|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | |
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
. | . | . | . | . | . | . | |
|
|
|
|
|
|
70 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
E | L | L | L | L | S | N | S | T | L | P | G | K | A | W | L | E | H | A | L | P | L | I | A | E | Q | L | Q | G | R | . |
R | S | A | V | F | I | P | F | A | G | V | T | Q | T | W | D | D | Y | T | A | K | T | A | A | V | L | A | P | L | G | V | . |
S | V | T | G | I | H | S | . |
. |
. |
. |
. |
. |
. |
V | V | D |
Query Conservation |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   | . |   |
|   |   |
|   |   | . | . | . | . | . | . | . |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |
|   |   |
|
|
|
|   |
|   |   |   | . | . |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|
|   |
|
|   |
|
|
| . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
A | I | L | I | I | G | G | A | E | D | K | V | H | . |
. |
G | R | E | I | L | Q | T | F | W | S | R | S | G | G | N | D | A | I | I | G | I | I | P | S | A | S | . |
. |
R | E | P | L | L | I | G | E | R | Y | Q | T | I | F | S | D | M | G | V | K | E | L | K | V | L | D | I | R | D | R | A | Q | G | D | D | S | G |
Template Known Secondary structure |   |
|  |  |  |  |
| S | S |
|
| S | S | S | . | . |
|
|  |  |  |  |  |  |  |  |  | T | T | G | G | G |
|  |  |  |  |  |
| T | T |
| . | . | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
|
|
| S | G | G | G | G | G |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | |
|
. | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
. | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | A | A | I | E | N | A | E | I | V | I | V | G | G | G | N | T | F | Q | L | L | K | Q | C | R | E | R | G | L | L | A | P | I | T | D | V | V | K | R | G | . |
A | L | Y | I | G | W | S | A | G | A | N | L | A | C | P | T | I | . |
. |
. |
. |
R | T | T | N | D | M | P | I | V | D | P | Q | G | F | D | A | L |
Query Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
| . |   |   |   |   |
|   |
|
|
|
|   |
|   |   |   |   |
| . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
Y | R | L | F | V | E | Q | C | T | G | I | F | M | T | G | G | D | Q | L | R | L | C | G | L | L | A | D | T | P | L | M | D | R | I | R | Q | R | V | H | N | G | E | I | S | L | A | G | T | S | A | G | A | A | V | M | G | H | H | M | I | A | G | G | S | S | G | E | W | P | N | R | A | L | V | D | M | A | V | G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  |  | T |  |  |  |  | T | T | S | S |  |  |  |  |  |  |
|
| S | S |
|
|
| G | G | G |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
148 | . | 150 | . | |
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | |
|
|
Predicted Secondary structure |   |
|
|
|
| . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  | . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . |
Query SS confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
N | L | F | P | . |
L | Q | I | N | P | H | F | T | N | A | L | P | E | G | H | K | G | E | T | R | E | Q | R | I | R | E | L | L | V | V | A | P | E | L | T | I | I | G | L | P | E | G | N | W | I | T | V | S | . |
K | G | H | A | T | L | G | G | P | N | T | T | Y | V | F | K | A | G | E | E | A | V | P | . |
. |
. |
Query Conservation |   |
|
|   |   | . |   |   |
|   |
|
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|   |
|   | . |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   | . | . | . |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|
|
|   |   |   |
|
|
|   |
|
|   |   | . | . | . | . | . | . | . | . |
|   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | I | V | P | E | I | V | V | D | Q | H | F | H | N | . |
. |
. |
. |
. |
. |
. |
. |
R | N | R | M | A | R | L | L | S | A | I | S | T | H | P | E | L | L | G | L | G | I | D | E | D | T | C | A | M | F | E | R | D | G | S | V | K | V | I | G | Q | G | T | V | S | F | V | D | A | R | D | M | S | Y | T | N | A | A |
Template Known Secondary structure |   |
| S | S | T | T |  |  |  |  |
| S | T | T | T | . | . | . | . | . | . | . | . | T | T | T |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
| T | T |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  | S | S |
|  |  |  |  |  |
| T | T |
|
|  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
|
223 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
Query Sequence |   |
. |
L | E | A | G | H | R | F |
Query Conservation |   |
. |
|   |   |
|   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|
|
Template Sequence |   |
L | V | G | A | N | A | P | L |
Template Known Secondary structure |   |
T | S |
| T | T | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . |
  |