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Job DescriptionP07118
Confidence100.00%DateThu Jan 5 11:00:14 GMT 2012
Rank6Aligned Residues644
% Identity25%Templatec1obhA_
PDB info PDB header:synthetaseChain: A: PDB Molecule:leucyl-trna synthetase; PDBTitle: leucyl-trna synthetase from thermus thermophilus complexed2 with a pre-transfer editing substrate analogue in both3 synthetic active site and editing site
Resolution2.2 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   3......10.........20.........30.........40.........50.........60.........70.........80..
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Query Sequence  KTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHA
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Template Sequence  EKYNPHAIEAKWQRFWEEKGFMKAKDLPGGGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWDAF
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TTTTT


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SS
BT




B


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   2.......10.........20.........30.........40.........50.........60.........70.........80.
 
   83......90.........100.........110.........120.........130.........140.........150.........160..
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Query Sequence  GIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYK
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Template Sequence  GLPAENAALK. . . . . . . . . . . . . . . . . FGVHPKDWTYANIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWE
Template Known Secondary structure  S.................


TT



GGG

BTTS
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   83......90.. .......100.........110.........120.........130.........140.....
 
   163......170.........180.........190..... ....200.........210.........220.........
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Query Sequence  EDLIYRGKRLVNWDPKLRTAISDLEVENRESKG. . . . . . . . . . . . . SMWHIRYPLADGAKTADGKDYLVVATTRPETLLG
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Template Sequence  KGLAYRAKEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEG. . . . . . KEVRIPVFTTRPDTLFG
Template Known Secondary structure  TT



GGGGTTTT

S

BTT......
S
S
GGGGGG
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   146...150.........160.........170.........180.........190.........200.. .......210.........
 
   230.........240.. .......250.........260.........270....
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Query Sequence  DTGVAVNPEDPRY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KDLIGKYVILPLVNRRIPIVGDEHADMEKGTG
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Template Sequence  ATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAYALNPATGERIPIWTADYVLFGYGTG
Template Known Secondary structure 


TT
TTTTTS

GGGTS
S
TTS



TTT

TTS
SSSTTS
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   256...260.........270.........280.........290.........300.........310.........320.........330.....
 
   275....280.........290.........300.........310.........320.........330.........340.........350....
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Query Sequence  CVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLL
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Template Sequence  AIMAVPAHDQRDYEFARKFGLPIKKVIERPGEPLPEPLERAYEE. . . . PGIMVNSGPFDGTESEEGKRKVIAWLEEKGLG
Template Known Secondary structure 
GGG
T





BTTB


SS
SS


S....


SSGGGTT
BTS
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   336...340.........350.........360.........370......... 380.........390.........400.........410.
 
   355....360.........370.........380.........390.........400.........410.........420.........430....
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Query Sequence  EEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHR
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Template Conservation        .......................................................... 
 

 




 

 
Template Sequence  KGRVTY. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RLRDWLISRQRYWGTP
Template Known Secondary structure  ..........................................................S





SSS
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   412..... ..420.........430...
 
   435....440. ........450.........460.........470.........480......... 490........
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Query Sequence  IPAWYDE. . . . . . . . . . . AGNVYVGRNEDEVRKENNLGADVVLRQDEDVLDTWFSSALWTFSTLGW. . . . . PENTDALRQ
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Template Sequence  IPMVHCVVPVPEEELPVLLPDLKDVEDISPLEAHPEFYETTCPKRDTDTMDTFFDSSWYYLRYTDPHNDRLPFDPEKANA
Template Known Secondary structure 






GGG







S
STT

GGGG






B



TTTTSTT
SSSS

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   434.....440.........450.........460.........470.........480.........490.........500.........510...
 
   499500.........510.........520.........530.........540.........550
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Query Sequence  FHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDD. . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  WMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLGMVKVEEPFQGLFTQGMVLAWTDFGPVEVEGSVVRLPEPTRIRLEIPES
Template Known Secondary structure 
SBS

TT
TTS
S
S
SBS



TT

T
S
S
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   529530.........540.........550.........560.........570.........580.........590.........600........
 
   551........560.........570.........580.........590.........600.....
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . EGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNG
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Template Sequence  ALSLEDVRKMGAELRPHEDGTLHLWKPAVMSKSKGNGVMVGPF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT

TTSS

TTTT


B.....................................
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   609610.........620.........630.........640.........650.
 
   606...610.........620.........630.........640.........650.........660.........670.........680.....
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Query Sequence  IEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTI
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Template Sequence  VKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLETSGVFQA. . EALEGKDRELYGKLHETL
Template Known Secondary structure  S
S
TTS

TT





G..GG

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   652.......660.........670.........680.........690.........700.........710. ........720.........
 
   686...690.........700.........710.........720.........730.........740.........750.........760.....
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Query Sequence  KAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRV
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Template Sequence  KKVTEDLEALRFNTAIAALMEFL. . . . . NALYEYRKDRPV. . . . . . . . . . TPVYRTAIRYYLQMLFPFAPHLAEELWHWF
Template Known Secondary structure  TT
.....S
S..........
TTTSTTT
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   730.........740.........750.. .......760.... .....770.........780.........790....
 
   766...770.........780.........790.
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Query Sequence  KVLCGITADTIMLQPFPQYDASQVDE
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Template Conservation  ......   

    

  
      
Template Sequence  . . . . . . WPDSLFEAGWPELDEKALEK
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SS






TGGG

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   795....800.........810....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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