D	N	F	A	R	C	A	Q
Query Conservation		.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		N	S	H	G	L	S	V	V	E	H	R	L	R	A	R	Q	Q	K	Q	A	K	L	T	E	D	G	L	P	L	G	V	N	L	G	K	N	K	T	S	V	D	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	A	E	D	Y	A	E	G	V	R
Template Known Secondary structure			B												T	T										T	T											T	T		S		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190																														.	.	.	.	.	.	.	.	.	200
		150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.		.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
Predicted Secondary structure																														.
Query SS confidence																														.
Query Sequence		L	A	R	E	A	G	Y	D	G	V	E	V	M	G	S	E	G	Y	L	I	N	E	F	L	T	L	R	T	.	N	Q	R	S	D	Q	W	G	G	D	Y	R	N	R	M	R	F	A	V	E	V	V	R	A	V	R	E	R	V	G	N	D	F	I	I	I	Y	R	L	S	M	L	D	L	V	E	D	G	G	T	F
Query Conservation																														.
Alig confidence						.											.	.	.	.	.	.	.	.	.					.																														.	.												.	.	.	.	.	.
Template Conservation						.											.	.	.	.	.	.	.	.	.																																			.	.												.	.	.	.	.	.
Template Sequence		V	L	G	P	.	L	A	D	Y	L	V	V	N	V	S	.	.	.	.	.	.	.	.	.	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K	V	L	Q	E	R	D	G	L	R	R	V	H	.	.	R	P	A	V	L	V	K	I	A	P	D	.	.	.	.	.	.	L	T	S
Template Known Secondary structure				G	G	.	G		S								.	.	.	.	.	.	.	.	.		T	T	S	T	T	S	G	G	G	G	S																	T	S		G	G	G	.	.										S		.	.	.	.	.	.
Template Predicted Secondary structure						.											.	.	.	.	.	.	.	.	.																																			.	.												.	.	.	.	.	.
Template SS confidence
		201	.	.	.		.	.	.	.	.	210	.	.	.	.										.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.			.	250	.	.	.	.	.	.	.	.	.							260	.	.
		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.											.	270	.	.	.	.	.	.	.	.	.	280	.			.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure																																										.	.	.	.	.	.	.	.	.	.														.	.
Query SS confidence																																										.	.	.	.	.	.	.	.	.	.														.	.
Query Sequence		A	E	T	V	E	L	A	Q	A	I	E	A	A	G	A	T	I	I	N	T	G	I	G	W	H	E	A	R	I	P	T	I	A	T	P	V	P	R	G	A	.	.	.	.	.	.	.	.	.	.	F	S	W	V	T	R	K	L	K	G	H	V	S	.	.	L	P	L	V	T	T	N	R	I	N	D	P	Q	V	A
Query Conservation																																										.	.	.	.	.	.	.	.	.	.														.	.
Alig confidence																																										.	.	.	.	.	.	.	.	.	.														.	.
Template Conservation
Template Sequence		Q	D	K	E	D	I	A	S	V	V	K	E	L	G	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A	G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S	T	Q	T	I	R	E	M	Y	A	L	T	Q	G	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A
Template Known Secondary structure															T										B	S				T	T				T	T	T	T	S	S	S																						T	T	T		S						S	S			S
Template Predicted Secondary structure
Template SS confidence
		263	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.		.	.	.	.	320	.	.	.	.	.	.	.
Predicted Secondary structure																					.
Query SS confidence																					.
Query Sequence		D	D	I	L	S	R	G	D	A	D	M	V	S	M	A	R	P	F	L	.	A	D	A	E	L	L	S	K	A	Q	S	G
Query Conservation																					.
Alig confidence									.												.
Template Conservation									.
Template Sequence		L	E	K	I	R	A	G	.	A	S	L	V	Q	L	Y	T	A	L	T	F	W	G	P	P	V	V	G	K	V	K	R	E
Template Known Secondary structure								T	.		S					S								T
Template Predicted Secondary structure									.
Template SS confidence
		343	.	.	.	.	.	.		350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions