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Job DescriptionP00363
Confidence99.28%DateThu Jan 5 10:56:34 GMT 2012
Rank169Aligned Residues362
% Identity17%Templatec2v1dA_
PDB info PDB header:oxidoreductase/repressorChain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition
Resolution3.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   7..10.........20.........30.........40......... 50.........60.........70
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Query Sequence  DLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAA. . . . . . . . EGGSAAVAQDHDSFEYHFHDT. . . . . . . .
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Template Sequence  KVIIIGSGVSGLAAARQLQSFG. . MDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIK
Template Known Secondary structure 

STT..

SSSSS
TT

TTSS



SBT
TT



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   280.........290.........300. ........310.........320.........330.........340.........350.......
 
   71........80.........90.......
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Query Sequence  . . . . . VAGGDWLCEQDVVDYFVHHCPTEMTQL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKT
Template Known Secondary structure 




B
TTSSB

TS


TT
B
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   358.360.........370.........380.........390.........400.........410.........420.........430.......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                                                                  
Template Sequence  QEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPS
Template Known Secondary structure  S
SS

TTS


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   438.440.........450.........460.........470.........480.........490.........500.........510.......
 
   98.100.........110.........120.........130.........140.........150.......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . ELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHF
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Template Sequence  DVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGY. . . . . . SCVPVALAE. . GLDIKLNTA
Template Known Secondary structure  S
SS
TTS
TTTBBTTTTTTTGGG

BS

TT
T......TT..T


S
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   518.520.........530.........540.........550.........560.........570. ........580 .........
 
   158.160.........170.........180.........190.........200.........210.........220.........230.......
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Query Sequence  VLDILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGL
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Template Sequence  VRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTL. . . . . . . . . . . . . . . . . . . . . . . . . PLGVLKQQPPAVQFVPPLP
Template Known Secondary structure  TTSSSTT
S

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SS
SSS


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   590.........600.........610.........620..... ....630.........640....
 
   238.240.........250.........260.........270.........280.........290.........300.........310.......
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Query Sequence  PGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDL
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Template Sequence  EWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNL. . . . . . . . . YKAPILLALVAGEAAGIM
Template Known Secondary structure  S



SS

S
TT




SSSTTTTTT

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   645....650.........660.........670.........680.........690....... ..700.........710.....
 
   318.320.........330.........340.........350.. .......360.. .......370....
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Query Sequence  RHLGEKKLHERLPFICELAKAYVGVDPVKEPIPVR. PTAHYTMGGI. . . . . . . . . . . . . . . . . . . . . . ETDQNCETRIKG
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Template Conservation     
  
        
                

 
   
   
  
    
        
  
           
 
  
Template Sequence  ENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPR
Template Known Secondary structure  TTS

TTTS


S

TTT
TTTSSS

BTT

S
B



SSTTS





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   716...720.........730.........740.........750.........760.........770.........780.........790.....
 
   375....380.........390.........400.........410.........
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Query Sequence  LFAVGECSSVGLHGANRLGSNSLAELVVFGRLAGEQATERAATAG
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Template Sequence  LFFAGEHTIRN. . . . . . . YPATVHGALLSGLREAGRIADQFLGAM
Template Known Secondary structure 
SGGG
TT.......STTSS

G
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   796...800...... ...810.........820.........830...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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