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Job DescriptionP77334
Confidence42.00%DateThu Jan 5 12:27:56 GMT 2012
Rank451Aligned Residues188
% Identity16%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   471........480.........490.........500.........510.........520.........530.. ......
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Query Sequence  LGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQTIFTALKQVLQELNFEYCPIDVELT. . . . . . . . . . . . ESCLIE
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Template Sequence  LSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGP. LADYLVVNVSSPNTAGLRSLQGKAELRR
Template Known Secondary structure  TTTT




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   154.....160.........170.........180.........190.........200.... .....210.........220.........230..
 
   539540.........550... ......560........ .570.........580...... ...590.......
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Query Sequence  NDELALSVIQQFSQL. GAQVHLDDFGTGYSS. . . . . . LSQLARFPIDAIKLDQVF. . . . . . . . . . . . . . VRDIHKQPVSQ
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Template Sequence  LLTKVLQERDGLRRVHRPAVLVK. IAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRD
Template Known Secondary structure  TS
GGG

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BS


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   233......240.........250..... ....260.........270.........280.........290.........300.........310.
 
   598.600.........610. ....... .620.........630....... ..640.........650.........660
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Query Sequence  SLVRAIVAVAQALN. . LQVIAEG. VESAKEDAFLTKNGINERQ. . . GFLFAKPMPAVAFERWYKRYLKR
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Template Sequence  LSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKE
Template Known Secondary structure  TTT
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ST
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   312.......320.........330.........340.........350.........360.........370.........380
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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