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Job DescriptionP0A9W3
Confidence100.00%DateThu Jan 5 11:11:33 GMT 2012
Rank6Aligned Residues464
% Identity28%Templatec2ygrD_
PDB info PDB header:hydrolaseChain: D: PDB Molecule:uvrabc system protein a; PDBTitle: mycobacterium tuberculosis uvra
Resolution3.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   22.......30.........40......... 50.........60.........70.........80
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Query Sequence  LKNISLSFFPGAKIGVLGLNGAGKSTLL. . . . . . . . . . . . . . . . . . . . . RIMAGIDKDIEGEARPQPDIKIGYLPQEPQL
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Template Sequence  LRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLSPAVS. . IDQKSTN
Template Known Secondary structure 

SSSS
STTSSTTTTTT
STTTS




SS


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S



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   15....20.........30.........40.........50.........60.........70.........80..... ....90..
 
   81. .......90.........100
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Query Sequence  NP. . . . . . . EHTVRESIEEAVSEVVNA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation    .......  

   
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Template Sequence  RNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPVVRTRKGEFADLFDKLNA
Template Known Secondary structure 

TT
BTTSSB
B
TTT

B
B


SS

SS


SSSSB
S
TT
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   93......100.........110.........120.........130.........140.........150.........160.........170..
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation   
     
      
     
          
    
       
                                   
Template Sequence  QGYSRVRVDGVVHPLTDPPRARRQEKHDIEVVVDKRRLTDSVETALNLADGIVVLEFVDHRFSEKLACPNGHALAVDDLE
Template Known Secondary structure  S

S
BSSS
B
TTS




TTS
B




SSS







TTBB
TT



S
S


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   173......180.........190.........200.........210.........220.........230.........240.........250..
 
   101........110....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LKRLDEVYALYADP. . . . . . . . . . .
Query Conservation  .......................................................              ...........
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Template Conservation     

 

  
 
  
 
 
     
    
     
   

                              
       
Template Sequence  PRSFSFNSPYGACPDCSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLGEALGFDVDTPPAKARKA
Template Known Secondary structure  GGGG
TTSTTTBBTTBSSS


SS

SSSSS
S
STT
SSTTS

SS


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   270.........280.........290.........300.........310.........320.........330.........340.........
 
   115..
Predicted Secondary structure  .............................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DAD
Query Conservation  .............................................................................   
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Template Conservation 

 
                          
  
               
        
  
 
 

   

      
 
Template Sequence  ILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCAGTRLKPEILAVTLKSIA
Template Known Secondary structure  T


S





SSS









S
TTTT
TTTTTS
B
T
B

GGG
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   354.....360.........370.........380.........390.........400.........410.........420.........430...
 
   118.120.........130.........140.........150 ..... ....160.........170.........180.. .
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Query Sequence  FDKLAAEQGRLEEIIQAHDGHNLNVQLERAADA. . . . . . . . . . LRLPD. . WDAKIANLSGGERRRVALCRLLLEKPD. . M
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Template Sequence  EVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLSLSRAAATLSGGEAQRIRLATQIGSGLVGVL
Template Known Secondary structure 


TT

TTSTT
TTS
TTSBGGG

TT


S
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   444.....450.........460.........470.........480.........490.........500.........510.........520...
 
   184.....190.........200........ .210.........220.........230.. .......240.........250....
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Query Sequence  LLLDEPTNHLDAESVAWLERFLHDF. . . EGTVVAITHDRYFLDNVAGWILEL. . . . . . DRGEGIPWEGNYSSWLEQKDQR
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Template Sequence  YVLDEPSIGLHQRDNRRLIETLTRLRDLGNTLIVVEHDEDTIE. HADWIVDIGPGAGEHGGRIVH. SGPYDELLRNKDSI
Template Known Secondary structure 
TTTT


B

.T
SSSSSGGG

S.

SS
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   524.....530.........540.........550.........560...... ...570.........580....... ..590.........600.
 
   255....260.........270.........280.........290.........300.........310.........320.........330....
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Query Sequence  LAQEASQEAARRKSIEKELEWVRQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
Query Conservation                                      
                                
        
 
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Template Conservation      ............................................
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Template Sequence  TGAY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LSGRESIEIPAIRRSVDPRRQLTVVGAREH. .
Template Known Secondary structure  ............................................TS





SS




TTS
ST..
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   602... ....610.........620.........630.....
 
   335....340.........350.........360....... ..370.........380...... ...390.........400..
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Query Sequence  DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFR. . MISGQEQPDSGTITLGETV. . . . . . . . . . KLASVDQFRDSMDNSK
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Template Sequence  . . . NLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDYLDKLVRIDQSPIGRTPRS
Template Known Secondary structure  ...T

SSSSSTTSSTTS






SS


GGG




S
S
SSTT
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   636...640.........650.........660.........670.........680.........690.........700.........710..
 
   403......410.
Predicted Secondary structure 
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Query Sequence  TVWEEVSGG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 

   
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Template Sequence  NPATYTGVFDKIRTLFAATNEAKVRGYKPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCEVCQGARYNRETLEVH
Template Known Secondary structure  STTSTTT

GGGS
TTSTTTB
SSSTTSS

SSS


TTTTS
SB
T

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   713......720.........730.........740.........750.........760.........770.........780.........790..
 
   412.......420.........430.........440.........450.........460.. .......470.
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Query Sequence  . . . . . . . . . . . . . . . . . LDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGERGRLHLAKLLQVG. . . GNMLLLDEP
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Template Sequence  YKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASELQKRSTGRTVYILDEP
Template Known Secondary structure  BTTB
TSBSTT
SS
SSSBTT

GGGS
SSS


SS
SS
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   793......800.........810.........820.........830.........840.........850.........860.........870..
 
   472.......480.........490 .........500.........510..... ....520.........530.. .......
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Query Sequence  TNDLDIETLRALENALLEF. . . PGCAMVISHDRWFLDRIATHILDYQ. . . . . DEGKVEFFEGNFTEYEE. . . . YKKRTLG
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Template Sequence  TTGLHFDDIRKLLNVINGLVDKGNTVIVIEHNLDVIKT. SDWIIDLGPEGGAGGGTVV. AQGTPEDVAAVPASYTGKFLA
Template Known Secondary structure  STT

T



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SSSSTTS
S.
S
TT
SS
T
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   873......880.........890.........900.........910 .........920......... 930.........940.........950
 
   540
Predicted Secondary structure 
Query SS confidence 
Query Sequence  A
Query Conservation   
Alig confidence 
Template Conservation   
Template Sequence  E
Template Known Secondary structure  T
Template Predicted Secondary structure 
Template SS confidence 
   951
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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