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Job DescriptionP77541
Confidence84.12%DateThu Jan 5 12:30:23 GMT 2012
Rank378Aligned Residues199
% Identity14%Templatec2fptA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors
Resolution2.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   53......60........ .70.........80...... ...90.........100.........110.........120........
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Query Sequence  SLGLPDLGISTLDDVL. . . TDIRRITDVCSLPLLVDA. DIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPN
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Template Sequence  RYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQ
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B

TTTT




TT
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TTSTTSGGGG
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   146...150.........160.........170.........180.........190.........200.........210.........220.....
 
   129130.........140.........150.........160.........170.........180.........
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Query Sequence  KAIVSKEEMVDRIRAAVDAKTDPDFVIMARTDALAVEGLDAAIERAQAYVEAGAEMLFPEA. . . . . . . . . . . . . . . . . . .
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Template Sequence  GKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTS. . QDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGG
Template Known Secondary structure  STS
GGG


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   226...230.........240.........250.........260.. .......270.........280.........290.........300...
 
   190.........200.... .....210.........220.........230.........240.........250......
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Query Sequence  . . . . . . . ITELAMYRQFADAVQ. . VPILANITEFGATPLFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQ
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Template Sequence  LSGKPLRDLSTQTIREMYALTQGRVPIIGV. . . GGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEA
Template Known Secondary structure  TTT
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ST
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   304.....310.........320.........330... ......340.........350.........360.........370......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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