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Job DescriptionP07118
Confidence100.00%DateThu Jan 5 11:00:14 GMT 2012
Rank2Aligned Residues788
% Identity22%Templatec1qu2A_
PDB info PDB header:ligase/rnaChain: A: PDB Molecule:isoleucyl-trna synthetase; PDBTitle: insights into editing from an ile-trna synthetase structure2 with trna(ile) and mupirocin
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20...... ...30.........40.........50.........60.........70.........
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Query Sequence  EKTYNPQDIEQPLYEHWEKQGYFKP. . NGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGT
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Template Sequence  PMRGGLPNKEPQIQEKWDAEDQYHKALEKNKGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGW
Template Known Secondary structure 
SS

TTTTTS
B





BSSS


TTT
B




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   15....20.........30.........40.........50.........60.........70.........80.........90....
 
   80.........90.........100.........110.........120.........130.........140.........150.........
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Query Sequence  DHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVR
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Template Sequence  DTHGLPIEQALTKK. . . . . GVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGDFNDPYITLKPEYEAAQIRIFGE
Template Known Secondary structure  B

S.....T

STTT
TTT

S
TTS
TTS
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   95....100........ .110.........120.........130.........140.........150.........160.........
 
   160.........170.........180.........190.........200.........210.........220.........230.........
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Query Sequence  LYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPED
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Template Sequence  MADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFNVKDDKGVVDADAKFIIWTTTPWTIPSNVAITVHPEL
Template Known Secondary structure  TT
TTTT

GGG

B


SSTTGGGTT

B

S
GGGSS

B




TT
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   170.........180.........190.........200.........210.........220.........230.........240.........
 
   240. ........250.........260.........270.........280.
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Query Sequence  PR. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPA
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Template Conservation   
          
                           
  
 
     
       
     
    


 

 

 
Template Sequence  KYGQYNVNGEKYIIAEALSDAVAEALDWDKASIKLEKEYTGKELEWVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPG
Template Known Secondary structure 





TTTT




TTTT

SS








TTT
TT


B

TT

SB





SS

SSS
S


B
TT
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   250.........260.........270.........280.........290.........300.........310.........320.........
 
   282.......290.........300.........310.........320.........330.........340.........350.........360.
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Query Sequence  HDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHD
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Template Sequence  HGEDDYIVGQQYELPVISPIDDKGVFTEEG. . . . . . . . . . . . . . . . . . GQFEGMFYDKANKAVTDLLTEKGALLKLDFIT
Template Known Secondary structure  S
STTTSSS







SSS


TT
..................SS
SSS
SSTTGGGSS



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   330.........340.........350......... 360.........370.........380.........390.
 
   362.......370.........380.........390.........400.........410.........420.........430.........440.
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Query Sequence  LTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDE
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Template Sequence  HSYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIE. . NTNFKVNWGKTRIYNMVRDRGEWVISRQRVWGVPLPVFYAE
Template Known Secondary structure  TTT

B

..TSSS



S
SSS
B



T
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   392.......400.........410.........420........ .430.........440.........450.........460.........
 
   442.......450...... ...460.........470.........480.........490.......
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Query Sequence  AGNVYVGRNEDEVRK. . . . . . . . . . . . . . . . . . . . . . . . ENNLGADVVLRQDEDVLDTWFSSALWTFSTLGWPENTDALR
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Template Sequence  NGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGFTHPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPE. . . . .
Template Known Secondary structure  TS



TS
SSTT


SS
TTS





TTTTTSTT.....
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   470.........480.........490.........500.........510.........520.........530.........540....
 
   498.500.........510.........520.........530.........540.........550.........560.........570.......
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Query Sequence  QFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPEL
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Template Sequence  LSFPADMYLEGSDQYRGWFNSSITTSVATRG. . . . . . VSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQV. . . . . . . . .
Template Known Secondary structure 

SSBSGGGGTTS......S
SBS


TTS



SSSS



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   545....550.........560.........570..... ....580.........590.........600.........
 
   578.580.........590.........600.........610.........620.........630.........640.........650.......
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Query Sequence  LEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTE
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . VKQKGADIARLWVS. STDYLADVRISDEILKQTSDDYRKIRNTLRFMLGNIN
Template Known Secondary structure  ............................T
.TS
TTS


TST
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   610.........620... ......630.........640.........650.........660
 
   658.660... ......670.........680.........690.........700.........710.........720....... ..730....
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Query Sequence  GQDCGF. NGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGG. . TEAELRG
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Template Sequence  DFNPDTDSIPESELLEVDRYLLNRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRS
Template Known Secondary structure  T




GGGS
TT






TTS
TT
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   661........670.........680.........690.........700.........710.........720.........730.........740
 
   735....740.........750.........760.........770.........780...... ...790.........800.........810..
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Query Sequence  TRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDA. . SQVDEAALADTEWLKQAIVAVRNIRA
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Template Sequence  MQTVLYQILVDMTKLLAPILVHTAEEVWSHTP. . . HVKEESVHLADMPKVVEVDQALLDKWRTFMNLRDDVNRALETARN
Template Known Secondary structure  TTTSTTST...T
SSSSGGGS








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   741........750.........760.........770.. .......780.........790.........800.........810.......
 
   813......820.........830.........840.........850.........860......
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Query Sequence  EMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSV
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Template Conservation     
       
 
                 
     

 
             
Template Sequence  EKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVSQVKVVDKLDDQATAY
Template Known Secondary structure  TTS
SSGGG

SS

GGG
S
TTSS
S


TTS
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   818.820.........830.........840.........850.........860.........870.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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