|   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | V | N | D | G | S | E | P | V | P | E | G | R | G | E | L | D | V | N | I | H | Q | F | T | Y | P | Q | T | D | H | P | A | L | E | N | V | N | F | A | L | K | P | G | Q | M | L | G | I | C | G | P | T | G | S | G | K | S | T | L | L | S | L | I | Q | . |
. |
. |
. |
. |
R | H | F | D | V | S | E | G | D | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|
|   |   |
|
|
|   |
|   |   |
|   |   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|   | . | . | . | . | . |
|   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | R | H | T | E | P | H | T | P | R | E | P | A | G | W | L | E | L | N | G | V | T | . |
. |
. |
. |
. |
. |
. |
R | N | N | L | D | N | L | D | V | R | F | P | L | G | V | M | T | S | V | T | G | V | S | G | S | G | K | S | T | L | V | S | Q | A | L | V | D | A | L | A | A | H | F | G | Q | G | S | A | R | L |
Template Known Secondary structure |   |
T |
|
|
|
|
|
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  | T | T |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  | S | T | T | S | S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . |
  |
  |   |
394 | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
R | F | H | D | I | P | L | T | K | L | Q | L | D | S | W | R | S | R | L | A | V | V | S | Q | T | P | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |
Template Sequence |   |
G | G | D | L | A | Q | I | T | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | R | V | D | Q | K | P | I | G | R | T | P | R | S | N | M | A | T | Y | T | G | L | F | D | Q | V | R | K | L | F | A | A | T | P | L | A | K | K | R | G | Y | N | A | G | R | F | S | F | N | V | K | G | G | R | C | E | H | C | Q | G | E |
Template Known Secondary structure |   |
| S | S | G | G | G |
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |
| S | S |
| S |
| S | S | T | T |
|
|  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T | S | S | T |  |  |  |  | S |
|
|
| T | T | S | S |
| S | S | S | S | S | S | B |
| S | S | S | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
577 | . | . | 580 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
421 | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | F | S | D | T | V | A | N | N | I | A | L | G | C | P | N | A | T | Q | Q | E | I | E | H | V | A | R | L | A | S | V | H | D | D | I | L | R | L | P | Q | G | Y | D | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
G | W | V | M | V | P | S | V | Y | A | P | C | P | V | C | H | G | T | R | Y | N | A | E | T | L | E | V | E | Y | R | G | K | N | I | A | D | V | L | A | L | T | V | D | E | A | H | D | F | F | A | D | E | S | A | I | F | R | A | L | D | T | L | R | E | V | G | L | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | L |
Template Known Secondary structure |   |
|  |  |  |
|
|
|
|  |  |  |
| T | T | T | S | S | S |
| B |
| T | T | G | G | G |
|
| S | S | S |
|
|  |  |  |  |  | T |
| B |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | . | . | . | . | . | . | . | . | . | . | T | S |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
648 | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . |
  |
  |   |
465 | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | |
|
|
. | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | V | G | E | R | G | V | M | L | S | G | G | Q | K | Q | R | I | S | I | A | R | A | L | L | V | N | A | E | . |
. |
. |
I | L | I | L | D | D | A | L | S | A | V | D | G | R | T | E | H | Q | I | L | H | N | L | R | Q | W | G | . |
Q | G | R | T | V | I | I | S | A | H | R | L | S | A | L | T | E | A | S | E | I |
Query Conservation |   |
  |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   | . | . | . |
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|
|   |
|
Template Sequence |   |
R | L | G | Q | P | A | T | E | L | S | G | G | E | A | Q | R | I | K | L | A | T | E | L | R | R | S | G | R | G | G | T | V | Y | V | L | D | E | P | T | T | G | L | H | P | A | D | V | E | R | L | Q | R | Q | L | V | K | L | V | D | A | G | N | T | V | I | A | V | E | H | K | M | Q | V | V | A | A | S | D | W | V |
Template Known Secondary structure |   |
B | T | T |
|
| G | G | G |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |  |
| S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
|  |  |  |  | T | T |
| S |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
723 | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . |
  |
  |   |
541 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | |
. | . | . | . | . | . | . | . | 570 |
Predicted Secondary structure |   |
 |  |  | . | . | . | . | . | . |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | V | M | . |
. |
. |
. |
. |
. |
Q | H | G | H | I | A | Q | R | G | N | H | D | V | L | A | Q | Q | S | . |
G | W | Y | R | D | M | Y | R | Y |
Query Conservation |   |
  |   |
| . | . | . | . | . | . |   |   |
|   |
|   |   |   |
|
|   |   |
|
|   |   |   |   | . |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |
Template Sequence |   |
L | D | I | G | P | G | A | G | E | D | G | G | R | L | V | A | Q | G | T | P | A | E | V | A | Q | A | A | G | S | V | T | A | P | Y | L | R | A |
Template Known Secondary structure |   |
 |  |  |
| S | S | S | G | G | G |
|
| S |  |  |  |  |  | S |  |  |  |  |  | T |
| S | S |
| S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
803 | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . |
  |